mlsanityData to 14 Oct 2026

Beyond English benchmarks: clinical llm evaluation in Brazilian Portuguese

arXiv 2606.07853 ↗First posted 5 Jun 2026cs.CL cs.AIcited by 1

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Abstract (arXiv)

Large Language Models are transforming the support for clinical decision and their application in real scenarios. Yet, most benchmarks are conducted in English, and cross-lingual evaluation is needed to tackle the language gaps in global access. We introduce ClinicalBr, the first bilingual benchmark for clinical decision built from real Brazilian case reports. The corpus contains 2,892 cases drawn from 28 SciELO medical journals, spanning 18 specialties, and is structured as parallel Portuguese-English pairs. Each case supports four evaluation tasks: diagnosis retrieval, differential diagnosis, exam recommendation, and treatment planning. We evaluate four models: MedGemma-27B, Sabi'a-4, DeepSeek-R1, and o3-mini, across both languages. The central finding is that the Portuguese-English performance gap is task-dependent, not general. In diagnosis retrieval, English yields a consistent advantage across all models, with +7.5-12.1 accuracy points. This advantage disappears in differential diagnosis, exam recommendation, and treatment planning, where confidence intervals cross zero for most models and Portuguese completeness scores are marginally higher. Brazilian-endemic conditions proved easier than the full corpus, not harder, indicating that tropical presentations are adequately represented in current pre-training. Exam recommendation was the hardest task across all models and both languages, with F1 scores below 0.10, well below the differential diagnosis ceiling of 0.20-0.27.

Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Builds on 23 of its 39 references that are in the map. First posted on arXiv 5 Jun 2026.

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23 of 39 references.

References · 23

  1. 2024MMLU-Pro: A More Robust and Challenging Multi-Task Language Understanding Benchmarkcited by 1,848
  2. 2022Large Language Models Encode Clinical Knowledgecited by 1,830
  3. 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,356
  4. 2019PubMedQA: A Dataset for Biomedical Research Question Answeringcited by 1,288
  5. 2022MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answeringcited by 543
  6. 2025HealthBench: Evaluating Large Language Models Towards Improved Human Healthcited by 429
  7. 2023Adapted Large Language Models Can Outperform Medical Experts in Clinical Text Summarizationcited by 246
  8. 2025MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understandingcited by 224
  9. 2024Benchmarking Large Language Models on Answering and Explaining Challenging Medical Questionscited by 109
  10. 2024Towards Building Multilingual Language Model for Medicinecited by 92
  11. 2023AlpaCare:Instruction-tuned Large Language Models for Medical Applicationcited by 90
  12. 2023Better to Ask in English: Cross-Lingual Evaluation of Large Language Models for Healthcare Queriescited by 82
11 more
  1. 2025MedAgent-Pro: Towards Evidence-based Multi-modal Medical Diagnosis via Reasoning Agentic Workflowcited by 73
  2. 2025MMedAgent-RL: Optimizing Multi-Agent Collaboration for Multimodal Medical Reasoningcited by 40
  3. 2021Learning Domain-Specialised Representations for Cross-Lingual Biomedical Entity Linkingcited by 28
  4. 2025DiagnosisArena: Benchmarking Diagnostic Reasoning for Large Language Modelscited by 21
  5. 2025Advancing Conversational Diagnostic AI with Multimodal Reasoningcited by 20
  6. 2025A Case Study Exploring the Current Landscape of Synthetic Medical Record Generation with Commercial LLMscited by 13
  7. 2025BRIDGE: Benchmarking Large Language Models for Understanding Real-world Clinical Practice Textcited by 12
  8. 2024Multi-OphthaLingua: A Multilingual Benchmark for Assessing and Debiasing LLM Ophthalmological QA in LMICscited by 10
  9. 2026Sabi'a-4 Technical Reportcited by 6
  10. 2025High-Fidelity Pseudo-label Generation by Large Language Models for Training Robust Radiology Report Classifierscited by 2
  11. 2025Alvorada-Bench: Can Language Models Solve Brazilian University Entrance Exams?cited by 1

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