RealMedQA: A pilot biomedical question answering dataset containing realistic clinical questions
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Abstract (arXiv)
Clinical question answering systems have the potential to provide clinicians with relevant and timely answers to their questions. Nonetheless, despite the advances that have been made, adoption of these systems in clinical settings has been slow. One issue is a lack of question-answering datasets which reflect the real-world needs of health professionals. In this work, we present RealMedQA, a dataset of realistic clinical questions generated by humans and an LLM. We describe the process for generating and verifying the QA pairs and assess several QA models on BioASQ and RealMedQA to assess the relative difficulty of matching answers to questions. We show that the LLM is more cost-efficient for generating "ideal" QA pairs. Additionally, we achieve a lower lexical similarity between questions and answers than BioASQ which provides an additional challenge to the top two QA models, as per the results. We release our code and our dataset publicly to encourage further research.
Key facts. Cited by 5 papers in the map (data through 14 Oct 2026). Builds on 18 of its 32 references that are in the map. First posted on arXiv 16 Aug 2024.
Builds on
18 of 32 references.
References · 18
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6 more
- 2020Domain-Specific Language Model Pretraining for Biomedical Natural Language Processingcited by 1,009
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Citing papers per year: 2025: 1; 2026: 4.
5 papers.
- 2025A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontierscited by 37
- 2026MedHopQA: A Disease-Centered Multi-Hop Reasoning Benchmark and Evaluation Framework for LLM-Based Biomedical Question Answeringcited by 2
- 2026Quantifying Hallucinations in Language Language Models on Medical Textbookscited by 0
- 2026EuropeMedQA Study Protocol: A Multilingual, Multimodal Medical Examination Dataset for Language Model Evaluationcited by 0
- 2026Can I Take Another Dose? Evaluating LLM Decision-Making Under Temporal Uncertainty in OTC Dosing QAcited by 0
- 2026Can I Take Another Dose? Evaluating LLM Decision-Making Under Temporal Uncertainty in OTC Dosing QA2 Jun 2026
- 2026MedHopQA: A Disease-Centered Multi-Hop Reasoning Benchmark and Evaluation Framework for LLM-Based Biomedical Question Answering12 May 2026
- 2026EuropeMedQA Study Protocol: A Multilingual, Multimodal Medical Examination Dataset for Language Model Evaluation15 Apr 2026
- 2026Quantifying Hallucinations in Language Language Models on Medical Textbooks12 Feb 2026
- 2025A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontiers28 Aug 2025