A Controlled Audit of Pretraining Contamination in Public Medical Vision-Language Benchmarks
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
Abstract (arXiv)
Medical vision-language models (VLMs) are evaluated on public benchmarks whose images and question-answer pairs have been freely downloadable for years, yet reported accuracy assumes these examples were absent from pretraining. We audit open VLMs on SLAKE-En, PathVQA, VQA-RAD, and an auxiliary public OmniMedVQA mirror using four detector families: image-side near-neighbour overlap against PMC-OA-beta, canonical-order exchangeability, cohort-relative Min-K%++ tail enrichment, and cross-model top-K overlap. We find measurable image-side source overlap on SLAKE-En: 19.8% of images are flagged under SigLIP-B-16 and 4.2% under SigLIP-SO400M, while out-of-domain controls produce 0/2000 flags. Manual adjudication shows same-modality, same-projection matches to different patients rather than verified pixel-level duplicates, so we interpret this as source or distributional overlap rather than confirmed per-image memorization. On the text side, Qwen2.5-VL on SLAKE-En shows a canonical-order exchangeability signal that survives ordering ablation and external non-medical baselines. On the OmniMedVQA mirror, exchangeability fires for five medical and general VLMs while BLIP-2 remains clean. In contrast, cohort-relative Min-K%++ tail enrichment and cross-model top-K overlap collapse under an external pre-domain baseline: BLIP-2 reproduces the apparent positive signals despite lacking plausible medical-VQA exposure. We conclude that these cohort-relative detectors are unreliable as standalone membership-inference signals on small medical-VLM cohorts.
Key facts. No citing papers in the map yet (data through 14 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 23 of its 24 references that are in the map. First posted on arXiv 8 Jun 2026.
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- 2023BLIP-2: Bootstrapping Language-Image Pre-training with Frozen Image Encoders and Large Language Modelscited by 6,137
- 2025Qwen2.5-VL Technical Reportcited by 5,587
- 2023Sigmoid Loss for Language Image Pre-Trainingcited by 3,109
- 2023InstructBLIP: Towards General-purpose Vision-Language Models with Instruction Tuningcited by 2,876
- 2024LLaVA-OneVision: Easy Visual Task Transfercited by 2,719
- 2016Membership Inference Attacks against Machine Learning Modelscited by 2,281
- 2020Extracting Training Data from Large Language Modelscited by 2,189
- 2021Membership Inference Attacks From First Principlescited by 878
- 2023Extracting Training Data from Diffusion Modelscited by 732
- 2021Deduplicating Training Data Makes Language Models Bettercited by 714
- 2020PathVQA: 30000+ Questions for Medical Visual Question Answeringcited by 475
- 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 449
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- 2025MedGemma Technical Reportcited by 436
- 2023NLP Evaluation in trouble: On the Need to Measure LLM Data Contamination for each Benchmarkcited by 348
- 2023Proving Test Set Contamination in Black Box Language Modelscited by 230
- 2023PMC-CLIP: Contrastive Language-Image Pre-training using Biomedical Documentscited by 212
- 2023Time Travel in LLMs: Tracing Data Contamination in Large Language Modelscited by 177
- 2024Min-K%++: Improved Baseline for Detecting Pre-Training Data from Large Language Modelscited by 103
- 2021Does BERT Pretrained on Clinical Notes Reveal Sensitive Data?cited by 93
- 2024A Vision-Language Foundation Model to Enhance Efficiency of Chest X-ray Interpretationcited by 81
- 2024Both Text and Images Leaked! A Systematic Analysis of Data Contamination in Multimodal LLMcited by 10
- 2025DyePack: Provably Flagging Test Set Contamination in LLMs Using Backdoorscited by 3
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