Scribble-Supervised Medical Image Segmentation via Dual-Branch Network and Dynamically Mixed Pseudo Labels Supervision
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Abstract (arXiv)
Medical image segmentation plays an irreplaceable role in computer-assisted diagnosis, treatment planning, and following-up. Collecting and annotating a large-scale dataset is crucial to training a powerful segmentation model, but producing high-quality segmentation masks is an expensive and time-consuming procedure. Recently, weakly-supervised learning that uses sparse annotations (points, scribbles, bounding boxes) for network training has achieved encouraging performance and shown the potential for annotation cost reduction. However, due to the limited supervision signal of sparse annotations, it is still challenging to employ them for networks training directly. In this work, we propose a simple yet efficient scribble-supervised image segmentation method and apply it to cardiac MRI segmentation. Specifically, we employ a dual-branch network with one encoder and two slightly different decoders for image segmentation and dynamically mix the two decoders' predictions to generate pseudo labels for auxiliary supervision. By combining the scribble supervision and auxiliary pseudo labels supervision, the dual-branch network can efficiently learn from scribble annotations end-to-end. Experiments on the public ACDC dataset show that our method performs better than current scribble-supervised segmentation methods and also outperforms several semi-supervised segmentation methods.
Key facts. Cited by 64 papers in the map (data through 7 Oct 2026). Builds on 21 of its 39 references that are in the map. First posted on arXiv 4 Mar 2022.
Builds on
21 of 39 references.
References · 21
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- 2020Semi-Supervised Semantic Segmentation with Cross-Consistency Trainingcited by 375
- 2016ScribbleSup: Scribble-Supervised Convolutional Networks for Semantic Segmentationcited by 330
- 2020Semi-supervised Medical Image Segmentation through Dual-task Consistencycited by 215
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9 more
- 2021Semi-supervised Left Atrium Segmentation with Mutual Consistency Trainingcited by 104
- 2020Efficient Semi-Supervised Gross Target Volume of Nasopharyngeal Carcinoma Segmentation via Uncertainty Rectified Pyramid Consistencycited by 102
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- 2021MIDeepSeg: Minimally Interactive Segmentation of Unseen Objects from Medical Images Using Deep Learningcited by 45
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Citing papers per year: 2022: 5; 2023: 16; 2024: 26; 2025: 9; 2026: 8.
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- 2024Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentationcited by 29
- 2024ScribFormer: Transformer Makes CNN Work Better for Scribble-based Medical Image Segmentationcited by 24
- 2023ScribbleVC: Scribble-supervised Medical Image Segmentation with Vision-Class Embeddingcited by 23
- 2023Towards Segment Anything Model (SAM) for Medical Image Segmentation: A Surveycited by 21
- 2024Semi-Mamba-UNet: Pixel-Level Contrastive and Pixel-Level Cross-Supervised Visual Mamba-based UNet for Semi-Supervised Medical Image Segmentationcited by 20
- 2024Rethinking Abdominal Organ Segmentation (RAOS) in the clinical scenario: A robustness evaluation benchmark with challenging casescited by 18
- 2022PA-Seg: Learning from Point Annotations for 3D Medical Image Segmentation using Contextual Regularization and Cross Knowledge Distillationcited by 16
- 2022Scribble2D5: Weakly-Supervised Volumetric Image Segmentation via Scribble Annotationscited by 15
