Mumford-Shah Loss Functional for Image Segmentation with Deep Learning
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Abstract (arXiv)
Recent state-of-the-art image segmentation algorithms are mostly based on deep neural networks, thanks to their high performance and fast computation time. However, these methods are usually trained in a supervised manner, which requires large number of high quality ground-truth segmentation masks. On the other hand, classical image segmentation approaches such as level-set methods are formulated in a self-supervised manner by minimizing energy functions such as Mumford-Shah functional, so they are still useful to help generation of segmentation masks without labels. Unfortunately, these algorithms are usually computationally expensive and often have limitation in semantic segmentation. In this paper, we propose a novel loss function based on Mumford-Shah functional that can be used in deep-learning based image segmentation without or with small labeled data. This loss function is based on the observation that the softmax layer of deep neural networks has striking similarity to the characteristic function in the Mumford-Shah functional. We show that the new loss function enables semi-supervised and unsupervised segmentation. In addition, our loss function can be also used as a regularized function to enhance supervised semantic segmentation algorithms. Experimental results on multiple datasets demonstrate the effectiveness of the proposed method.
Key facts. Cited by 35 papers in the map (data through 7 Oct 2026). First posted on arXiv 5 Apr 2019.
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Citing papers per year: 2021: 3; 2022: 9; 2023: 8; 2024: 8; 2025: 5; 2026: 2.
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- 2022Scribble-Supervised Medical Image Segmentation via Dual-Branch Network and Dynamically Mixed Pseudo Labels Supervisioncited by 64
- 2022Box-supervised Instance Segmentation with Level Set Evolutioncited by 41
- 2022Overview of the HECKTOR Challenge at MICCAI 2021: Automatic Head and Neck Tumor Segmentation and Outcome Prediction in PET/CT Imagescited by 29
- 2024Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentationcited by 29
- 2024ScribFormer: Transformer Makes CNN Work Better for Scribble-based Medical Image Segmentationcited by 24
- 2023ScribbleVC: Scribble-supervised Medical Image Segmentation with Vision-Class Embeddingcited by 23
- 2022Box2Mask: Box-supervised Instance Segmentation via Level-set Evolutioncited by 22
- 2022PA-Seg: Learning from Point Annotations for 3D Medical Image Segmentation using Contextual Regularization and Cross Knowledge Distillationcited by 16
- 2022PyMIC: A deep learning toolkit for annotation-efficient medical image segmentationcited by 14
- 2023Weakly supervised segmentation with point annotations for histopathology images via contrast-based variational modelcited by 13
- 2024Ultrasound Nodule Segmentation Using Asymmetric Learning with Simple Clinical Annotationcited by 9
- 2023Scribble-based 3D Multiple Abdominal Organ Segmentation via Triple-branch Multi-dilated Network with Pixel- and Class-wise Consistencycited by 7
23 more
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- 2021Deep Superpixel Cut for Unsupervised Image Segmentationcited by 6
- 2022Annotation by Clicks: A Point-Supervised Contrastive Variance Method for Medical Semantic Segmentationcited by 4
- 2021Learning Fuzzy Clustering for SPECT/CT Segmentation via Convolutional Neural Networkscited by 3
- 2024PCLMix: Weakly Supervised Medical Image Segmentation via Pixel-Level Contrastive Learning and Dynamic Mix Augmentationcited by 3
- 2025Cell Instance Segmentation: The Devil Is in the Boundariescited by 3
- 2022Segmentation and Risk Score Prediction of Head and Neck Cancers in PET/CT Volumes with 3D U-Net and Cox Proportional Hazard Neural Networkscited by 2
- 2023Pixel-Level Clustering Network for Unsupervised Image Segmentationcited by 2
