mlsanityData to 14 Oct 2026

Do No Harm? Hallucination and Actor-Level Abuse in Web-Deployed Medical Large Language Models

arXiv 2605.20591 ↗First posted 20 May 2026cs.CL cs.CYcited by 0

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Abstract (arXiv)

Medical large language models (LLMs), including custom medical GPTs (MedGPTs) and open-source models, are increasingly deployed on web platforms to provide clinical guidance. However, they pose risks of hallucination, policy noncompliance, and unsafe design. We conduct a large-scale assessment of 6,233 MedGPTs, evaluating a stratified sample of 1,500, together with 10 open-source LLMs. We introduce two frameworks: MedGPT-HEval for hallucination detection and an LLM-based pipeline for assessing policy violations and developer intent. Our results show that 25-30% of MedGPTs exhibit low factual accuracy, with bottom- and middle-tier models at highest risk; 33.6-54.3% violate operational thresholds, and 57.06% of Action-enabled models lack adequate privacy disclosures. Compared with open-source models, MedGPTs achieve higher factual accuracy and semantic alignment, though open-source models are more stable. These results reveal systemic gaps in hallucination and compliance, highlighting the need for multi-metric evaluation and stronger safeguards. We release HAA-MedGPT, a structured dataset that supports future research on the safety of web-facing medical LLMs.

Key facts. No citing papers in the map yet (data through 14 Oct 2026). Builds on 35 of its 57 references that are in the map. First posted on arXiv 20 May 2026.

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References · 35

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23 more
  1. 2023A Stitch in Time Saves Nine: Detecting and Mitigating Hallucinations of LLMs by Validating Low-Confidence Generationcited by 206
  2. 2023A Survey of Large Language Models for Healthcare: from Data, Technology, and Applications to Accountability and Ethicscited by 163
  3. 2023Med-HALT: Medical Domain Hallucination Test for Large Language Modelscited by 157
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  12. 2024A Survey on Medical Large Language Models: Technology, Application, Trustworthiness, and Future Directionscited by 34
  13. 2023Creating Trustworthy LLMs: Dealing with Hallucinations in Healthcare AIcited by 33
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  16. 2024MedHalu: Hallucinations in Responses to Healthcare Queries by Large Language Modelscited by 21
  17. 2024Aloe: A Family of Fine-tuned Open Healthcare LLMscited by 20
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  21. 2024GPTs Window Shopping: An analysis of the Landscape of Custom ChatGPT Modelscited by 4
  22. 2025Theoretical Foundations and Mitigation of Hallucination in Large Language Modelscited by 3
  23. 2024Listening to Patients: A Framework of Detecting and Mitigating Patient Misreport for Medical Dialogue Generationcited by 2

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