mlsanityData to 7 Oct 2026

Scribble-Supervised Medical Image Segmentation via Dual-Branch Network and Dynamically Mixed Pseudo Labels Supervision

arXiv 2203.02106 ↗First posted 4 Mar 2022eess.IV cs.CVcited by 64

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Abstract (arXiv)

Medical image segmentation plays an irreplaceable role in computer-assisted diagnosis, treatment planning, and following-up. Collecting and annotating a large-scale dataset is crucial to training a powerful segmentation model, but producing high-quality segmentation masks is an expensive and time-consuming procedure. Recently, weakly-supervised learning that uses sparse annotations (points, scribbles, bounding boxes) for network training has achieved encouraging performance and shown the potential for annotation cost reduction. However, due to the limited supervision signal of sparse annotations, it is still challenging to employ them for networks training directly. In this work, we propose a simple yet efficient scribble-supervised image segmentation method and apply it to cardiac MRI segmentation. Specifically, we employ a dual-branch network with one encoder and two slightly different decoders for image segmentation and dynamically mix the two decoders' predictions to generate pseudo labels for auxiliary supervision. By combining the scribble supervision and auxiliary pseudo labels supervision, the dual-branch network can efficiently learn from scribble annotations end-to-end. Experiments on the public ACDC dataset show that our method performs better than current scribble-supervised segmentation methods and also outperforms several semi-supervised segmentation methods.

Key facts. Cited by 64 papers in the map (data through 7 Oct 2026). Builds on 21 of its 39 references that are in the map. First posted on arXiv 4 Mar 2022.

Builds on

21 of 39 references.

References · 21

  1. 2019PyTorch: An Imperative Style, High-Performance Deep Learning Librarycited by 20,160
  2. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
  3. 2017mixup: Beyond Empirical Risk Minimizationcited by 5,155
  4. 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
  5. 2018ADVENT: Adversarial Entropy Minimization for Domain Adaptation in Semantic Segmentationcited by 623
  6. 2017Mean teachers are better role models: Weight-averaged consistency targets improve semi-supervised deep learning resultscited by 470
  7. 2021Semi-Supervised Semantic Segmentation with Cross Pseudo Supervisioncited by 462
  8. 2019Uncertainty-aware Self-ensembling Model for Semi-supervised 3D Left Atrium Segmentationcited by 378
  9. 2020Semi-Supervised Semantic Segmentation with Cross-Consistency Trainingcited by 375
  10. 2016ScribbleSup: Scribble-Supervised Convolutional Networks for Semantic Segmentationcited by 330
  11. 2020Semi-supervised Medical Image Segmentation through Dual-task Consistencycited by 215
  12. 2018On Regularized Losses for Weakly-supervised CNN Segmentationcited by 121
9 more
  1. 2021Semi-supervised Left Atrium Segmentation with Mutual Consistency Trainingcited by 104
  2. 2020Efficient Semi-Supervised Gross Target Volume of Nasopharyngeal Carcinoma Segmentation via Uncertainty Rectified Pyramid Consistencycited by 102
  3. 2020Scribble2Label: Scribble-Supervised Cell Segmentation via Self-Generating Pseudo-Labels with Consistencycited by 52
  4. 2018Learning to Segment Medical Images with Scribble-Supervision Alonecited by 48
  5. 2021MIDeepSeg: Minimally Interactive Segmentation of Unseen Objects from Medical Images Using Deep Learningcited by 45
  6. 2021Self-Tuning for Data-Efficient Deep Learningcited by 39
  7. 2019Mumford-Shah Loss Functional for Image Segmentation with Deep Learningcited by 35
  8. 2021Inter Extreme Points Geodesics for End-to-End Weakly Supervised Image Segmentationcited by 21
  9. 2020Teach me to segment with mixed supervision: Confident students become masterscited by 8

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2022: 5; 2023: 16; 2024: 26; 2025: 9; 2026: 8.

64 papers.