- 2025EAUWSeg: Eliminating annotation uncertainty in weakly-supervised medical image segmentationcited by 1
- 2021Deep Level Set for Box-supervised Instance Segmentation in Aerial Imagescited by 0
- 2022Estimating Appearance Models for Image Segmentation via Tensor Factorizationcited by 0
- 2023Unsupervised Cardiac Segmentation Utilizing Synthesized Images from Anatomical Labelscited by 0
- 2023Variational multichannel multiclass segmentation using unsupervised lifting with CNNscited by 0
- 2023Semi-Automated Segmentation of Geoscientific Data Using Superpixelscited by 0
- 2023AttenScribble: Attentive Similarity Learning for Scribble-Supervised Medical Image Segmentationcited by 0
- 2024Segmentation of tibiofemoral joint tissues from knee MRI using MtRA-Unet and incorporating shape information: Data from the Osteoarthritis Initiativecited by 0
- 2024DABS-LS: Deep Atlas-Based Segmentation Using Regional Level Set Self-Supervisioncited by 0
- 2024A Bayesian Approach to Weakly-supervised Laparoscopic Image Segmentationcited by 0
- 2025CmFNet: Cross-modal Fusion Network for Weakly-supervised Segmentation of Medical Imagescited by 0
- 2025Single Point, Full Mask: Velocity-Guided Level Set Evolution for End-to-End Amodal Segmentationcited by 0
- 2025TA-LSDiff:Topology-Aware Diffusion Guided by a Level Set Energy for Pancreas Segmentationcited by 0
- 2026A Unified Variational Framework for Deep Weakly Supervised Image Segmentationcited by 0
- 2026LHMCF-Net: A Learned Hyperbolic Mean Curvature Flow Network for Medical Images Segmentationcited by 0
- 2026LHMCF-Net: A Learned Hyperbolic Mean Curvature Flow Network for Medical Images Segmentation21 Aug 2026
- 2026A Unified Variational Framework for Deep Weakly Supervised Image Segmentation22 Jul 2026
- 2025TA-LSDiff:Topology-Aware Diffusion Guided by a Level Set Energy for Pancreas Segmentation2 Nov 2025
- 2025Cell Instance Segmentation: The Devil Is in the Boundaries10 Oct 2025
- 2025Single Point, Full Mask: Velocity-Guided Level Set Evolution for End-to-End Amodal Segmentation3 Aug 2025
- 2025CmFNet: Cross-modal Fusion Network for Weakly-supervised Segmentation of Medical Images22 Jun 2025
- 2025EAUWSeg: Eliminating annotation uncertainty in weakly-supervised medical image segmentation3 Jan 2025
- 2024A Bayesian Approach to Weakly-supervised Laparoscopic Image Segmentation11 Oct 2024
- 2024SAM-Driven Weakly Supervised Nodule Segmentation with Uncertainty-Aware Cross Teaching18 Jul 2024
- 2024PCLMix: Weakly Supervised Medical Image Segmentation via Pixel-Level Contrastive Learning and Dynamic Mix Augmentation10 May 2024
- 2024Ultrasound Nodule Segmentation Using Asymmetric Learning with Simple Clinical Annotation23 Apr 2024
- 2024Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentation16 Feb 2024
23 more
- 2024DABS-LS: Deep Atlas-Based Segmentation Using Regional Level Set Self-Supervision16 Feb 2024
- 2024ScribFormer: Transformer Makes CNN Work Better for Scribble-based Medical Image Segmentation3 Feb 2024
- 2024Segmentation of tibiofemoral joint tissues from knee MRI using MtRA-Unet and incorporating shape information: Data from the Osteoarthritis Initiative23 Jan 2024
- 2023AttenScribble: Attentive Similarity Learning for Scribble-Supervised Medical Image Segmentation11 Dec 2023
- 2023Pixel-Level Clustering Network for Unsupervised Image Segmentation24 Oct 2023
- 2023Scribble-based 3D Multiple Abdominal Organ Segmentation via Triple-branch Multi-dilated Network with Pixel- and Class-wise Consistency18 Sep 2023
- 2023ScribbleVC: Scribble-supervised Medical Image Segmentation with Vision-Class Embedding30 Jul 2023
- 2023Weakly supervised segmentation with point annotations for histopathology images via contrast-based variational model7 Apr 2023
- 2023Semi-Automated Segmentation of Geoscientific Data Using Superpixels20 Mar 2023
- 2023Variational multichannel multiclass segmentation using unsupervised lifting with CNNs4 Feb 2023
- 2023Unsupervised Cardiac Segmentation Utilizing Synthesized Images from Anatomical Labels15 Jan 2023