- 2023S2ME: Spatial-Spectral Mutual Teaching and Ensemble Learning for Scribble-supervised Polyp Segmentationcited by 15
- 2022PyMIC: A deep learning toolkit for annotation-efficient medical image segmentationcited by 14
- 2023Weakly supervised segmentation with point annotations for histopathology images via contrast-based variational modelcited by 13
- 2023Versatile Medical Image Segmentation Learned from Multi-Source Datasets via Model Self-Disambiguationcited by 12
38 more
- 2024MultiverSeg: Scalable Interactive Segmentation of Biomedical Imaging Datasets with In-Context Guidancecited by 11
- 2023DIAS: A Dataset and Benchmark for Intracranial Artery Segmentation in DSA sequencescited by 10
- 2024FPL+: Filtered Pseudo Label-based Unsupervised Cross-Modality Adaptation for 3D Medical Image Segmentationcited by 10
- 2022Non-Iterative Scribble-Supervised Learning with Pacing Pseudo-Masks for Medical Image Segmentationcited by 9
- 2023ZScribbleSeg: Zen and the Art of Scribble Supervised Medical Image Segmentationcited by 8
- 2023Scribble-Supervised RGB-T Salient Object Detectioncited by 8
- 2023Scribble-based 3D Multiple Abdominal Organ Segmentation via Triple-branch Multi-dilated Network with Pixel- and Class-wise Consistencycited by 7
- 2024SAM-Driven Weakly Supervised Nodule Segmentation with Uncertainty-Aware Cross Teachingcited by 7
- 2024Integrating Deep Metric Learning with Coreset for Active Learning in 3D Segmentationcited by 7
- 2023Data efficient deep learning for medical image analysis: A surveycited by 6
- 2024FedLPPA: Learning Personalized Prompt and Aggregation for Federated Weakly-supervised Medical Image Segmentationcited by 6
- 2022Annotation by Clicks: A Point-Supervised Contrastive Variance Method for Medical Semantic Segmentationcited by 4
- 2024Beyond Pixel-Wise Supervision for Medical Image Segmentation: From Traditional Models to Foundation Modelscited by 4
- 2024ProCNS: Progressive Prototype Calibration and Noise Suppression for Weakly-Supervised Medical Image Segmentationcited by 3
- 2024PCLMix: Weakly Supervised Medical Image Segmentation via Pixel-Level Contrastive Learning and Dynamic Mix Augmentationcited by 3
- 2024ModelMix: A New Model-Mixup Strategy to Minimize Vicinal Risk across Tasks for Few-scribble based Cardiac Segmentationcited by 3
- 2024From Few to More: Scribble-based Medical Image Segmentation via Masked Context Modeling and Continuous Pseudo Labelscited by 3
- 2023Partial Vessels Annotation-based Coronary Artery Segmentation with Self-training and Prototype Learningcited by 2
- 2023Boosting Weakly-Supervised Image Segmentation via Representation, Transform, and Compensatorcited by 2
- 2024ScribbleVS: Scribble-Supervised Medical Image Segmentation via Dynamic Competitive Pseudo Label Selectioncited by 2
- 2025SparseMamba-PCL: Scribble-Supervised Medical Image Segmentation via SAM-Guided Progressive Collaborative Learningcited by 2
- 2025Enjoying Information Dividend: Gaze Track-based Medical Weakly Supervised Segmentationcited by 2
- 2023Volumetric Medical Image Segmentation via Scribble Annotations and Shape Priorscited by 1
- 2024Revisiting 3D Medical Scribble Supervision: Benchmarking Beyond Cardiac Segmentationcited by 1
- 2024Weakly-Supervised Learning via Multi-Lateral Decoder Branching for Tool Segmentation in Robot-Assisted Cardiovascular Catheterizationcited by 1
- 2024DuEDL: Dual-Branch Evidential Deep Learning for Scribble-Supervised Medical Image Segmentationcited by 1
- 2024Weakly Supervised Lymph Nodes Segmentation Based on Partial Instance Annotations with Pre-trained Dual-branch Network and Pseudo Label Learningcited by 1
