mlsanityData to 7 Oct 2026

MammoClaw: Towards Skill-Evolving Agent Harness for Breast Cancer Mammography Analysis

arXiv 2609.31789 ↗First posted 25 Sep 2026eess.IV cs.CVcited by 0

On the map: LLM agents and tool use → Medical and scientific domain agents

Abstract (arXiv)

In this work, we explore MammoClaw, a training-free agent framework that leverages frozen MLLMs for mammography analysis. To support agentic investigation, we equip the agent with lightweight mammography-specific tools for targeted image analysis, including ROI, paired-view, and contralateral-breast examination. MammoClaw iteratively gathers evidence through these tools, while skill evolution enables non-parametric adaptation by transforming failed trajectories into reusable guidance for later runs. We evaluate the framework on BI-RADS assessment and breast density estimation tasks. In our experiments, we find that tools alone do not reliably improve performance, whereas evolved skills can improve tool-use behavior and performance in some settings. Beyond these results, MammoClaw enables transparent inspection of evidence acquisition, tool interactions, and failure modes, facilitating the analysis and auditing of agent behavior. We view this work as an exploratory study of training-free, self-evolving agentic approaches for mammography and hope it provides a concrete starting point for future work on mammography-specific tools and self-evolution mechanisms. We release our code at https://krishnakanthnakka.github.io/mammoclaw.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 19 of its 27 references that are in the map. First posted on arXiv 25 Sep 2026.

Builds on

19 of 27 references.

Closest ancestors · 4

Same direction, newest first

  1. 2026ClinSeekAgent: Automating Multimodal Evidence Seeking for Agentic Clinical Reasoning19 May
  2. 2026PhysicianBench: Evaluating LLM Agents in Real-World EHR Environments4 May
  3. 2026RadAgent: A tool-using AI agent for stepwise interpretation of chest computed tomography16 Apr
  4. 2025RadAgents: Multimodal Agentic Reasoning for Chest X-ray Interpretation with Radiologist-like Workflows24 Sep

Other references · 15

  1. 2022Training language models to follow instructions with human feedbackcited by 15,712
  2. 2024DeepSeekMath: Pushing the Limits of Mathematical Reasoning in Open Language Modelscited by 8,851
  3. 2022ReAct: Synergizing Reasoning and Acting in Language Modelscited by 8,355
  4. 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Daycited by 1,287
  5. 2023LIMA: Less Is More for Alignmentcited by 1,080
  6. 2026DeepSeek-V4: Towards Highly Efficient Million-Token Context Intelligencecited by 877
  7. 2020PathVQA: 30000+ Questions for Medical Visual Question Answeringcited by 467
  8. 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 444
  9. 2026SkillRL: Evolving Agents via Recursive Skill-Augmented Reinforcement Learningcited by 252
  10. 2026AutoSkill: Experience-Driven Lifelong Learning via Skill Self-Evolutioncited by 105
  11. 2026SkillClaw: Let Skills Evolve Collectively with Agentic Evolvercited by 76
  12. 2026MedMO: Grounding and Understanding Multimodal Large Language Model for Medical Imagescited by 12
3 more
  1. 2026MediX-R1: Open Ended Medical Reinforcement Learningcited by 7
  2. 2025Mammo-FM: Breast-specific foundational model for Integrated Mammographic Diagnosis, Prognosis, and Reportingcited by 5
  3. 2026Experience Makes Skillful: Enabling Generalizable Medical Agent Reasoning via Self-Evolving Skill Memorycited by 4

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  3. 2026Agentic Autoresearch for CT Reconstruction
  4. 2025ReX-MLE: The Autonomous Agent Benchmark for Medical Imaging Challenges
  5. 2026Evo-MedAgent: Beyond One-Shot Diagnosis with Agents That Remember, Reflect, and Improve
  6. 2025M^3Builder: A Multi-Agent System for Automated Machine Learning in Medical Imaging
  7. 2026MammoExpert: Benchmarking Chain-of-Thought Reasoning in Mammography Diagnosis
  8. 2025Simple Agents Outperform Experts in Biomedical Imaging Workflow Optimization