Question answering systems for health professionals at the point of care -- a systematic review
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Abstract (arXiv)
Objective: Question answering (QA) systems have the potential to improve the quality of clinical care by providing health professionals with the latest and most relevant evidence. However, QA systems have not been widely adopted. This systematic review aims to characterize current medical QA systems, assess their suitability for healthcare, and identify areas of improvement. Materials and methods: We searched PubMed, IEEE Xplore, ACM Digital Library, ACL Anthology and forward and backward citations on 7th February 2023. We included peer-reviewed journal and conference papers describing the design and evaluation of biomedical QA systems. Two reviewers screened titles, abstracts, and full-text articles. We conducted a narrative synthesis and risk of bias assessment for each study. We assessed the utility of biomedical QA systems. Results: We included 79 studies and identified themes, including question realism, answer reliability, answer utility, clinical specialism, systems, usability, and evaluation methods. Clinicians' questions used to train and evaluate QA systems were restricted to certain sources, types and complexity levels. No system communicated confidence levels in the answers or sources. Many studies suffered from high risks of bias and applicability concerns. Only 8 studies completely satisfied any criterion for clinical utility, and only 7 reported user evaluations. Most systems were built with limited input from clinicians. Discussion: While machine learning methods have led to increased accuracy, most studies imperfectly reflected real-world healthcare information needs. Key research priorities include developing more realistic healthcare QA datasets and considering the reliability of answer sources, rather than merely focusing on accuracy.
Key facts. Cited by 3 papers in the map (data through 7 Oct 2026). Builds on 32 of its 123 references that are in the map. First posted on arXiv 24 Jan 2024.
Builds on
32 of 123 references.
References · 32
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20 more
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Built on by
Citing papers per year: 2024: 2; 2025: 1.
3 papers.
- 2024RealMedQA: A pilot biomedical question answering dataset containing realistic clinical questionscited by 5
- 2024Optimized Biomedical Question-Answering Services with LLM and Multi-BERT Integrationcited by 2
- 2025ECG-LLM -- training and evaluation of domain-specific large language models for electrocardiographycited by 0
- 2025ECG-LLM -- training and evaluation of domain-specific large language models for electrocardiography21 Oct 2025
- 2024Optimized Biomedical Question-Answering Services with LLM and Multi-BERT Integration11 Oct 2024
- 2024RealMedQA: A pilot biomedical question answering dataset containing realistic clinical questions16 Aug 2024