mlsanityData to 7 Oct 2026

MONAI Label: A framework for AI-assisted Interactive Labeling of 3D Medical Images

arXiv 2203.12362 ↗First posted 23 Mar 2022cs.HC cs.CV cs.LGcited by 38

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Abstract (arXiv)

The lack of annotated datasets is a major bottleneck for training new task-specific supervised machine learning models, considering that manual annotation is extremely expensive and time-consuming. To address this problem, we present MONAI Label, a free and open-source framework that facilitates the development of applications based on artificial intelligence (AI) models that aim at reducing the time required to annotate radiology datasets. Through MONAI Label, researchers can develop AI annotation applications focusing on their domain of expertise. It allows researchers to readily deploy their apps as services, which can be made available to clinicians via their preferred user interface. Currently, MONAI Label readily supports locally installed (3D Slicer) and web-based (OHIF) frontends and offers two active learning strategies to facilitate and speed up the training of segmentation algorithms. MONAI Label allows researchers to make incremental improvements to their AI-based annotation application by making them available to other researchers and clinicians alike. Additionally, MONAI Label provides sample AI-based interactive and non-interactive labeling applications, that can be used directly off the shelf, as plug-and-play to any given dataset. Significant reduced annotation times using the interactive model can be observed on two public datasets.

Key facts. Cited by 38 papers in the map (data through 7 Oct 2026). Builds on 22 of its 48 references that are in the map. First posted on arXiv 23 Mar 2022.

Builds on

22 of 48 references.

References · 22

  1. 2017Attention Is All You Needcited by 59,932
  2. 2015Deep Residual Learning for Image Recognitioncited by 51,809
  3. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
  4. 2016V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentationcited by 2,284
  5. 20163D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotationcited by 1,471
  6. 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 954
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  8. 2021The Medical Segmentation Decathloncited by 620
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  10. 2019Kornia: an Open Source Differentiable Computer Vision Library for PyTorchcited by 231
  11. 2016Deep Interactive Object Selectioncited by 160
  12. 2017Suggestive Annotation: A Deep Active Learning Framework for Biomedical Image Segmentationcited by 145
10 more
  1. 2017Deep Extreme Cut: From Extreme Points to Object Segmentationcited by 127
  2. 2017DeepIGeoS: A Deep Interactive Geodesic Framework for Medical Image Segmentationcited by 110
  3. 2017Interactive Medical Image Segmentation using Deep Learning with Image-specific Fine-tuningcited by 110
  4. 2021DiNTS: Differentiable Neural Network Topology Search for 3D Medical Image Segmentationcited by 47
  5. 2021MIDeepSeg: Minimally Interactive Segmentation of Unseen Objects from Medical Images Using Deep Learningcited by 45
  6. 2021Diminishing Uncertainty within the Training Pool: Active Learning for Medical Image Segmentationcited by 44
  7. 2020Going to Extremes: Weakly Supervised Medical Image Segmentationcited by 38
  8. 2018Interactive Full Image Segmentation by Considering All Regions Jointlycited by 34
  9. 2019Interactive segmentation of medical images through fully convolutional neural networkscited by 29
  10. 2018Cost-Sensitive Active Learning for Intracranial Hemorrhage Detectioncited by 28

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2022: 1; 2023: 7; 2024: 13; 2025: 6; 2026: 11.

