Backdoor Attack and Defense in Federated Generative Adversarial Network-based Medical Image Synthesis
On the map: LLM safety and security → Federated unlearning and poisoning
Abstract (arXiv)
Deep Learning-based image synthesis techniques have been applied in healthcare research for generating medical images to support open research and augment medical datasets. Training generative adversarial neural networks (GANs) usually require large amounts of training data. Federated learning (FL) provides a way of training a central model using distributed data while keeping raw data locally. However, given that the FL server cannot access the raw data, it is vulnerable to backdoor attacks, an adversarial by poisoning training data. Most backdoor attack strategies focus on classification models and centralized domains. It is still an open question if the existing backdoor attacks can affect GAN training and, if so, how to defend against the attack in the FL setting. In this work, we investigate the overlooked issue of backdoor attacks in federated GANs (FedGANs). The success of this attack is subsequently determined to be the result of some local discriminators overfitting the poisoned data and corrupting the local GAN equilibrium, which then further contaminates other clients when averaging the generator's parameters and yields high generator loss. Therefore, we proposed FedDetect, an efficient and effective way of defending against the backdoor attack in the FL setting, which allows the server to detect the client's adversarial behavior based on their losses and block the malicious clients. Our extensive experiments on two medical datasets with different modalities demonstrate the backdoor attack on FedGANs can result in synthetic images with low fidelity. After detecting and suppressing the detected malicious clients using the proposed defense strategy, we show that FedGANs can synthesize high-quality medical datasets (with labels) for data augmentation to improve classification models' performance.
Key facts. Cited by 12 papers in the map (data through 14 Oct 2026). Placed in Federated unlearning and poisoning, one of 12 directions in LLM safety and security. Builds on 53 of its 85 references that are in the map. First posted on arXiv 19 Oct 2022.
Builds on
53 of 85 references.
References · 53
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38 more
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50 most cited of 53 All 53 (JSON)
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Citing papers per year: 2023: 2; 2024: 8; 2025: 1; 2026: 1.
12 papers.
- 2023Backdoor Attacks and Defenses in Federated Learning: Survey, Challenges and Future Research Directionscited by 33
- 2024BAPLe: Backdoor Attacks on Medical Foundational Models using Prompt Learningcited by 16
- 2024From Challenges and Pitfalls to Recommendations and Opportunities: Implementing Federated Learning in Healthcarecited by 16
- 2024Threats and Defenses in Federated Learning Life Cycle: A Comprehensive Survey and Challengescited by 15
- 2025Can Textual Gradient Work in Federated Learning?cited by 15
- 2024Invisible Backdoor Attack against Self-supervised Learningcited by 6
- 2023Forgettable Federated Linear Learning with Certified Data Unlearningcited by 5
- 2024Backdoor Attack on Unpaired Medical Image-Text Foundation Models: A Pilot Study on MedCLIPcited by 5
- 2024A Systematic Review of Federated Generative Modelscited by 5
- 2024SoK: Security and Privacy Risks of Healthcare AIcited by 2
- 2024FedBlock: A Blockchain Approach to Federated Learning against Backdoor Attackscited by 2
- 2026FL-MedSegBench: A Comprehensive Benchmark for Federated Learning on Medical Image Segmentationcited by 0
- 2026FL-MedSegBench: A Comprehensive Benchmark for Federated Learning on Medical Image Segmentation12 Mar 2026
- 2025Can Textual Gradient Work in Federated Learning?27 Feb 2025
- 2024FedBlock: A Blockchain Approach to Federated Learning against Backdoor Attacks5 Nov 2024
- 2024From Challenges and Pitfalls to Recommendations and Opportunities: Implementing Federated Learning in Healthcare15 Sep 2024
- 2024SoK: Security and Privacy Risks of Healthcare AI11 Sep 2024
- 2024BAPLe: Backdoor Attacks on Medical Foundational Models using Prompt Learning14 Aug 2024
- 2024Threats and Defenses in Federated Learning Life Cycle: A Comprehensive Survey and Challenges9 Jul 2024
- 2024A Systematic Review of Federated Generative Models26 May 2024
- 2024Invisible Backdoor Attack against Self-supervised Learning23 May 2024
- 2024Backdoor Attack on Unpaired Medical Image-Text Foundation Models: A Pilot Study on MedCLIP1 Jan 2024
- 2023Forgettable Federated Linear Learning with Certified Data Unlearning3 Jun 2023
- 2023Backdoor Attacks and Defenses in Federated Learning: Survey, Challenges and Future Research Directions3 Mar 2023
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- 2024GANcrop: A Contrastive Defense Against Backdoor Attacks in Federated Learning
- 2023Mitigating Cross-client GANs-based Attack in Federated Learning
- 2024A Model Consistency-Based Countermeasure to GAN-Based Data Poisoning Attack in Federated Learning
- 2024Adversarially Guided Stateful Defense Against Backdoor Attacks in Federated Deep Learning
- 2024Client-Side Patching against Backdoor Attacks in Federated Learning
- 2023FedGrad: Mitigating Backdoor Attacks in Federated Learning Through Local Ultimate Gradients Inspection
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