mlsanityData to 7 Oct 2026

MedLoc-R1: Performance-Aware Curriculum Reward Scheduling for GRPO-Based Medical Visual Grounding

arXiv 2603.28120 ↗First posted 30 Mar 2026cs.CVcited by 0

On the map: LLM reasoning → Clinical and biomedical applications

Abstract (arXiv)

Medical visual grounding serves as a crucial foundation for fine-grained multimodal reasoning and interpretable clinical decision support. Despite recent advances in reinforcement learning (RL) for grounding tasks, existing approaches such as Group Relative Policy Optimization~(GRPO) suffer from severe reward sparsity when directly applied to medical images, primarily due to the inherent difficulty of localizing small or ambiguous regions of interest, which is further exacerbated by the rigid and suboptimal nature of fixed IoU-based reward schemes in RL. This leads to vanishing policy gradients and stagnated optimization, particularly during early training. To address this challenge, we propose MedLoc-R1, a performance-aware reward scheduling framework that progressively tightens the reward criterion in accordance with model readiness. MedLoc-R1 introduces a sliding-window performance tracker and a multi-condition update rule that automatically adjust the reward schedule from dense, easily obtainable signals to stricter, fine-grained localization requirements, while preserving the favorable properties of GRPO without introducing auxiliary networks or additional gradient paths. Experiments on three medical visual grounding benchmarks demonstrate that MedLoc-R1 consistently improves both localization accuracy and training stability over GRPO-based baselines. Our framework offers a general, lightweight, and effective solution for RL-based grounding in high-stakes medical applications. Code & checkpoints are available at hyperlinkhttps://github.com/MembrAI/MedLoc-R1.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 31 of its 42 references that are in the map. First posted on arXiv 30 Mar 2026.

Builds on

31 of 42 references.

Closest ancestors · 4

Same direction, newest first

  1. 2026Improving Medical Visual Reinforcement Fine-Tuning via Perception and Reasoning Augmentation11 Feb
  2. 2025MedGround-R1: Advancing Medical Image Grounding via Spatial-Semantic Rewarded Group Relative Policy Optimization1 Jul
  3. 2025Improving Medical Reasoning with Curriculum-Aware Reinforcement Learning25 May
  4. 2025Med-R1: Reinforcement Learning for Generalizable Medical Reasoning in Vision-Language Models18 Mar

Other references · 27

  1. 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,456
  2. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
  3. 2022Training language models to follow instructions with human feedbackcited by 15,712
  4. 2017Proximal Policy Optimization Algorithmscited by 14,441
  5. 2024DeepSeekMath: Pushing the Limits of Mathematical Reasoning in Open Language Modelscited by 8,851
  6. 2023Direct Preference Optimization: Your Language Model is Secretly a Reward Modelcited by 7,916
  7. 2023Grounding DINO: Marrying DINO with Grounded Pre-Training for Open-Set Object Detectioncited by 3,274
  8. 2025DAPO: An Open-Source LLM Reinforcement Learning System at Scalecited by 2,678
  9. 2018UNet++: A Nested U-Net Architecture for Medical Image Segmentationcited by 1,518
  10. 2024LlamaFactory: Unified Efficient Fine-Tuning of 100+ Language Modelscited by 1,442
  11. 2017A Survey on Deep Learning in Medical Image Analysiscited by 1,182
  12. 2021Grounded Language-Image Pre-trainingcited by 1,147
15 more
  1. 2025VLM-R1: A Stable and Generalizable R1-style Large Vision-Language Modelcited by 515
  2. 2025Visual-RFT: Visual Reinforcement Fine-Tuningcited by 501
  3. 2020Curriculum Learning for Reinforcement Learning Domains: A Framework and Surveycited by 350
  4. 2018Human-level performance in first-person multiplayer games with population-based deep reinforcement learningcited by 260
  5. 2017Reverse Curriculum Generation for Reinforcement Learningcited by 185
  6. 2022Medical Image Understanding with Pretrained Vision Language Models: A Comprehensive Studycited by 66
  7. 2022Reinforcement Learning with Sparse Rewards using Guidance from Offline Demonstrationcited by 54
  8. 2025One RL to See Them All: Visual Triple Unified Reinforcement Learningcited by 29
  9. 2025VL-Cogito: Progressive Curriculum Reinforcement Learning for Advanced Multimodal Reasoningcited by 26
  10. 2018BaRC: Backward Reachability Curriculum for Robotic Reinforcement Learningcited by 21
  11. 2025TinyR1-32B-Preview: Boosting Accuracy with Branch-Merge Distillationcited by 12
  12. 2021Style Curriculum Learning for Robust Medical Image Segmentationcited by 6
  13. 2024Curriculum Prompting Foundation Models for Medical Image Segmentationcited by 6
  14. 2025Prompt as Knowledge Bank: Boost Vision-language model via Structural Representation for zero-shot medical detectioncited by 3
  15. 2025iDPA: Instance Decoupled Prompt Attention for Incremental Medical Object Detectioncited by 2

Built on by

Not cited yet.

Similar, not cited

Close in wording, no citation either way

  1. 2025MedGRPO: Multi-Task Reinforcement Learning for Heterogeneous Medical Video Understanding
  2. 2025MedReasoner: Reinforcement Learning Drives Reasoning Grounding from Clinical Thought to Pixel-Level Precision
  3. 2025Ground-R1: Incentivizing Grounded Visual Reasoning via Reinforcement Learning
  4. 2026Beyond Accuracy: Evaluating Visual Grounding In Multimodal Medical Reasoning
  5. 2025Benchmark Success, Clinical Failure: When Reinforcement Learning Optimizes for Benchmarks, Not Patients
  6. 2026LocAnyMed: Vision-Language Grounding for Multimodal Medical Images
  7. 2025MedEyes: Learning Dynamic Visual Focus for Medical Progressive Diagnosis
  8. 2025Adaptive Reinforcement for Open-ended Medical Reasoning via Semantic-Guided Reward Collapse Mitigation