Challenging Current Semi-Supervised Anomaly Segmentation Methods for Brain MRI
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Abstract (arXiv)
In this work, we tackle the problem of Semi-Supervised Anomaly Segmentation (SAS) in Magnetic Resonance Images (MRI) of the brain, which is the task of automatically identifying pathologies in brain images. Our work challenges the effectiveness of current Machine Learning (ML) approaches in this application domain by showing that thresholding Fluid-attenuated inversion recovery (FLAIR) MR scans provides better anomaly segmentation maps than several different ML-based anomaly detection models. Specifically, our method achieves better Dice similarity coefficients and Precision-Recall curves than the competitors on various popular evaluation data sets for the segmentation of tumors and multiple sclerosis lesions.
Key facts. Cited by 23 papers in the map (data through 7 Oct 2026). First posted on arXiv 13 Sep 2021.
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Citing papers per year: 2022: 7; 2023: 9; 2024: 4; 2025: 2; 2026: 1.
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- 2022Diffusion Models for Medical Anomaly Detectioncited by 231
- 2022What is Healthy? Generative Counterfactual Diffusion for Lesion Localizationcited by 52
- 2023Patched Diffusion Models for Unsupervised Anomaly Detection in Brain MRIcited by 45
- 2024MedIAnomaly: A comparative study of anomaly detection in medical imagescited by 25
- 2023Unsupervised Pathology Detection: A Deep Dive Into the State of the Artcited by 24
- 2023The role of noise in denoising models for anomaly detection in medical imagescited by 23
- 2022Unsupervised Anomaly Localization with Structural Feature-Autoencoderscited by 22
- 2022Constrained unsupervised anomaly segmentationcited by 19
- 2023Guided Reconstruction with Conditioned Diffusion Models for Unsupervised Anomaly Detection in Brain MRIscited by 18
- 2023Many tasks make light work: Learning to localise medical anomalies from multiple synthetic taskscited by 12
- 2022On the Pitfalls of Using the Residual Error as Anomaly Scorecited by 11
- 2023A Survey of Emerging Applications of Diffusion Probabilistic Models in MRIcited by 9
11 more
- 2024Binary Noise for Binary Tasks: Masked Bernoulli Diffusion for Unsupervised Anomaly Detectioncited by 7
- 2023Unsupervised Anomaly Detection using Aggregated Normative Diffusioncited by 4
- 2023CRADL: Contrastive Representations for Unsupervised Anomaly Detection and Localizationcited by 3
- 2023AutoPaint: A Self-Inpainting Method for Unsupervised Anomaly Detectioncited by 3
- 2024Denoising Diffusion Models for Anomaly Localization in Medical Imagescited by 3
- 2022AutoSeg -- Steering the Inductive Biases for Automatic Pathology Segmentationcited by 1
- 2022Progressive GANomaly: Anomaly detection with progressively growing GANscited by 1
- 2025Patch2Loc: Learning to Localize Patches for Unsupervised Brain Lesion Detectioncited by 1
- 2025OCSVM-Guided Representation Learning for Unsupervised Anomaly Detectioncited by 1
- 2024Rethinking Medical Anomaly Detection in Brain MRI: An Image Quality Assessment Perspectivecited by 0
- 2026MIRTO: a registration-gated, multiverse-tested evaluation protocol for unsupervised anomaly segmentation in brain MRIcited by 0
- 2026MIRTO: a registration-gated, multiverse-tested evaluation protocol for unsupervised anomaly segmentation in brain MRI1 Oct 2026
- 2025OCSVM-Guided Representation Learning for Unsupervised Anomaly Detection25 Jul 2025
- 2025Patch2Loc: Learning to Localize Patches for Unsupervised Brain Lesion Detection25 Jun 2025
- 2024Denoising Diffusion Models for Anomaly Localization in Medical Images31 Oct 2024
- 2024Rethinking Medical Anomaly Detection in Brain MRI: An Image Quality Assessment Perspective15 Aug 2024
- 2024MedIAnomaly: A comparative study of anomaly detection in medical images6 Apr 2024
- 2024Binary Noise for Binary Tasks: Masked Bernoulli Diffusion for Unsupervised Anomaly Detection18 Mar 2024
- 2023Guided Reconstruction with Conditioned Diffusion Models for Unsupervised Anomaly Detection in Brain MRIs7 Dec 2023
- 2023Unsupervised Anomaly Detection using Aggregated Normative Diffusion4 Dec 2023
- 2023A Survey of Emerging Applications of Diffusion Probabilistic Models in MRI19 Nov 2023
- 2023Many tasks make light work: Learning to localise medical anomalies from multiple synthetic tasks3 Jul 2023
- 2023AutoPaint: A Self-Inpainting Method for Unsupervised Anomaly Detection21 May 2023
11 more
- 2023Patched Diffusion Models for Unsupervised Anomaly Detection in Brain MRI7 Mar 2023
