mlsanityData to 7 Oct 2026

How Well Do Multimodal Models Reason on ECG Signals?

arXiv 2603.00312 ↗First posted 27 Feb 2026cs.AI cs.LGcited by 2

On the map: LLM reasoning → Clinical and biomedical applications

Abstract (arXiv)

While multimodal large language models offer a promising solution to the "black box" nature of health AI by generating interpretable reasoning traces, verifying the validity of these traces remains a critical challenge. Existing evaluation methods are either unscalable, relying on manual clinician review, or superficial, utilizing proxy metrics (e.g. QA) that fail to capture the semantic correctness of clinical logic. In this work, we introduce a reproducible framework for evaluating reasoning in ECG signals. We propose decomposing reasoning into two distinct, components: (i) Perception, the accurate identification of patterns within the raw signal, and (ii) Deduction, the logical application of domain knowledge to those patterns. To evaluate Perception, we employ an agentic framework that generates code to empirically verify the temporal structures described in the reasoning trace. To evaluate Deduction, we measure the alignment of the model's logic against a structured database of established clinical criteria in a retrieval-based approach. This dual-verification method enables the scalable assessment of "true" reasoning capabilities.

Key facts. Cited by 2 papers in the map (data through 7 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 14 of its 48 references that are in the map. First posted on arXiv 27 Feb 2026.

Builds on

14 of 48 references.

References · 14

  1. 2023Gemini: A Family of Highly Capable Multimodal Modelscited by 810
  2. 2023Measuring Faithfulness in Chain-of-Thought Reasoningcited by 668
  3. 2025Humanity's Last Examcited by 467
  4. 2025Towards a Science of Scaling Agent Systemscited by 125
  5. 2024ChatTS: Aligning Time Series with LLMs via Synthetic Data for Enhanced Understanding and Reasoningcited by 95
  6. 2023Can ChatGPT Defend its Belief in Truth? Evaluating LLM Reasoning via Debatecited by 92
  7. 2025DataSciBench: An LLM Agent Benchmark for Data Sciencecited by 53
  8. 2023Beyond Chain-of-Thought, Effective Graph-of-Thought Reasoning in Language Modelscited by 51
  9. 2025SensorLM: Learning the Language of Wearable Sensorscited by 44
  10. 2025GEM: Empowering MLLM for Grounded ECG Understanding with Time Series and Imagescited by 35
  11. 2025OpenTSLM: Time-Series Language Models for Reasoning over Multivariate Medical Text- and Time-Series Datacited by 30
  12. 2025The Anatomy of a Personal Health Agentcited by 15
2 more
  1. 2024MedualTime: A Dual-Adapter Language Model for Medical Time Series-Text Multimodal Learningcited by 11
  2. 2025Time2Lang: Bridging Time-Series Foundation Models and Large Language Models for Health Sensing Beyond Promptingcited by 7

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2026: 2.

2 papers.

Similar, not cited

Close in wording, no citation either way

  1. 2026ECG-Reasoning-Benchmark: A Benchmark for Evaluating Clinical Reasoning Capabilities in ECG Interpretation
  2. 2026CARE-ECG: Causal Agent-based Reasoning for Explainable and Counterfactual ECG Interpretation
  3. 2026ECG-R1: Protocol-Guided and Modality-Agnostic MLLM for Reliable ECG Interpretation
  4. 2026Reasoning Before Diagnosis: Physician-Inspired Structured Thinking for ECG Classification
  5. 2025MedMMV: A Controllable Multimodal Multi-Agent Framework for Reliable and Verifiable Clinical Reasoning
  6. 2025A Medical Multimodal Diagnostic Framework Integrating Vision-Language Models and Logic Tree Reasoning
  7. 2024De-biased Multimodal Electrocardiogram Analysis
  8. 2025Agentic Temporal Graph of Reasoning with Multimodal Language Models: A Potential AI Aid to Healthcare