- 2024Labeled-to-Unlabeled Distribution Alignment for Partially-Supervised Multi-Organ Medical Image Segmentationcited by 1
- 2024MambaEviScrib: Mamba and Evidence-Guided Consistency Enhance CNN Robustness for Scribble-Based Weakly Supervised Ultrasound Image Segmentationcited by 1
- 2025QMaxViT-Unet+: A Query-Based MaxViT-Unet with Edge Enhancement for Scribble-Supervised Segmentation of Medical Imagescited by 1
- 2025MedCL: Learning Consistent Anatomy Distribution for Scribble-supervised Medical Image Segmentationcited by 1
- 2025Bronchovascular Tree-Guided Weakly Supervised Learning Method for Pulmonary Segment Segmentationcited by 1
- 2023ScribblePolyp: Scribble-Supervised Polyp Segmentation through Dual Consistency Alignmentcited by 0
- 2023Clean Label Disentangling for Medical Image Segmentation with Noisy Labelscited by 0
- 2023AttenScribble: Attentive Similarity Learning for Scribble-Supervised Medical Image Segmentationcited by 0
- 2024Skeleton Supervised Airway Segmentationcited by 0
- 2024Size Aware Cross-shape Scribble Supervision for Medical Image Segmentationcited by 0
- 2024A Bayesian Approach to Weakly-supervised Laparoscopic Image Segmentationcited by 0
50 most cited of 64 All 64 (JSON)
- 2026GazeRefine: Expert Gaze as a Test-Time Prompt for Training-Free Medical Image Segmentation1 Sep 2026
- 2026Prompt-Conditioned Channel Attention for Hierarchical Feature Modulation toward Anatomy-Agnostic Segmentation20 Aug 2026
- 2026Bi-Level Collaborative Learning for Few-Shot Scribble-Supervised Medical Image Segmentation28 Jul 2026
- 2026Mutual Distillation of Dual-Foundation Models for Semi-Supervised PET/CT Segmentation14 Jun 2026
- 2026DiffSegLung: Diffusion Radiomic Distillation for Unsupervised Lung Pathology Segmentation12 May 2026
- 2026ZScribbleSeg: A comprehensive segmentation framework with modeling of efficient annotation and maximization of scribble supervision7 May 2026
- 2026PLESS: Pseudo-Label Enhancement with Spreading Scribbles for Weakly Supervised Segmentation12 Feb 2026
- 2026Scribble-Supervised Medical Image Segmentation with Dynamic Teacher Switching and Hierarchical Consistency21 Jan 2026
- 2025Needles in the Landscape: Semi-Supervised Pseudolabeling for Archaeological Site Discovery under Label Scarcity19 Oct 2025
- 2025SynMatch: Rethinking Consistency in Medical Image Segmentation with Sparse Annotations10 Aug 2025
- 2025TABNet: A Triplet Augmentation Self-Recovery Framework with Boundary-Aware Pseudo-Labels for Medical Image Segmentation3 Jul 2025
- 2025CmFNet: Cross-modal Fusion Network for Weakly-supervised Segmentation of Medical Images22 Jun 2025
38 more
- 2025Enjoying Information Dividend: Gaze Track-based Medical Weakly Supervised Segmentation28 May 2025
- 2025Bronchovascular Tree-Guided Weakly Supervised Learning Method for Pulmonary Segment Segmentation20 May 2025
- 2025MedCL: Learning Consistent Anatomy Distribution for Scribble-supervised Medical Image Segmentation28 Mar 2025
- 2025SparseMamba-PCL: Scribble-Supervised Medical Image Segmentation via SAM-Guided Progressive Collaborative Learning3 Mar 2025
- 2025QMaxViT-Unet+: A Query-Based MaxViT-Unet with Edge Enhancement for Scribble-Supervised Segmentation of Medical Images14 Feb 2025
- 2024MultiverSeg: Scalable Interactive Segmentation of Biomedical Imaging Datasets with In-Context Guidance19 Dec 2024
- 2024Integrating Deep Metric Learning with Coreset for Active Learning in 3D Segmentation24 Nov 2024
- 2024Text-Driven Weakly Supervised OCT Lesion Segmentation with Structural Guidance19 Nov 2024
- 2024SP 3 : Superpixel-propagated pseudo-label learning for weakly semi-supervised medical image segmentation18 Nov 2024