- 2023Unsupervised Pathology Detection: A Deep Dive Into the State of the Art1 Mar 2023
- 2023The role of noise in denoising models for anomaly detection in medical images19 Jan 2023
- 2023CRADL: Contrastive Representations for Unsupervised Anomaly Detection and Localization5 Jan 2023
- 2022Unsupervised Anomaly Localization with Structural Feature-Autoencoders23 Aug 2022
- 2022What is Healthy? Generative Counterfactual Diffusion for Lesion Localization25 Jul 2022
- 2022Progressive GANomaly: Anomaly detection with progressively growing GANs8 Jun 2022
- 2022Diffusion Models for Medical Anomaly Detection8 Mar 2022
- 2022Constrained unsupervised anomaly segmentation3 Mar 2022
- 2022On the Pitfalls of Using the Residual Error as Anomaly Score8 Feb 2022
- 2022AutoSeg -- Steering the Inductive Biases for Automatic Pathology Segmentation24 Jan 2022
- 2022Diffusion Models for Medical Anomaly Detectioncited by 231
- 2023Patched Diffusion Models for Unsupervised Anomaly Detection in Brain MRIcited by 45
- 2023The role of noise in denoising models for anomaly detection in medical imagescited by 23
- 2023Guided Reconstruction with Conditioned Diffusion Models for Unsupervised Anomaly Detection in Brain MRIscited by 18
- 2023A Survey of Emerging Applications of Diffusion Probabilistic Models in MRIcited by 9
- 2024Binary Noise for Binary Tasks: Masked Bernoulli Diffusion for Unsupervised Anomaly Detectioncited by 7
- 2023Unsupervised Anomaly Detection using Aggregated Normative Diffusioncited by 4
- 2024Denoising Diffusion Models for Anomaly Localization in Medical Imagescited by 3
- 2024Denoising Diffusion Models for Anomaly Localization in Medical Images31 Oct 2024
- 2024Binary Noise for Binary Tasks: Masked Bernoulli Diffusion for Unsupervised Anomaly Detection18 Mar 2024
- 2023Guided Reconstruction with Conditioned Diffusion Models for Unsupervised Anomaly Detection in Brain MRIs7 Dec 2023
- 2023Unsupervised Anomaly Detection using Aggregated Normative Diffusion4 Dec 2023
- 2023A Survey of Emerging Applications of Diffusion Probabilistic Models in MRI19 Nov 2023
- 2023Patched Diffusion Models for Unsupervised Anomaly Detection in Brain MRI7 Mar 2023
- 2023The role of noise in denoising models for anomaly detection in medical images19 Jan 2023
- 2022Diffusion Models for Medical Anomaly Detection8 Mar 2022
- 2022What is Healthy? Generative Counterfactual Diffusion for Lesion Localizationcited by 52
- 2024MedIAnomaly: A comparative study of anomaly detection in medical imagescited by 25
- 2023Unsupervised Pathology Detection: A Deep Dive Into the State of the Artcited by 24
- 2022Unsupervised Anomaly Localization with Structural Feature-Autoencoderscited by 22
- 2022Constrained unsupervised anomaly segmentationcited by 19
- 2023Many tasks make light work: Learning to localise medical anomalies from multiple synthetic taskscited by 12
- 2022On the Pitfalls of Using the Residual Error as Anomaly Scorecited by 11
- 2023CRADL: Contrastive Representations for Unsupervised Anomaly Detection and Localizationcited by 3
- 2023AutoPaint: A Self-Inpainting Method for Unsupervised Anomaly Detectioncited by 3
- 2022AutoSeg -- Steering the Inductive Biases for Automatic Pathology Segmentationcited by 1
- 2022Progressive GANomaly: Anomaly detection with progressively growing GANscited by 1
- 2025Patch2Loc: Learning to Localize Patches for Unsupervised Brain Lesion Detectioncited by 1
12 most cited of 15 All 15 (JSON)
- 2026MIRTO: a registration-gated, multiverse-tested evaluation protocol for unsupervised anomaly segmentation in brain MRI1 Oct 2026
- 2025OCSVM-Guided Representation Learning for Unsupervised Anomaly Detection25 Jul 2025
- 2025Patch2Loc: Learning to Localize Patches for Unsupervised Brain Lesion Detection25 Jun 2025
- 2024Rethinking Medical Anomaly Detection in Brain MRI: An Image Quality Assessment Perspective15 Aug 2024
- 2024MedIAnomaly: A comparative study of anomaly detection in medical images6 Apr 2024
- 2023Many tasks make light work: Learning to localise medical anomalies from multiple synthetic tasks3 Jul 2023
- 2023AutoPaint: A Self-Inpainting Method for Unsupervised Anomaly Detection21 May 2023
- 2023Unsupervised Pathology Detection: A Deep Dive Into the State of the Art1 Mar 2023
- 2023CRADL: Contrastive Representations for Unsupervised Anomaly Detection and Localization5 Jan 2023
- 2022Unsupervised Anomaly Localization with Structural Feature-Autoencoders23 Aug 2022
- 2022What is Healthy? Generative Counterfactual Diffusion for Lesion Localization25 Jul 2022
- 2022Progressive GANomaly: Anomaly detection with progressively growing GANs8 Jun 2022
12 newest of 15 All 15 (JSON)