mlsanityData to 14 Oct 2026

GraphCare: Enhancing Healthcare Predictions with Personalized Knowledge Graphs

arXiv 2305.12788 ↗First posted 22 May 2023cs.AI cs.LGcited by 58

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Abstract (arXiv)

Clinical predictive models often rely on patients' electronic health records (EHR), but integrating medical knowledge to enhance predictions and decision-making is challenging. This is because personalized predictions require personalized knowledge graphs (KGs), which are difficult to generate from patient EHR data. To address this, we propose textscGraphCare, an open-world framework that uses external KGs to improve EHR-based predictions. Our method extracts knowledge from large language models (LLMs) and external biomedical KGs to build patient-specific KGs, which are then used to train our proposed Bi-attention AugmenTed (BAT) graph neural network (GNN) for healthcare predictions. On two public datasets, MIMIC-III and MIMIC-IV, textscGraphCare surpasses baselines in four vital healthcare prediction tasks: mortality, readmission, length of stay (LOS), and drug recommendation. On MIMIC-III, it boosts AUROC by 17.6% and 6.6% for mortality and readmission, and F1-score by 7.9% and 10.8% for LOS and drug recommendation, respectively. Notably, textscGraphCare demonstrates a substantial edge in scenarios with limited data availability. Our findings highlight the potential of using external KGs in healthcare prediction tasks and demonstrate the promise of textscGraphCare in generating personalized KGs for promoting personalized medicine.

Key facts. Cited by 58 papers in the map (data through 14 Oct 2026). Builds on 50 of its 91 references that are in the map. First posted on arXiv 22 May 2023.

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50 of 91 references.

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Cited by year (2026 to 14 Oct)

Citing papers per year: 2024: 12; 2025: 23; 2026: 23.

