Neural Domain Adaptation for Biomedical Question Answering
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Abstract (arXiv)
Factoid question answering (QA) has recently benefited from the development of deep learning (DL) systems. Neural network models outperform traditional approaches in domains where large datasets exist, such as SQuAD (ca. 100,000 questions) for Wikipedia articles. However, these systems have not yet been applied to QA in more specific domains, such as biomedicine, because datasets are generally too small to train a DL system from scratch. For example, the BioASQ dataset for biomedical QA comprises less then 900 factoid (single answer) and list (multiple answers) QA instances. In this work, we adapt a neural QA system trained on a large open-domain dataset (SQuAD, source) to a biomedical dataset (BioASQ, target) by employing various transfer learning techniques. Our network architecture is based on a state-of-the-art QA system, extended with biomedical word embeddings and a novel mechanism to answer list questions. In contrast to existing biomedical QA systems, our system does not rely on domain-specific ontologies, parsers or entity taggers, which are expensive to create. Despite this fact, our systems achieve state-of-the-art results on factoid questions and competitive results on list questions.
Key facts. Cited by 30 papers in the map (data through 7 Oct 2026). First posted on arXiv 12 Jun 2017.
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Citing papers per year: 2021: 13; 2022: 8; 2023: 3; 2024: 4; 2025: 2.
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- 2022MERLOT Reserve: Neural Script Knowledge through Vision and Language and Soundcited by 184
- 2021How Should Pre-Trained Language Models Be Fine-Tuned Towards Adversarial Robustness?cited by 49
- 2021Biomedical Question Answering: A Survey of Approaches and Challengescited by 46
- 2024Scaling Laws for Forgetting When Fine-Tuning Large Language Modelscited by 36
- 2023Preserving Pre-trained Features Helps Calibrate Fine-tuned Language Modelscited by 29
- 2021Refining Language Models with Compositional Explanationscited by 27
- 2021Self-Supervised Test-Time Learning for Reading Comprehensioncited by 22
- 2022Learning to Transfer Prompts for Text Generationcited by 22
- 2022Why is constrained neural language generation particularly challenging?cited by 19
- 2021Sequence tagging for biomedical extractive question answeringcited by 12
- 2022Synthetic Question Value Estimation for Domain Adaptation of Question Answeringcited by 12
- 2021Studying Catastrophic Forgetting in Neural Ranking Modelscited by 9
18 more
- 2023Bioformer: an efficient transformer language model for biomedical text miningcited by 9
- 2022On the Usability of Transformers-based models for a French Question-Answering taskcited by 8
- 2023Backward Compatibility During Data Updates by Weight Interpolationcited by 7
- 2022Synthetic Target Domain Supervision for Open Retrieval QAcited by 6
- 2025Applications of Large Models in Medicinecited by 6
- 2021A Neural Question Answering System for Basic Questions about Subroutinescited by 5
- 2021Task-adaptive Pre-training of Language Models with Word Embedding Regularizationcited by 5
- 2021Rumour Detection via Zero-shot Cross-lingual Transfer Learningcited by 5
- 2022Continual Learning of Long Topic Sequences in Neural Information Retrievalcited by 4
- 2024Fine-tuning Large Language Models with Limited Data: A Survey and Practical Guidecited by 4
- 2024Question answering systems for health professionals at the point of care -- a systematic reviewcited by 3
- 2021Neural Supervised Domain Adaptation by Augmenting Pre-trained Models with Random Unitscited by 2
- 2022Task Transfer and Domain Adaptation for Zero-Shot Question Answeringcited by 1
- 2025Supervised In-Context Fine-Tuning for Generative Sequence Labelingcited by 1
- 2021Transformer-based Language Models for Factoid Question Answering at BioASQ9bcited by 0
- 2021Recent Advances in Automated Question Answering In Biomedical Domaincited by 0
- 2021DPRK-BERT: The Supreme Language Modelcited by 0
- 2024Domain-specific or Uncertainty-aware models: Does it really make a difference for biomedical text classification?cited by 0
- 2025Supervised In-Context Fine-Tuning for Generative Sequence Labeling31 Aug 2025
- 2025Applications of Large Models in Medicine24 Feb 2025
- 2024Fine-tuning Large Language Models with Limited Data: A Survey and Practical Guide14 Nov 2024
