MONAI Label: A framework for AI-assisted Interactive Labeling of 3D Medical Images
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Abstract (arXiv)
The lack of annotated datasets is a major bottleneck for training new task-specific supervised machine learning models, considering that manual annotation is extremely expensive and time-consuming. To address this problem, we present MONAI Label, a free and open-source framework that facilitates the development of applications based on artificial intelligence (AI) models that aim at reducing the time required to annotate radiology datasets. Through MONAI Label, researchers can develop AI annotation applications focusing on their domain of expertise. It allows researchers to readily deploy their apps as services, which can be made available to clinicians via their preferred user interface. Currently, MONAI Label readily supports locally installed (3D Slicer) and web-based (OHIF) frontends and offers two active learning strategies to facilitate and speed up the training of segmentation algorithms. MONAI Label allows researchers to make incremental improvements to their AI-based annotation application by making them available to other researchers and clinicians alike. Additionally, MONAI Label provides sample AI-based interactive and non-interactive labeling applications, that can be used directly off the shelf, as plug-and-play to any given dataset. Significant reduced annotation times using the interactive model can be observed on two public datasets.
Key facts. Cited by 38 papers in the map (data through 7 Oct 2026). Builds on 22 of its 48 references that are in the map. First posted on arXiv 23 Mar 2022.
Builds on
22 of 48 references.
References · 22
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10 more
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Citing papers per year: 2022: 1; 2023: 7; 2024: 13; 2025: 6; 2026: 11.
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- 2022MONAI: An open-source framework for deep learning in healthcarecited by 438
- 2023Deep Interactive Segmentation of Medical Images: A Systematic Review and Taxonomycited by 26
- 2025PanTS: The Pancreatic Tumor Segmentation Datasetcited by 15
- 2024MultiverSeg: Scalable Interactive Segmentation of Biomedical Imaging Datasets with In-Context Guidancecited by 11
- 2023Multimodal Interactive Lung Lesion Segmentation: A Framework for Annotating PET/CT Images based on Physiological and Anatomical Cuescited by 6
- 2023Deepbet: Fast brain extraction of T1-weighted MRI using Convolutional Neural Networkscited by 6
- 2024MRSegmentator: Multi-Modality Segmentation of 40 Classes in MRI and CTcited by 6
- 2023Guiding the Guidance: A Comparative Analysis of User Guidance Signals for Interactive Segmentation of Volumetric Imagescited by 5
- 2026MedOpenClaw and MedFlowBench: Auditing Medical Agents in Full-Study Workflowscited by 5
- 2024Synthetic Data for Robust Stroke Segmentationcited by 4
- 2026RadThinking: A Dataset for Longitudinal Clinical Reasoning in Radiologycited by 4
- 2023Adaptive Multi-scale Online Likelihood Network for AI-assisted Interactive Segmentationcited by 3
26 more
- 2023Sliding Window FastEdit: A Framework for Lesion Annotation in Whole-body PET Imagescited by 3
- 2024Anytime, Anywhere, Anyone: Investigating the Feasibility of Segment Anything Model for Crowd-Sourcing Medical Image Annotationscited by 2
- 2024Rethinking Annotator Simulation: Realistic Evaluation of Whole-Body PET Lesion Interactive Segmentation Methodscited by 2
- 2024Improve Cross-Modality Segmentation by Treating T1-Weighted MRI Images as Inverted CT Scanscited by 2
- 2024Segment Anything Model for automated image data annotation: empirical studies using text prompts from Grounding DINOcited by 2
- 2024Conformal Risk Control for Pulmonary Nodule Detectioncited by 2
- 2023JoB-VS: Joint Brain-Vessel Segmentation in TOF-MRA Imagescited by 1
- 2024Segment Any Medical Model Extendedcited by 1
- 2025Towards MR-Based Trochleoplasty Planningcited by 1
- 2025Revisiting Data Scaling in Medical Image Segmentation via Topology-Aware Augmentationcited by 1
- 2026Finally Outshining the Random Baseline: A Simple and Effective Solution for Active Learning in 3D Biomedical Imagingcited by 1