- 2024ScribbleVS: Scribble-Supervised Medical Image Segmentation via Dynamic Competitive Pseudo Label Selection15 Nov 2024
- 2024A Bayesian Approach to Weakly-supervised Laparoscopic Image Segmentation11 Oct 2024
- 2024MambaEviScrib: Mamba and Evidence-Guided Consistency Enhance CNN Robustness for Scribble-Based Weakly Supervised Ultrasound Image Segmentation28 Sep 2024
- 2024Labeled-to-Unlabeled Distribution Alignment for Partially-Supervised Multi-Organ Medical Image Segmentation5 Sep 2024
- 2024Size Aware Cross-shape Scribble Supervision for Medical Image Segmentation24 Aug 2024
- 2024From Few to More: Scribble-based Medical Image Segmentation via Masked Context Modeling and Continuous Pseudo Labels23 Aug 2024
- 2024Weakly Supervised Lymph Nodes Segmentation Based on Partial Instance Annotations with Pre-trained Dual-branch Network and Pseudo Label Learning18 Aug 2024
- 2024SAM-Driven Weakly Supervised Nodule Segmentation with Uncertainty-Aware Cross Teaching18 Jul 2024
- 2024Rethinking Abdominal Organ Segmentation (RAOS) in the clinical scenario: A robustness evaluation benchmark with challenging cases19 Jun 2024
- 2024ModelMix: A New Model-Mixup Strategy to Minimize Vicinal Risk across Tasks for Few-scribble based Cardiac Segmentation19 Jun 2024
- 2024DuEDL: Dual-Branch Evidential Deep Learning for Scribble-Supervised Medical Image Segmentation23 May 2024
- 2024PCLMix: Weakly Supervised Medical Image Segmentation via Pixel-Level Contrastive Learning and Dynamic Mix Augmentation10 May 2024
- 2024Beyond Pixel-Wise Supervision for Medical Image Segmentation: From Traditional Models to Foundation Models20 Apr 2024
- 2024Weakly-Supervised Learning via Multi-Lateral Decoder Branching for Tool Segmentation in Robot-Assisted Cardiovascular Catheterization11 Apr 2024
- 2024FPL+: Filtered Pseudo Label-based Unsupervised Cross-Modality Adaptation for 3D Medical Image Segmentation7 Apr 2024
- 2024Revisiting 3D Medical Scribble Supervision: Benchmarking Beyond Cardiac Segmentation19 Mar 2024
- 2024Skeleton Supervised Airway Segmentation11 Mar 2024
- 2024FedLPPA: Learning Personalized Prompt and Aggregation for Federated Weakly-supervised Medical Image Segmentation27 Feb 2024
- 2024Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentation16 Feb 2024
- 2024Semi-Mamba-UNet: Pixel-Level Contrastive and Pixel-Level Cross-Supervised Visual Mamba-based UNet for Semi-Supervised Medical Image Segmentation11 Feb 2024
- 2024ScribFormer: Transformer Makes CNN Work Better for Scribble-based Medical Image Segmentation3 Feb 2024
- 2024ProCNS: Progressive Prototype Calibration and Noise Suppression for Weakly-Supervised Medical Image Segmentation25 Jan 2024
- 2023AttenScribble: Attentive Similarity Learning for Scribble-Supervised Medical Image Segmentation11 Dec 2023
- 2023Clean Label Disentangling for Medical Image Segmentation with Noisy Labels28 Nov 2023
- 2023Versatile Medical Image Segmentation Learned from Multi-Source Datasets via Model Self-Disambiguation17 Nov 2023
- 2023ScribblePolyp: Scribble-Supervised Polyp Segmentation through Dual Consistency Alignment9 Nov 2023
- 2023Volumetric Medical Image Segmentation via Scribble Annotations and Shape Priors12 Oct 2023
- 2023Data efficient deep learning for medical image analysis: A survey10 Oct 2023
- 2023Scribble-based 3D Multiple Abdominal Organ Segmentation via Triple-branch Multi-dilated Network with Pixel- and Class-wise Consistency18 Sep 2023
50 newest of 64 All 64 (JSON)
- 2024Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentationcited by 29
- 2024Semi-Mamba-UNet: Pixel-Level Contrastive and Pixel-Level Cross-Supervised Visual Mamba-based UNet for Semi-Supervised Medical Image Segmentationcited by 20
