mlsanityData to 7 Oct 2026

Agentic retrieval-augmented reasoning reshapes collective reliability under model variability in radiology question answering

arXiv 2603.06271 ↗First posted 6 Mar 2026cs.LG cs.AIcited by 1

On the map: LLM reasoning → Clinical and biomedical applications

also in 2 more
Abstract (arXiv)

Agentic retrieval-augmented reasoning pipelines are increasingly used to structure how large language models (LLMs) incorporate external evidence in clinical decision support. These systems iteratively retrieve curated domain knowledge and synthesize it into structured reports before answer selection. Although such pipelines can improve performance, their impact on reliability under model variability remains unclear. In real-world deployment, heterogeneous models may align, diverge, or synchronize errors in ways not captured by accuracy. We evaluated 34 LLMs on 169 expert-curated publicly available radiology questions, comparing zero-shot inference with a radiology-specific multi-step agentic retrieval condition in which all models received identical structured evidence reports derived from curated radiology knowledge. Agentic inference reduced inter-model decision dispersion (median entropy 0.48 vs. 0.13) and increased robustness of correctness across models (mean 0.74 vs. 0.81). Majority consensus also increased overall (P<0.001). Consensus strength and robust correctness remained correlated under both strategies (rho=0.88 for zero-shot; rho=0.87 for agentic), although high agreement did not guarantee correctness. Response verbosity showed no meaningful association with correctness. Among 572 incorrect outputs, 72% were associated with moderate or high clinically assessed severity, although inter-rater agreement was low (kappa=0.02). Agentic retrieval therefore was associated with more concentrated decision distributions, stronger consensus, and higher cross-model robustness of correctness. These findings suggest that evaluating agentic systems through accuracy or agreement alone may not always be sufficient, and that complementary analyses of stability, cross-model robustness, and potential clinical impact are needed to characterize reliability under model variability.

Key facts. Cited by 1 paper in the map (data through 7 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 33 of its 81 references that are in the map. First posted on arXiv 6 Mar 2026.

Builds on

33 of 81 references.

Closest ancestors · 1

Same direction, newest first

  1. 2025Multi-step retrieval and reasoning improves radiology question answering with large language models1 Aug

Other references · 32

  1. 2023GPT-4 Technical Reportcited by 18,132
  2. 2024The Llama 3 Herd of Modelscited by 14,192
  3. 2023LLaMA: Open and Efficient Foundation Language Modelscited by 13,958
  4. 2020Retrieval-Augmented Generation for Knowledge-Intensive NLP Taskscited by 9,160
  5. 2022ReAct: Synergizing Reasoning and Acting in Language Modelscited by 8,355
  6. 2025Qwen3 Technical Reportcited by 8,195
  7. 2025DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learningcited by 6,146
  8. 2023Qwen Technical Reportcited by 3,273
  9. 2015Neural Machine Translation of Rare Words with Subword Unitscited by 2,898
  10. 2019Benchmarking Neural Network Robustness to Common Corruptions and Perturbationscited by 2,857
  11. 2020Shortcut Learning in Deep Neural Networkscited by 1,928
  12. 2022Large Language Models Encode Clinical Knowledgecited by 1,807
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  1. 2017Understanding Black-box Predictions via Influence Functionscited by 1,714
  2. 2025Gemma 3 Technical Reportcited by 1,686
  3. 2019Can You Trust Your Model's Uncertainty? Evaluating Predictive Uncertainty Under Dataset Shiftcited by 1,274
  4. 2023Language Models Don't Always Say What They Think: Unfaithful Explanations in Chain-of-Thought Promptingcited by 1,081
  5. 2019Attention is not Explanationcited by 916
  6. 2024Gemma: Open Models Based on Gemini Research and Technologycited by 889
  7. 2026GLM-5: from Vibe Coding to Agentic Engineeringcited by 502
  8. 2020Underspecification Presents Challenges for Credibility in Modern Machine Learningcited by 488
  9. 2026Kimi K2.5: Visual Agentic Intelligencecited by 449
  10. 2025MedGemma Technical Reportcited by 398
  11. 2020Does the Whole Exceed its Parts? The Effect of AI Explanations on Complementary Team Performancecited by 396
  12. 2021Revisiting the Calibration of Modern Neural Networkscited by 387
  13. 2023Faithful Chain-of-Thought Reasoningcited by 285
  14. 2025MiniMax-M1: Scaling Test-Time Compute Efficiently with Lightning Attentioncited by 248
  15. 2026MiMo-V2-Flash Technical Reportcited by 163
  16. 2024Med42-v2: A Suite of Clinical LLMscited by 89
  17. 2024MedVersa: A Generalist Foundation Model for Medical Image Interpretationcited by 37
  18. 2023Large Language Models Streamline Automated Machine Learning for Clinical Studiescited by 24
  19. 2024RadioRAG: Online Retrieval-augmented Generation for Radiology Question Answeringcited by 10
  20. 2025From large language models to multimodal AI: A scoping review on the potential of generative AI in medicinecited by 5

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