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  1. 2024Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentationcited by 29
  2. 2024ScribFormer: Transformer Makes CNN Work Better for Scribble-based Medical Image Segmentationcited by 24
  3. 2023ScribbleVC: Scribble-supervised Medical Image Segmentation with Vision-Class Embeddingcited by 23
  4. 2023Towards Segment Anything Model (SAM) for Medical Image Segmentation: A Surveycited by 21
  5. 2024Semi-Mamba-UNet: Pixel-Level Contrastive and Pixel-Level Cross-Supervised Visual Mamba-based UNet for Semi-Supervised Medical Image Segmentationcited by 20
  6. 2024Rethinking Abdominal Organ Segmentation (RAOS) in the clinical scenario: A robustness evaluation benchmark with challenging casescited by 18
  7. 2022PA-Seg: Learning from Point Annotations for 3D Medical Image Segmentation using Contextual Regularization and Cross Knowledge Distillationcited by 16
  8. 2022Scribble2D5: Weakly-Supervised Volumetric Image Segmentation via Scribble Annotationscited by 15
  9. 2023S2ME: Spatial-Spectral Mutual Teaching and Ensemble Learning for Scribble-supervised Polyp Segmentationcited by 15
  10. 2022PyMIC: A deep learning toolkit for annotation-efficient medical image segmentationcited by 14
  11. 2023Weakly supervised segmentation with point annotations for histopathology images via contrast-based variational modelcited by 13
  12. 2023Versatile Medical Image Segmentation Learned from Multi-Source Datasets via Model Self-Disambiguationcited by 12
38 more
  1. 2024MultiverSeg: Scalable Interactive Segmentation of Biomedical Imaging Datasets with In-Context Guidancecited by 11
  2. 2023DIAS: A Dataset and Benchmark for Intracranial Artery Segmentation in DSA sequencescited by 10
  3. 2024FPL+: Filtered Pseudo Label-based Unsupervised Cross-Modality Adaptation for 3D Medical Image Segmentationcited by 10
  4. 2022Non-Iterative Scribble-Supervised Learning with Pacing Pseudo-Masks for Medical Image Segmentationcited by 9
  5. 2023ZScribbleSeg: Zen and the Art of Scribble Supervised Medical Image Segmentationcited by 8
  6. 2023Scribble-Supervised RGB-T Salient Object Detectioncited by 8
  7. 2023Scribble-based 3D Multiple Abdominal Organ Segmentation via Triple-branch Multi-dilated Network with Pixel- and Class-wise Consistencycited by 7
  8. 2024SAM-Driven Weakly Supervised Nodule Segmentation with Uncertainty-Aware Cross Teachingcited by 7
  9. 2024Integrating Deep Metric Learning with Coreset for Active Learning in 3D Segmentationcited by 7
  10. 2023Data efficient deep learning for medical image analysis: A surveycited by 6
  11. 2024FedLPPA: Learning Personalized Prompt and Aggregation for Federated Weakly-supervised Medical Image Segmentationcited by 6
  12. 2022Annotation by Clicks: A Point-Supervised Contrastive Variance Method for Medical Semantic Segmentationcited by 4
  13. 2024Beyond Pixel-Wise Supervision for Medical Image Segmentation: From Traditional Models to Foundation Modelscited by 4
  14. 2024ProCNS: Progressive Prototype Calibration and Noise Suppression for Weakly-Supervised Medical Image Segmentationcited by 3
  15. 2024PCLMix: Weakly Supervised Medical Image Segmentation via Pixel-Level Contrastive Learning and Dynamic Mix Augmentationcited by 3
  16. 2024ModelMix: A New Model-Mixup Strategy to Minimize Vicinal Risk across Tasks for Few-scribble based Cardiac Segmentationcited by 3
  17. 2024From Few to More: Scribble-based Medical Image Segmentation via Masked Context Modeling and Continuous Pseudo Labelscited by 3
  18. 2023Partial Vessels Annotation-based Coronary Artery Segmentation with Self-training and Prototype Learningcited by 2
  19. 2023Boosting Weakly-Supervised Image Segmentation via Representation, Transform, and Compensatorcited by 2
  20. 2024ScribbleVS: Scribble-Supervised Medical Image Segmentation via Dynamic Competitive Pseudo Label Selectioncited by 2
  21. 2025SparseMamba-PCL: Scribble-Supervised Medical Image Segmentation via SAM-Guided Progressive Collaborative Learningcited by 2
  22. 2025Enjoying Information Dividend: Gaze Track-based Medical Weakly Supervised Segmentationcited by 2
  23. 2023Volumetric Medical Image Segmentation via Scribble Annotations and Shape Priorscited by 1
  24. 2024Revisiting 3D Medical Scribble Supervision: Benchmarking Beyond Cardiac Segmentationcited by 1
  25. 2024Weakly-Supervised Learning via Multi-Lateral Decoder Branching for Tool Segmentation in Robot-Assisted Cardiovascular Catheterizationcited by 1
  26. 2024DuEDL: Dual-Branch Evidential Deep Learning for Scribble-Supervised Medical Image Segmentationcited by 1
  27. 2024Weakly Supervised Lymph Nodes Segmentation Based on Partial Instance Annotations with Pre-trained Dual-branch Network and Pseudo Label Learningcited by 1
  28. 2024Labeled-to-Unlabeled Distribution Alignment for Partially-Supervised Multi-Organ Medical Image Segmentationcited by 1
  29. 2024MambaEviScrib: Mamba and Evidence-Guided Consistency Enhance CNN Robustness for Scribble-Based Weakly Supervised Ultrasound Image Segmentationcited by 1
  30. 2025QMaxViT-Unet+: A Query-Based MaxViT-Unet with Edge Enhancement for Scribble-Supervised Segmentation of Medical Imagescited by 1
  31. 2025MedCL: Learning Consistent Anatomy Distribution for Scribble-supervised Medical Image Segmentationcited by 1
  32. 2025Bronchovascular Tree-Guided Weakly Supervised Learning Method for Pulmonary Segment Segmentationcited by 1
  33. 2023ScribblePolyp: Scribble-Supervised Polyp Segmentation through Dual Consistency Alignmentcited by 0
  34. 2023Clean Label Disentangling for Medical Image Segmentation with Noisy Labelscited by 0
  35. 2023AttenScribble: Attentive Similarity Learning for Scribble-Supervised Medical Image Segmentationcited by 0
  36. 2024Skeleton Supervised Airway Segmentationcited by 0
  37. 2024Size Aware Cross-shape Scribble Supervision for Medical Image Segmentationcited by 0
  38. 2024A Bayesian Approach to Weakly-supervised Laparoscopic Image Segmentationcited by 0

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