- 2025SparseMamba-PCL: Scribble-Supervised Medical Image Segmentation via SAM-Guided Progressive Collaborative Learningcited by 2
- 2024MambaEviScrib: Mamba and Evidence-Guided Consistency Enhance CNN Robustness for Scribble-Based Weakly Supervised Ultrasound Image Segmentationcited by 1
- 2025SparseMamba-PCL: Scribble-Supervised Medical Image Segmentation via SAM-Guided Progressive Collaborative Learning3 Mar 2025
- 2024MambaEviScrib: Mamba and Evidence-Guided Consistency Enhance CNN Robustness for Scribble-Based Weakly Supervised Ultrasound Image Segmentation28 Sep 2024
- 2024Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentation16 Feb 2024
- 2024Semi-Mamba-UNet: Pixel-Level Contrastive and Pixel-Level Cross-Supervised Visual Mamba-based UNet for Semi-Supervised Medical Image Segmentation11 Feb 2024
- 2024ScribFormer: Transformer Makes CNN Work Better for Scribble-based Medical Image Segmentationcited by 24
- 2023ScribbleVC: Scribble-supervised Medical Image Segmentation with Vision-Class Embeddingcited by 23
- 2023Towards Segment Anything Model (SAM) for Medical Image Segmentation: A Surveycited by 21
- 2024Rethinking Abdominal Organ Segmentation (RAOS) in the clinical scenario: A robustness evaluation benchmark with challenging casescited by 18
- 2022PA-Seg: Learning from Point Annotations for 3D Medical Image Segmentation using Contextual Regularization and Cross Knowledge Distillationcited by 16
- 2022Scribble2D5: Weakly-Supervised Volumetric Image Segmentation via Scribble Annotationscited by 15
- 2023S2ME: Spatial-Spectral Mutual Teaching and Ensemble Learning for Scribble-supervised Polyp Segmentationcited by 15
- 2022PyMIC: A deep learning toolkit for annotation-efficient medical image segmentationcited by 14
- 2023Weakly supervised segmentation with point annotations for histopathology images via contrast-based variational modelcited by 13
- 2023Versatile Medical Image Segmentation Learned from Multi-Source Datasets via Model Self-Disambiguationcited by 12
- 2024MultiverSeg: Scalable Interactive Segmentation of Biomedical Imaging Datasets with In-Context Guidancecited by 11
- 2023DIAS: A Dataset and Benchmark for Intracranial Artery Segmentation in DSA sequencescited by 10
12 most cited of 60 All 60 (JSON)
- 2026GazeRefine: Expert Gaze as a Test-Time Prompt for Training-Free Medical Image Segmentation1 Sep 2026
- 2026Prompt-Conditioned Channel Attention for Hierarchical Feature Modulation toward Anatomy-Agnostic Segmentation20 Aug 2026
- 2026Bi-Level Collaborative Learning for Few-Shot Scribble-Supervised Medical Image Segmentation28 Jul 2026
- 2026Mutual Distillation of Dual-Foundation Models for Semi-Supervised PET/CT Segmentation14 Jun 2026
- 2026DiffSegLung: Diffusion Radiomic Distillation for Unsupervised Lung Pathology Segmentation12 May 2026
- 2026ZScribbleSeg: A comprehensive segmentation framework with modeling of efficient annotation and maximization of scribble supervision7 May 2026
- 2026PLESS: Pseudo-Label Enhancement with Spreading Scribbles for Weakly Supervised Segmentation12 Feb 2026
- 2026Scribble-Supervised Medical Image Segmentation with Dynamic Teacher Switching and Hierarchical Consistency21 Jan 2026
- 2025Needles in the Landscape: Semi-Supervised Pseudolabeling for Archaeological Site Discovery under Label Scarcity19 Oct 2025
- 2025SynMatch: Rethinking Consistency in Medical Image Segmentation with Sparse Annotations10 Aug 2025
- 2025TABNet: A Triplet Augmentation Self-Recovery Framework with Boundary-Aware Pseudo-Labels for Medical Image Segmentation3 Jul 2025
- 2025CmFNet: Cross-modal Fusion Network for Weakly-supervised Segmentation of Medical Images22 Jun 2025
12 newest of 60 All 60 (JSON)