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  1. 2024ClinicalBench: Can LLMs Beat Traditional ML Models in Clinical Prediction?cited by 32
  2. 2024ColaCare: Enhancing Electronic Health Record Modeling through Large Language Model-Driven Multi-Agent Collaborationcited by 23
  3. 2024EMERGE: Enhancing Multimodal Electronic Health Records Predictive Modeling with Retrieval-Augmented Generationcited by 17
  4. 2024KG-FIT: Knowledge Graph Fine-Tuning Upon Open-World Knowledgecited by 16
  5. 2025Multimodal Medical Code Tokenizercited by 14
  6. 2024Graphusion: A RAG Framework for Knowledge Graph Construction with a Global Perspectivecited by 12
  7. 2024Predictive Modeling with Temporal Graphical Representation on Electronic Health Recordscited by 9
  8. 2025HypKG: Hypergraph-based Knowledge Graph Contextualization for Precision Healthcarecited by 9
  9. 2024SMART: Towards Pre-trained Missing-Aware Model for Patient Health Status Predictioncited by 8
  10. 2025A Survey on Retrieval And Structuring Augmented Generation with Large Language Modelscited by 8
  11. 2024GenRES: Rethinking Evaluation for Generative Relation Extraction in the Era of Large Language Modelscited by 7
  12. 2026EHR-RAG: Bridging Long-Horizon Structured Electronic Health Records and Large Language Models via Enhanced Retrieval-Augmented Generationcited by 6
38 more
  1. 2025Unveiling Discrete Clues: Superior Healthcare Predictions for Rare Diseasescited by 5
  2. 2025No Black Boxes: Interpretable and Interactable Predictive Healthcare with Knowledge-Enhanced Agentic Causal Discoverycited by 5
  3. 2025Multi-Ontology Integration with Dual-Axis Propagation for Medical Concept Representationcited by 4
  4. 2024Bridging Stepwise Lab-Informed Pretraining and Knowledge-Guided Learning for Diagnostic Reasoningcited by 3
  5. 2025Discovering Hierarchy-Grounded Domains with Adaptive Granularity for Clinical Domain Generalizationcited by 3
  6. 2025Toward Better EHR Reasoning in LLMs: Reinforcement Learning with Expert Attention Guidancecited by 3
  7. 2026CLR-voyance: Reinforcing Open-Ended Reasoning for Inpatient Clinical Decision Support with Outcome-Aware Rubricscited by 3
  8. 2024MedG-KRP: Medical Graph Knowledge Representation Probingcited by 2
  9. 2025Diffmv: A Unified Diffusion Framework for Healthcare Predictions with Random Missing Views and View Lazinesscited by 2
  10. 2025Improving Hospital Risk Prediction with Knowledge-Augmented Multimodal EHR Modelingcited by 2
  11. 2025ProtoEHR: Hierarchical Prototype Learning for EHR-based Healthcare Predictionscited by 2
  12. 2025From Knowledge to Treatment: Large Language Model Assisted Biomedical Concept Representation for Drug Repurposingcited by 2
  13. 2024MPLite: Multi-Aspect Pretraining for Mining Clinical Health Recordscited by 1
  14. 2025Reviewing Clinical Knowledge in Medical Large Language Models: Training and Beyondcited by 1
  15. 2025DiaLLMs: EHR Enhanced Clinical Conversational System for Clinical Test Recommendation and Diagnosis Predictioncited by 1
  16. 2025MedCoAct: Confidence-Aware Multi-Agent Collaboration for Complete Clinical Decisioncited by 1
  17. 2025Grounded by Experience: Generative Healthcare Prediction Augmented with Hierarchical Agentic Retrievalcited by 1
  18. 2025Uncertainty-Aware Dynamic Knowledge Graphs for Reliable Question Answeringcited by 1
  19. 2026User-Adaptive Meta-Learning for Cold-Start Medication Recommendation with Uncertainty Filteringcited by 1
  20. 2026Efficient and Effective Internal Memory Retrieval for LLM-Based Healthcare Predictioncited by 1
  21. 2026Text-Attributed Knowledge Graph Enrichment with Large Language Models for Medical Concept Representationcited by 1
  22. 2026RePrompT: Recurrent Prompt Tuning for Integrating Structured EHR Encoders with Large Language Modelscited by 1
  23. 2024IntelliCare: Improving Healthcare Analysis with Variance-Controlled Patient-Level Knowledge from Large Language Modelscited by 0
  24. 2025CKD-EHR:Clinical Knowledge Distillation for Electronic Health Recordscited by 0
  25. 2025Structure-aware Hypergraph Transformer for Diagnosis Prediction in Electronic Health Recordscited by 0
  26. 2025Towards Fair Graph Prompting: A Dual-Prompt Mechanism for Mitigating Attribute and Structural Biascited by 0
  27. 2025Early Risk Prediction with Temporally and Contextually Grounded Clinical Language Processingcited by 0
  28. 2025Beyond Traditional Diagnostics: Transforming Patient-Side Information into Predictive Insights with Knowledge Graphs and Prototypescited by 0
  29. 2025Self-Ensemble Post Learning for Noisy Domain Generalizationcited by 0
  30. 2026ReToP: Learning to Rewrite Electronic Health Records for Clinical Predictioncited by 0
  31. 2026What Drives Length of Stay After Elective Spine Surgery? Insights from a Decade of Predictive Modelingcited by 0
  32. 2026MIRAGE: Knowledge Graph-Guided Cross-Cohort MRI Synthesis for Alzheimer's Disease Predictioncited by 0
  33. 2026EviCare: Enhancing Diagnosis Prediction with Deep Model-Guided Evidence for In-Context Reasoningcited by 0
  34. 2026LogosKG: Hardware-Optimized Scalable and Interpretable Knowledge Graph Retrievalcited by 0
  35. 2026Learning to Select Source-Traceable Evidence for Language-Model Prediction from Irregular Clinical Time Seriescited by 0
  36. 2026GraD-IBD: Graph Representation Learning from Diagnosis Trajectories for Early Detection of Inflammatory Bowel Diseasecited by 0
  37. 2026HoT-SSM:Higher-order Temporal Knowledge Graph Reasoning with State Space Models for Health Carecited by 0
  38. 2026Personal Care Utility: Health as Everyday Infrastructurecited by 0

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