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  1. 2022MONAI: An open-source framework for deep learning in healthcarecited by 438
  2. 2023Deep Interactive Segmentation of Medical Images: A Systematic Review and Taxonomycited by 26
  3. 2025PanTS: The Pancreatic Tumor Segmentation Datasetcited by 15
  4. 2024MultiverSeg: Scalable Interactive Segmentation of Biomedical Imaging Datasets with In-Context Guidancecited by 11
  5. 2023Multimodal Interactive Lung Lesion Segmentation: A Framework for Annotating PET/CT Images based on Physiological and Anatomical Cuescited by 6
  6. 2023Deepbet: Fast brain extraction of T1-weighted MRI using Convolutional Neural Networkscited by 6
  7. 2024MRSegmentator: Multi-Modality Segmentation of 40 Classes in MRI and CTcited by 6
  8. 2023Guiding the Guidance: A Comparative Analysis of User Guidance Signals for Interactive Segmentation of Volumetric Imagescited by 5
  9. 2026MedOpenClaw and MedFlowBench: Auditing Medical Agents in Full-Study Workflowscited by 5
  10. 2024Synthetic Data for Robust Stroke Segmentationcited by 4
  11. 2026RadThinking: A Dataset for Longitudinal Clinical Reasoning in Radiologycited by 4
  12. 2023Adaptive Multi-scale Online Likelihood Network for AI-assisted Interactive Segmentationcited by 3
26 more
  1. 2023Sliding Window FastEdit: A Framework for Lesion Annotation in Whole-body PET Imagescited by 3
  2. 2024Anytime, Anywhere, Anyone: Investigating the Feasibility of Segment Anything Model for Crowd-Sourcing Medical Image Annotationscited by 2
  3. 2024Rethinking Annotator Simulation: Realistic Evaluation of Whole-Body PET Lesion Interactive Segmentation Methodscited by 2
  4. 2024Improve Cross-Modality Segmentation by Treating T1-Weighted MRI Images as Inverted CT Scanscited by 2
  5. 2024Segment Anything Model for automated image data annotation: empirical studies using text prompts from Grounding DINOcited by 2
  6. 2024Conformal Risk Control for Pulmonary Nodule Detectioncited by 2
  7. 2023JoB-VS: Joint Brain-Vessel Segmentation in TOF-MRA Imagescited by 1
  8. 2024Segment Any Medical Model Extendedcited by 1
  9. 2025Towards MR-Based Trochleoplasty Planningcited by 1
  10. 2025Revisiting Data Scaling in Medical Image Segmentation via Topology-Aware Augmentationcited by 1
  11. 2026Finally Outshining the Random Baseline: A Simple and Effective Solution for Active Learning in 3D Biomedical Imagingcited by 1
  12. 2026X-Mark: Saliency-Guided Robust Dataset Ownership Verification for Medical Imagingcited by 1
  13. 2026A Framework for Cross-Domain Generalization in Coronary Artery Calcium Scoring Across Gated and Non-Gated Computed Tomographycited by 1
  14. 2024Minimally Interactive Segmentation of Soft-Tissue Tumors on CT and MRI using Deep Learningcited by 0
  15. 2024Incorporating Anatomical Awareness for Enhanced Generalizability and Progression Prediction in Deep Learning-Based Radiographic Sacroiliitis Detectioncited by 0
  16. 2024deepmriprep: Voxel-based Morphometry (VBM) Preprocessing via Deep Neural Networkscited by 0
  17. 2024SAM Carries the Burden: A Semi-Supervised Approach Refining Pseudo Labels for Medical Segmentationcited by 0
  18. 2025MAIS: Memory-Attention for Interactive Segmentationcited by 0
  19. 2025Benchmarking of Deep Learning Methods for Generic MRI Multi-Organ Abdominal Segmentationcited by 0
  20. 2025MOIS-SAM2: Exemplar-based Segment Anything Model 2 for multilesion interactive segmentation of neurofibromas in whole-body MRIcited by 0
  21. 2026Interactive Medical-SAM2 GUI: A Napari-based semi-automatic annotation tool for medical imagescited by 0
  22. 2026A Clinician-Centered Pipeline for Annotation and Evaluation in Ultrasound AI Studiescited by 0
  23. 2026CyberNeuro: A Privacy-Preserving Agentic Workbench for Cohort-Scale Neuroimage and Clinical Data Analysiscited by 0
  24. 2026OsteoCAD: A Human-in-the-Loop Cloud-Edge Framework for Bone Tumor Segmentationcited by 0
  25. 2026Expert-like Bone Ultrasound Segmentation through Expert-in-the-loop Mask-conditioned Progressive Learningcited by 0
  26. 2026Uncertainty-Guided Handshake: Efficient Human-in-the-Loop Refinement for Surgical-Grade Glioma Segmentationcited by 0