Do Medical Vision Language Models Actually See? A Counterfactual Grounding Framework and Hard-Negative Contrastive Training for Visually-Reliant Medical VLMs
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
Abstract (arXiv)
Large vision language models (VLMs) report strong accuracy on medical question-answering, yet it remains unclear whether they reason from visual evidence or exploit textual shortcuts. We introduce a counterfactual evaluation framework that decouples visual and textual contributions by substituting input images with controlled surrogates blank, pixel-shuffled, image-absent, and CLIP-retrieved hard negatives and derive a suite of grounding metrics including the Visual Reliance Score (VRS) and Visual Hallucination Rate (VHR). We further introduce CORAL (COntrastive Retrieval-Augmented Learning), a 7B-parameter LoRA fine-tune of Qwen2.5-VL-7B trained with a Contrastive Grounding Objective (CGO) that penalises answer invariance under hard-negative image swaps. On a paired controlled evaluation across four closed-form medical VQA benchmarks (PathVQA, PMC-VQA, SLAKE, VQA-RAD; n=400 total), CORAL improves macro accuracy by +6.7 pp (P(Delta>0)=0.988) and reduces VHR by 8.0 pp (P<0.001) over the matched Qwen2.5-VL-7B base; neither MedVLThinker RL variant achieves a significant gain on either metric. Cross-domain diagnostics further reveal that image substitution costs only <=6.5 pp on medical benchmarks versus 48-61 pp on general-domain tasks, situating the grounding gap that CGO targets. We discuss evaluation limitations openly including train/eval benchmark overlap and underpowered secondary metrics and release our framework, training code, and model weights to support reproducible grounding audits of medical VLMs.
Key facts. Cited by 7 papers in the map (data through 14 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 28 of its 37 references that are in the map. First posted on arXiv 4 Jul 2026.
Builds on
28 of 37 references.
Closest ancestors · 3
Same direction, newest first
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day1 Jun
- 2023BiomedGPT: A Generalist Vision-Language Foundation Model for Diverse Biomedical Tasks26 May
- 2023MedBLIP: Bootstrapping Language-Image Pre-training from 3D Medical Images and Texts18 May
Other references · 25
- 2022Training language models to follow instructions with human feedbackcited by 15,971
- 2020Shortcut Learning in Deep Neural Networkscited by 1,969
- 2022Learn to Explain: Multimodal Reasoning via Thought Chains for Science Question Answeringcited by 1,919
- 2023Language Models Don't Always Say What They Think: Unfaithful Explanations in Chain-of-Thought Promptingcited by 1,122
- 2023Aligning Large Multimodal Models with Factually Augmented RLHFcited by 712
- 2018Annotation Artifacts in Natural Language Inference Datacited by 671
- 2020Transformer Interpretability Beyond Attention Visualizationcited by 627
- 2022When and why vision-language models behave like bags-of-words, and what to do about it?cited by 610
- 2022Winoground: Probing Vision and Language Models for Visio-Linguistic Compositionalitycited by 529
- 2020PathVQA: 30000+ Questions for Medical Visual Question Answeringcited by 475
- 2024LLaVA-CoT: Let Vision Language Models Reason Step-by-Stepcited by 454
- 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 449
13 more
- 2017Don't Just Assume; Look and Answer: Overcoming Priors for Visual Question Answeringcited by 339
- 2025MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understandingcited by 224
- 2023Learning to Exploit Temporal Structure for Biomedical Vision-Language Processingcited by 211
- 2016Grad-CAM: Why did you say that?cited by 161
- 2016Analyzing the Behavior of Visual Question Answering Modelscited by 119
- 2023ACI-BENCH: a Novel Ambient Clinical Intelligence Dataset for Benchmarking Automatic Visit Note Generationcited by 118
- 2017FOIL it! Find One mismatch between Image and Language captioncited by 95
- 2022Reliable Visual Question Answering: Abstain Rather Than Answer Incorrectlycited by 89
- 2023Breaking Common Sense: WHOOPS! A Vision-and-Language Benchmark of Synthetic and Compositional Imagescited by 80
- 2021Human-Adversarial Visual Question Answeringcited by 57
- 2020Seeing past words: Testing the cross-modal capabilities of pretrained V&L models on counting taskscited by 34
- 2019Adversarial Regularization for Visual Question Answering: Strengths, Shortcomings, and Side Effectscited by 25
- 2026Beyond Accuracy: Evaluating Visual Grounding In Multimodal Medical Reasoningcited by 7
Built on by
Citing papers per year: 2026: 7.
7 papers.
- 2026When Do Frozen VLMs Respond to Image-Free Object-Token Edits? An Answer-Key-Free Protocol and What It Revealscited by 0
- 2026Separating Capability from Confidence: Grounded Dual-State Calibration for GRPO-Trained Medical Vision-Language Modelscited by 0
- 2026From Reward Signal to Visual Utility: A Controlled Audit of Medical VLM Post-Trainingcited by 0
- 2026BIRD: Distilling Decision Boundaries into Rationales for MLLM Adaptationcited by 0
- 2026Visual sensitivity is not claim retractability: persistence-aware credit assignment for multimodal reinforcement learningcited by 0
- 2026A Low Grounding Score Is Not an Ungrounded Judge: Identifying the Perceptibility Confound in Multimodal Oversightcited by 0
- 2026Geometric Parrots: Rule Absence vs. Rule Fragility in Spatial and Physical Reasoning for Vision-Language Modelscited by 0
- 2026Geometric Parrots: Rule Absence vs. Rule Fragility in Spatial and Physical Reasoning for Vision-Language Models12 Oct 2026
- 2026Visual sensitivity is not claim retractability: persistence-aware credit assignment for multimodal reinforcement learning29 Sep 2026
- 2026BIRD: Distilling Decision Boundaries into Rationales for MLLM Adaptation27 Sep 2026
- 2026From Reward Signal to Visual Utility: A Controlled Audit of Medical VLM Post-Training25 Sep 2026
- 2026A Low Grounding Score Is Not an Ungrounded Judge: Identifying the Perceptibility Confound in Multimodal Oversight9 Sep 2026
- 2026Separating Capability from Confidence: Grounded Dual-State Calibration for GRPO-Trained Medical Vision-Language Models6 Sep 2026
- 2026When Do Frozen VLMs Respond to Image-Free Object-Token Edits? An Answer-Key-Free Protocol and What It Reveals3 Sep 2026
Similar, not cited
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- 2025Are Large Vision Language Models Truly Grounded in Medical Images? Evidence from Italian Clinical Visual Question Answering
- 2026To Agree or To Be Right? The Grounding-Sycophancy Tradeoff in Medical Vision-Language Models
- 2025Knowing or Guessing? Robust Medical Visual Question Answering via Joint Consistency and Contrastive Learning
- 2024Fusion of Domain-Adapted Vision and Language Models for Medical Visual Question Answering
- 2026MedLVR: Latent Visual Reasoning for Reliable Medical Visual Question Answering
- 2025Benchmarking and Mitigating Sycophancy in Medical Vision Language Models
- 2026MedProb: Probing Internal Representations of Vision-Language Models for Medical Question Answering
- 2025Med-VCD: Mitigating Hallucination for Medical Large Vision Language Models through Visual Contrastive Decoding