- 2024Domain-specific or Uncertainty-aware models: Does it really make a difference for biomedical text classification?17 Jul 2024
- 2024Question answering systems for health professionals at the point of care -- a systematic review24 Jan 2024
- 2024Scaling Laws for Forgetting When Fine-Tuning Large Language Models11 Jan 2024
- 2023Preserving Pre-trained Features Helps Calibrate Fine-tuned Language Models30 May 2023
- 2023Bioformer: an efficient transformer language model for biomedical text mining3 Feb 2023
- 2023Backward Compatibility During Data Updates by Weight Interpolation25 Jan 2023
- 2022On the Usability of Transformers-based models for a French Question-Answering task19 Jul 2022
- 2022Task Transfer and Domain Adaptation for Zero-Shot Question Answering14 Jun 2022
- 2022Why is constrained neural language generation particularly challenging?11 Jun 2022
18 more
- 2022Learning to Transfer Prompts for Text Generation3 May 2022
- 2022Synthetic Target Domain Supervision for Open Retrieval QA20 Apr 2022
- 2022Synthetic Question Value Estimation for Domain Adaptation of Question Answering16 Mar 2022
- 2022Continual Learning of Long Topic Sequences in Neural Information Retrieval10 Jan 2022
- 2022MERLOT Reserve: Neural Script Knowledge through Vision and Language and Sound7 Jan 2022
- 2021How Should Pre-Trained Language Models Be Fine-Tuned Towards Adversarial Robustness?22 Dec 2021
- 2021DPRK-BERT: The Supreme Language Model1 Dec 2021
- 2021Recent Advances in Automated Question Answering In Biomedical Domain10 Nov 2021
- 2021Rumour Detection via Zero-shot Cross-lingual Transfer Learning27 Sep 2021
- 2021Task-adaptive Pre-training of Language Models with Word Embedding Regularization17 Sep 2021
- 2021Transformer-based Language Models for Factoid Question Answering at BioASQ9b15 Sep 2021
- 2021Neural Supervised Domain Adaptation by Augmenting Pre-trained Models with Random Units9 Jun 2021
- 2021Sequence tagging for biomedical extractive question answering15 Apr 2021
- 2021Self-Supervised Test-Time Learning for Reading Comprehension20 Mar 2021
- 2021Refining Language Models with Compositional Explanations18 Mar 2021
- 2021Biomedical Question Answering: A Survey of Approaches and Challenges10 Feb 2021
- 2021Studying Catastrophic Forgetting in Neural Ranking Models18 Jan 2021
- 2021A Neural Question Answering System for Basic Questions about Subroutines11 Jan 2021
- 2022MERLOT Reserve: Neural Script Knowledge through Vision and Language and Soundcited by 184
- 2021How Should Pre-Trained Language Models Be Fine-Tuned Towards Adversarial Robustness?cited by 49
- 2021Biomedical Question Answering: A Survey of Approaches and Challengescited by 46
- 2024Scaling Laws for Forgetting When Fine-Tuning Large Language Modelscited by 36
- 2023Preserving Pre-trained Features Helps Calibrate Fine-tuned Language Modelscited by 29
- 2021Refining Language Models with Compositional Explanationscited by 27
- 2021Self-Supervised Test-Time Learning for Reading Comprehensioncited by 22
- 2022Learning to Transfer Prompts for Text Generationcited by 22
- 2022Why is constrained neural language generation particularly challenging?cited by 19
- 2021Sequence tagging for biomedical extractive question answeringcited by 12
- 2022Synthetic Question Value Estimation for Domain Adaptation of Question Answeringcited by 12
- 2021Studying Catastrophic Forgetting in Neural Ranking Modelscited by 9
12 most cited of 30 All 30 (JSON)
- 2025Supervised In-Context Fine-Tuning for Generative Sequence Labeling31 Aug 2025
- 2025Applications of Large Models in Medicine24 Feb 2025
- 2024Fine-tuning Large Language Models with Limited Data: A Survey and Practical Guide14 Nov 2024
- 2024Domain-specific or Uncertainty-aware models: Does it really make a difference for biomedical text classification?17 Jul 2024
- 2024Question answering systems for health professionals at the point of care -- a systematic review24 Jan 2024
- 2024Scaling Laws for Forgetting When Fine-Tuning Large Language Models11 Jan 2024
- 2023Preserving Pre-trained Features Helps Calibrate Fine-tuned Language Models30 May 2023
- 2023Bioformer: an efficient transformer language model for biomedical text mining3 Feb 2023
- 2023Backward Compatibility During Data Updates by Weight Interpolation25 Jan 2023
- 2022On the Usability of Transformers-based models for a French Question-Answering task19 Jul 2022
- 2022Task Transfer and Domain Adaptation for Zero-Shot Question Answering14 Jun 2022
- 2022Why is constrained neural language generation particularly challenging?11 Jun 2022
12 newest of 30 All 30 (JSON)