mlsanityData to 14 Oct 2026

A Medical Multimodal Diagnostic Framework Integrating Vision-Language Models and Logic Tree Reasoning

arXiv 2512.21583 ↗First posted 25 Dec 2025cs.AIcited by 1

On the map: LLM reasoning → Clinical and biomedical applications

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Abstract (arXiv)

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce hallucinations or inconsistent chains of thought, limiting clinical trust. We propose a diagnostic framework built upon LLaVA that combines vision-language alignment with logic-regularized reasoning. The system includes an input encoder for text and images, a projection module for cross-modal alignment, a reasoning controller that decomposes diagnostic tasks into steps, and a logic tree generator that assembles stepwise premises into verifiable conclusions. Evaluations on MedXpertQA and other benchmarks show that our method improves diagnostic accuracy and yields more interpretable reasoning traces on multimodal tasks, while remaining competitive on text-only settings. These results suggest a promising step toward trustworthy multimodal medical AI.

Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 22 of its 36 references that are in the map. First posted on arXiv 25 Dec 2025.

Builds on

22 of 36 references.

Closest ancestors · 1

Same direction, newest first

  1. 2025MedLA: A Logic-Driven Multi-Agent Framework for Complex Medical Reasoning with Large Language Models28 Sep

Other references · 21

  1. 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,744
  2. 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 30,186
  3. 2023LLaMA: Open and Efficient Foundation Language Modelscited by 14,132
  4. 2022Chain-of-Thought Prompting Elicits Reasoning in Large Language Modelscited by 12,459
  5. 2023Visual Instruction Tuningcited by 7,869
  6. 2025DAPO: An Open-Source LLM Reinforcement Learning System at Scalecited by 2,810
  7. 2022Survey of Hallucination in Natural Language Generationcited by 2,075
  8. 2022Large Language Models Encode Clinical Knowledgecited by 1,830
  9. 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Daycited by 1,305
  10. 2019PubMedQA: A Dataset for Biomedical Research Question Answeringcited by 1,288
  11. 2023BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairscited by 520
  12. 2020PathVQA: 30000+ Questions for Medical Visual Question Answeringcited by 475
9 more
  1. 2023Med-Flamingo: a Multimodal Medical Few-shot Learnercited by 392
  2. 2025MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understandingcited by 224
  3. 2024MDAgents: An Adaptive Collaboration of LLMs for Medical Decision-Makingcited by 163
  4. 2025HealthGPT: A Medical Large Vision-Language Model for Unifying Comprehension and Generation via Heterogeneous Knowledge Adaptationcited by 114
  5. 2024Improving Retrieval-Augmented Generation in Medicine with Iterative Follow-up Questionscited by 54
  6. 2022Boosting Novel Category Discovery Over Domains with Soft Contrastive Learning and All-in-One Classifiercited by 18
  7. 2025UMIT: Unifying Medical Imaging Tasks via Vision-Language Modelscited by 12
  8. 2022EVNet: An Explainable Deep Network for Dimension Reductioncited by 8
  9. 2023DiffAug: Enhance Unsupervised Contrastive Learning with Domain-Knowledge-Free Diffusion-based Data Augmentationcited by 7

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Cited by year (2026 to 14 Oct)

Citing papers per year: 2026: 1.

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  1. 2025MedMMV: A Controllable Multimodal Multi-Agent Framework for Reliable and Verifiable Clinical Reasoning
  2. 2025MedAtlas: Evaluating LLMs for Multi-Round, Multi-Task Medical Reasoning Across Diverse Imaging Modalities and Clinical Text
  3. 2025Medical Reasoning in the Era of LLMs: A Systematic Review of Enhancement Techniques and Applications
  4. 2026Toward Guarantees for Clinical Reasoning in Vision Language Models via Formal Verification
  5. 2026Towards Responsible Multimodal Medical Reasoning via Context-Aligned Vision-Language Models
  6. 2025Architecting Clinical Collaboration: Multi-Agent Reasoning Systems for Multimodal Medical VQA
  7. 2026OpenMedReason: Scientific Reasoning Supervision for Medical Vision-Language Models
  8. 2025Med-CMR: A Fine-Grained Benchmark Integrating Visual Evidence and Clinical Logic for Medical Complex Multimodal Reasoning