- 2026X-Mark: Saliency-Guided Robust Dataset Ownership Verification for Medical Imagingcited by 1
- 2026A Framework for Cross-Domain Generalization in Coronary Artery Calcium Scoring Across Gated and Non-Gated Computed Tomographycited by 1
- 2024Minimally Interactive Segmentation of Soft-Tissue Tumors on CT and MRI using Deep Learningcited by 0
- 2024Incorporating Anatomical Awareness for Enhanced Generalizability and Progression Prediction in Deep Learning-Based Radiographic Sacroiliitis Detectioncited by 0
- 2024deepmriprep: Voxel-based Morphometry (VBM) Preprocessing via Deep Neural Networkscited by 0
- 2024SAM Carries the Burden: A Semi-Supervised Approach Refining Pseudo Labels for Medical Segmentationcited by 0
- 2025MAIS: Memory-Attention for Interactive Segmentationcited by 0
- 2025Benchmarking of Deep Learning Methods for Generic MRI Multi-Organ Abdominal Segmentationcited by 0
- 2025MOIS-SAM2: Exemplar-based Segment Anything Model 2 for multilesion interactive segmentation of neurofibromas in whole-body MRIcited by 0
- 2026Interactive Medical-SAM2 GUI: A Napari-based semi-automatic annotation tool for medical imagescited by 0
- 2026A Clinician-Centered Pipeline for Annotation and Evaluation in Ultrasound AI Studiescited by 0
- 2026CyberNeuro: A Privacy-Preserving Agentic Workbench for Cohort-Scale Neuroimage and Clinical Data Analysiscited by 0
- 2026OsteoCAD: A Human-in-the-Loop Cloud-Edge Framework for Bone Tumor Segmentationcited by 0
- 2026Expert-like Bone Ultrasound Segmentation through Expert-in-the-loop Mask-conditioned Progressive Learningcited by 0
- 2026Uncertainty-Guided Handshake: Efficient Human-in-the-Loop Refinement for Surgical-Grade Glioma Segmentationcited by 0
- 2026Uncertainty-Guided Handshake: Efficient Human-in-the-Loop Refinement for Surgical-Grade Glioma Segmentation1 Oct 2026
- 2026Expert-like Bone Ultrasound Segmentation through Expert-in-the-loop Mask-conditioned Progressive Learning31 Aug 2026
- 2026OsteoCAD: A Human-in-the-Loop Cloud-Edge Framework for Bone Tumor Segmentation31 Jul 2026
- 2026CyberNeuro: A Privacy-Preserving Agentic Workbench for Cohort-Scale Neuroimage and Clinical Data Analysis30 Jul 2026
- 2026A Clinician-Centered Pipeline for Annotation and Evaluation in Ultrasound AI Studies17 Jun 2026
- 2026RadThinking: A Dataset for Longitudinal Clinical Reasoning in Radiology11 May 2026
- 2026MedOpenClaw and MedFlowBench: Auditing Medical Agents in Full-Study Workflows25 Mar 2026
- 2026Interactive Medical-SAM2 GUI: A Napari-based semi-automatic annotation tool for medical images26 Feb 2026
- 2026A Framework for Cross-Domain Generalization in Coronary Artery Calcium Scoring Across Gated and Non-Gated Computed Tomography25 Feb 2026
- 2026X-Mark: Saliency-Guided Robust Dataset Ownership Verification for Medical Imaging10 Feb 2026
- 2026Finally Outshining the Random Baseline: A Simple and Effective Solution for Active Learning in 3D Biomedical Imaging20 Jan 2026
- 2025Revisiting Data Scaling in Medical Image Segmentation via Topology-Aware Augmentation17 Nov 2025
26 more
- 2025MOIS-SAM2: Exemplar-based Segment Anything Model 2 for multilesion interactive segmentation of neurofibromas in whole-body MRI23 Sep 2025
- 2025Towards MR-Based Trochleoplasty Planning8 Aug 2025
- 2025Benchmarking of Deep Learning Methods for Generic MRI Multi-Organ Abdominal Segmentation23 Jul 2025
- 2025PanTS: The Pancreatic Tumor Segmentation Dataset2 Jul 2025
- 2025MAIS: Memory-Attention for Interactive Segmentation12 May 2025
- 2024Conformal Risk Control for Pulmonary Nodule Detection28 Dec 2024
- 2024MultiverSeg: Scalable Interactive Segmentation of Biomedical Imaging Datasets with In-Context Guidance19 Dec 2024
- 2024SAM Carries the Burden: A Semi-Supervised Approach Refining Pseudo Labels for Medical Segmentation19 Nov 2024
- 2024deepmriprep: Voxel-based Morphometry (VBM) Preprocessing via Deep Neural Networks20 Aug 2024
- 2024Segment Anything Model for automated image data annotation: empirical studies using text prompts from Grounding DINO27 Jun 2024