- 2022Annotation by Clicks: A Point-Supervised Contrastive Variance Method for Medical Semantic Segmentation17 Dec 2022
- 2022Box2Mask: Box-supervised Instance Segmentation via Level-set Evolution3 Dec 2022
- 2022PyMIC: A deep learning toolkit for annotation-efficient medical image segmentation19 Aug 2022
- 2022Estimating Appearance Models for Image Segmentation via Tensor Factorization16 Aug 2022
- 2022PA-Seg: Learning from Point Annotations for 3D Medical Image Segmentation using Contextual Regularization and Cross Knowledge Distillation11 Aug 2022
- 2022Box-supervised Instance Segmentation with Level Set Evolution19 Jul 2022
- 2022Scribble-Supervised Medical Image Segmentation via Dual-Branch Network and Dynamically Mixed Pseudo Labels Supervision4 Mar 2022
- 2022Segmentation and Risk Score Prediction of Head and Neck Cancers in PET/CT Volumes with 3D U-Net and Cox Proportional Hazard Neural Networks16 Feb 2022
- 2022Overview of the HECKTOR Challenge at MICCAI 2021: Automatic Head and Neck Tumor Segmentation and Outcome Prediction in PET/CT Images11 Jan 2022
- 2021Deep Level Set for Box-supervised Instance Segmentation in Aerial Images7 Dec 2021
- 2021Learning Fuzzy Clustering for SPECT/CT Segmentation via Convolutional Neural Networks17 Apr 2021
- 2021Deep Superpixel Cut for Unsupervised Image Segmentation10 Mar 2021
- 2022Scribble-Supervised Medical Image Segmentation via Dual-Branch Network and Dynamically Mixed Pseudo Labels Supervisioncited by 64
- 2022Box-supervised Instance Segmentation with Level Set Evolutioncited by 41
- 2022Overview of the HECKTOR Challenge at MICCAI 2021: Automatic Head and Neck Tumor Segmentation and Outcome Prediction in PET/CT Imagescited by 29
- 2024ScribFormer: Transformer Makes CNN Work Better for Scribble-based Medical Image Segmentationcited by 24
- 2023ScribbleVC: Scribble-supervised Medical Image Segmentation with Vision-Class Embeddingcited by 23
- 2022Box2Mask: Box-supervised Instance Segmentation via Level-set Evolutioncited by 22
- 2022PA-Seg: Learning from Point Annotations for 3D Medical Image Segmentation using Contextual Regularization and Cross Knowledge Distillationcited by 16
- 2022PyMIC: A deep learning toolkit for annotation-efficient medical image segmentationcited by 14
- 2023Weakly supervised segmentation with point annotations for histopathology images via contrast-based variational modelcited by 13
- 2024Ultrasound Nodule Segmentation Using Asymmetric Learning with Simple Clinical Annotationcited by 9
- 2023Scribble-based 3D Multiple Abdominal Organ Segmentation via Triple-branch Multi-dilated Network with Pixel- and Class-wise Consistencycited by 7
- 2024SAM-Driven Weakly Supervised Nodule Segmentation with Uncertainty-Aware Cross Teachingcited by 7
12 most cited of 34 All 34 (JSON)
- 2026LHMCF-Net: A Learned Hyperbolic Mean Curvature Flow Network for Medical Images Segmentation21 Aug 2026
- 2026A Unified Variational Framework for Deep Weakly Supervised Image Segmentation22 Jul 2026
- 2025TA-LSDiff:Topology-Aware Diffusion Guided by a Level Set Energy for Pancreas Segmentation2 Nov 2025
- 2025Cell Instance Segmentation: The Devil Is in the Boundaries10 Oct 2025
- 2025Single Point, Full Mask: Velocity-Guided Level Set Evolution for End-to-End Amodal Segmentation3 Aug 2025
- 2025CmFNet: Cross-modal Fusion Network for Weakly-supervised Segmentation of Medical Images22 Jun 2025
- 2025EAUWSeg: Eliminating annotation uncertainty in weakly-supervised medical image segmentation3 Jan 2025
- 2024A Bayesian Approach to Weakly-supervised Laparoscopic Image Segmentation11 Oct 2024
- 2024SAM-Driven Weakly Supervised Nodule Segmentation with Uncertainty-Aware Cross Teaching18 Jul 2024
- 2024PCLMix: Weakly Supervised Medical Image Segmentation via Pixel-Level Contrastive Learning and Dynamic Mix Augmentation10 May 2024
- 2024Ultrasound Nodule Segmentation Using Asymmetric Learning with Simple Clinical Annotation23 Apr 2024
- 2024DABS-LS: Deep Atlas-Based Segmentation Using Regional Level Set Self-Supervision16 Feb 2024
12 newest of 34 All 34 (JSON)