mlsanityData to 14 Oct 2026

Diaformer: Automatic Diagnosis via Symptoms Sequence Generation

arXiv 2112.10433 ↗First posted 20 Dec 2021cs.AIcited by 19

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Abstract (arXiv)

Automatic diagnosis has attracted increasing attention but remains challenging due to multi-step reasoning. Recent works usually address it by reinforcement learning methods. However, these methods show low efficiency and require taskspecific reward functions. Considering the conversation between doctor and patient allows doctors to probe for symptoms and make diagnoses, the diagnosis process can be naturally seen as the generation of a sequence including symptoms and diagnoses. Inspired by this, we reformulate automatic diagnosis as a symptoms Sequence Generation (SG) task and propose a simple but effective automatic Diagnosis model based on Transformer (Diaformer). We firstly design the symptom attention framework to learn the generation of symptom inquiry and the disease diagnosis. To alleviate the discrepancy between sequential generation and disorder of implicit symptoms, we further design three orderless training mechanisms. Experiments on three public datasets show that our model outperforms baselines on disease diagnosis by 1%, 6% and 11.5% with the highest training efficiency. Detailed analysis on symptom inquiry prediction demonstrates that the potential of applying symptoms sequence generation for automatic diagnosis.

Key facts. Cited by 19 papers in the map (data through 14 Oct 2026). Builds on 17 of its 28 references that are in the map. First posted on arXiv 20 Dec 2021.

Builds on

17 of 28 references.

References · 17

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5 more
  1. 2020Large-Scale Object Detection in the Wild from Imbalanced Multi-Labelscited by 35
  2. 2020Multi-Vehicle Routing Problems with Soft Time Windows: A Multi-Agent Reinforcement Learning Approachcited by 30
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Cited by year (2026 to 14 Oct)

Citing papers per year: 2022: 4; 2023: 3; 2024: 4; 2025: 3; 2026: 5.

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  1. 2022DDXPlus: A New Dataset For Automatic Medical Diagnosiscited by 88
  2. 2024CoD, Towards an Interpretable Medical Agent using Chain of Diagnosiscited by 43
  3. 2022On Transforming Reinforcement Learning by Transformer: The Development Trajectorycited by 36
  4. 2024Beyond Direct Diagnosis: LLM-based Multi-Specialist Agent Consultation for Automatic Diagnosiscited by 23
  5. 2022DxFormer: A Decoupled Automatic Diagnostic System Based on Decoder-Encoder Transformer with Dense Symptom Representationscited by 10
  6. 2023Medical Dialogue Generation via Dual Flow Modelingcited by 10
  7. 2022Towards Trustworthy Automatic Diagnosis Systems by Emulating Doctors' Reasoning with Deep Reinforcement Learningcited by 5
  8. 2023CoAD: Automatic Diagnosis through Symptom and Disease Collaborative Generationcited by 5
  9. 2023DDxT: Deep Generative Transformer Models for Differential Diagnosiscited by 3
  10. 2025Generalist Foundation Models Are Not Clinical Enough for Hospital Operationscited by 3
  11. 2024Automatic Differential Diagnosis using Transformer-Based Multi-Label Sequence Classificationcited by 2
  12. 2025DDO: Dual-Decision Optimization for LLM-Based Medical Consultation via Multi-Agent Collaborationcited by 2
7 more
  1. 2026MIND: Unified Inquiry and Diagnosis RL with Criteria Grounded Clinical Supports for Psychiatric Consultationcited by 1
  2. 2026From Triage to Discharge: A Survey of NLP Tasks, Methods, and Open Challenges in the Emergency Departmentcited by 1
  3. 2024Towards Knowledge-Infused Automated Disease Diagnosis Assistantcited by 0
  4. 2025GraphMed-LT: Patient-Specific Graph Memory with Latent Clinical Thought Refinement for Multi-Turn Medical Conversationscited by 0
  5. 2026COTCAgent: Preventive Consultation via Probabilistic Chain-of-Thought Completioncited by 0
  6. 2026Transformer-Enhanced Reinforcement Learning: Fundamentals and Applications in Communication Networkscited by 0
  7. 2026LLMs Anchor on Chief Complaint and Fail to Integrate Evidence in Sequential Clinical Triagecited by 0