- 2024Incorporating Anatomical Awareness for Enhanced Generalizability and Progression Prediction in Deep Learning-Based Radiographic Sacroiliitis Detection12 May 2024
- 2024MRSegmentator: Multi-Modality Segmentation of 40 Classes in MRI and CT10 May 2024
- 2024Improve Cross-Modality Segmentation by Treating T1-Weighted MRI Images as Inverted CT Scans4 May 2024
- 2024Synthetic Data for Robust Stroke Segmentation2 Apr 2024
- 2024Rethinking Annotator Simulation: Realistic Evaluation of Whole-Body PET Lesion Interactive Segmentation Methods2 Apr 2024
- 2024Segment Any Medical Model Extended26 Mar 2024
- 2024Anytime, Anywhere, Anyone: Investigating the Feasibility of Segment Anything Model for Crowd-Sourcing Medical Image Annotations22 Mar 2024
- 2024Minimally Interactive Segmentation of Soft-Tissue Tumors on CT and MRI using Deep Learning12 Feb 2024
- 2023Sliding Window FastEdit: A Framework for Lesion Annotation in Whole-body PET Images24 Nov 2023
- 2023Deep Interactive Segmentation of Medical Images: A Systematic Review and Taxonomy23 Nov 2023
- 2023Deepbet: Fast brain extraction of T1-weighted MRI using Convolutional Neural Networks14 Aug 2023
- 2023JoB-VS: Joint Brain-Vessel Segmentation in TOF-MRA Images16 Apr 2023
- 2023Adaptive Multi-scale Online Likelihood Network for AI-assisted Interactive Segmentation23 Mar 2023
- 2023Guiding the Guidance: A Comparative Analysis of User Guidance Signals for Interactive Segmentation of Volumetric Images13 Mar 2023
- 2023Multimodal Interactive Lung Lesion Segmentation: A Framework for Annotating PET/CT Images based on Physiological and Anatomical Cues24 Jan 2023
- 2022MONAI: An open-source framework for deep learning in healthcare4 Nov 2022
- 2022MONAI: An open-source framework for deep learning in healthcarecited by 438
- 2023Deep Interactive Segmentation of Medical Images: A Systematic Review and Taxonomycited by 26
- 2025PanTS: The Pancreatic Tumor Segmentation Datasetcited by 15
- 2024MultiverSeg: Scalable Interactive Segmentation of Biomedical Imaging Datasets with In-Context Guidancecited by 11
- 2023Multimodal Interactive Lung Lesion Segmentation: A Framework for Annotating PET/CT Images based on Physiological and Anatomical Cuescited by 6
- 2023Deepbet: Fast brain extraction of T1-weighted MRI using Convolutional Neural Networkscited by 6
- 2024MRSegmentator: Multi-Modality Segmentation of 40 Classes in MRI and CTcited by 6
- 2023Guiding the Guidance: A Comparative Analysis of User Guidance Signals for Interactive Segmentation of Volumetric Imagescited by 5
- 2026MedOpenClaw and MedFlowBench: Auditing Medical Agents in Full-Study Workflowscited by 5
- 2024Synthetic Data for Robust Stroke Segmentationcited by 4
- 2026RadThinking: A Dataset for Longitudinal Clinical Reasoning in Radiologycited by 4
- 2023Adaptive Multi-scale Online Likelihood Network for AI-assisted Interactive Segmentationcited by 3
12 most cited of 36 All 36 (JSON)
- 2026Uncertainty-Guided Handshake: Efficient Human-in-the-Loop Refinement for Surgical-Grade Glioma Segmentation1 Oct 2026
- 2026Expert-like Bone Ultrasound Segmentation through Expert-in-the-loop Mask-conditioned Progressive Learning31 Aug 2026
- 2026OsteoCAD: A Human-in-the-Loop Cloud-Edge Framework for Bone Tumor Segmentation31 Jul 2026
- 2026A Clinician-Centered Pipeline for Annotation and Evaluation in Ultrasound AI Studies17 Jun 2026
- 2026RadThinking: A Dataset for Longitudinal Clinical Reasoning in Radiology11 May 2026
- 2026MedOpenClaw and MedFlowBench: Auditing Medical Agents in Full-Study Workflows25 Mar 2026
- 2026Interactive Medical-SAM2 GUI: A Napari-based semi-automatic annotation tool for medical images26 Feb 2026
- 2026A Framework for Cross-Domain Generalization in Coronary Artery Calcium Scoring Across Gated and Non-Gated Computed Tomography25 Feb 2026
- 2026Finally Outshining the Random Baseline: A Simple and Effective Solution for Active Learning in 3D Biomedical Imaging20 Jan 2026
- 2025Revisiting Data Scaling in Medical Image Segmentation via Topology-Aware Augmentation17 Nov 2025
- 2025MOIS-SAM2: Exemplar-based Segment Anything Model 2 for multilesion interactive segmentation of neurofibromas in whole-body MRI23 Sep 2025
- 2025Towards MR-Based Trochleoplasty Planning8 Aug 2025
12 newest of 36 All 36 (JSON)