MedCEG: Reinforcing Verifiable Medical Reasoning with Critical Evidence Graph
On the map: LLM reasoning → Clinical and biomedical applications
Abstract (arXiv)
Large language models with reasoning capabilities have demonstrated impressive performance across a wide range of domains. In clinical applications, a transparent, step-by-step reasoning process provides physicians with strong evidence to support decision-making. While reinforcement learning has effectively enhanced reasoning performance in medical contexts, the clinical reliability of these reasoning processes remains limited because their accuracy and validity are often overlooked during training. To address this gap, we propose MedCEG, a framework that augments medical language models with clinically valid reasoning pathways by explicitly supervising the reasoning process through a Critical Evidence Graph (CEG). We curate a dataset of challenging clinical cases and algorithmically construct a CEG for each sample to represent a high-quality verifiable reasoning pathway. To guide the reasoning process, we introduce a Clinical Reasoning Procedure Reward, which evaluates Node Coverage, Structural Correctness, and Chain Completeness, thereby providing a holistic assessment of reasoning quality. Experimental results show that MedCEG surpasses existing methods in performance while producing clinically valid reasoning chains, representing a solid advancement in reliable medical AI reasoning. The code and models are available at https://github.com/LinjieMu/MedCEG.
Key facts. Cited by 4 papers in the map (data through 14 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 23 of its 44 references that are in the map. First posted on arXiv 15 Dec 2025.
Builds on
23 of 44 references.
Closest ancestors · 7
Same direction, newest first
- 2025Beyond Distillation: Pushing the Limits of Medical LLM Reasoning with Minimalist Rule-Based RL23 May
- 2025DiagnosisArena: Benchmarking Diagnostic Reasoning for Large Language Models20 May
- 2025MedCaseReasoning: Evaluating and learning diagnostic reasoning from clinical case reports16 May
- 2025MedReason: Eliciting Factual Medical Reasoning Steps in LLMs via Knowledge Graphs1 Apr
- 2025MedS3: Towards Medical Slow Thinking with Self-Evolved Soft Dual-sided Process Supervision21 Jan
- 2025O1 Replication Journey -- Part 3: Inference-time Scaling for Medical Reasoning11 Jan
- 2024HuatuoGPT-o1, Towards Medical Complex Reasoning with LLMs25 Dec
Other references · 16
- 2017Proximal Policy Optimization Algorithmscited by 15,215
- 2024DeepSeekMath: Pushing the Limits of Mathematical Reasoning in Open Language Modelscited by 9,379
- 2025Qwen3 Technical Reportcited by 8,820
- 2020Measuring Massive Multitask Language Understandingcited by 7,963
- 2025DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learningcited by 6,330
- 2024Qwen2.5 Technical Reportcited by 4,942
- 2025Gemini 2.5: Pushing the Frontier with Advanced Reasoning, Multimodality, Long Context, and Next Generation Agentic Capabilitiescited by 3,796
- 2024HybridFlow: A Flexible and Efficient RLHF Frameworkcited by 2,057
- 2025Gemma 3 Technical Reportcited by 1,824
- 2024LlamaFactory: Unified Efficient Fine-Tuning of 100+ Language Modelscited by 1,464
- 2025gpt-oss-120b & gpt-oss-20b Model Cardcited by 1,386
- 2025Group Sequence Policy Optimizationcited by 835
4 more
- 2024DeepSeek-V3 Technical Reportcited by 811
- 2025MedGemma Technical Reportcited by 436
- 2025Medical Hallucinations in Foundation Models and Their Impact on Healthcarecited by 93
- 2025Language Models Improve When Pretraining Data Matches Target Taskscited by 19
Built on by
Citing papers per year: 2026: 4.
4 papers.
- 2026EHRWorld: A Patient-Centric Medical World Model for Long-Horizon Clinical Trajectoriescited by 19
- 2026MedPRMBench: A Fine-grained Benchmark for Process Reward Models in Medical Reasoningcited by 2
- 2026Breaking Failure Cascades: Step-Aware Reinforcement Learning for Medical Multimodal Reasoningcited by 2
- 2026VeriGraph: Towards Verifiable Data-Analytic Agentscited by 0
- 2026Breaking Failure Cascades: Step-Aware Reinforcement Learning for Medical Multimodal Reasoning30 Jun 2026
- 2026VeriGraph: Towards Verifiable Data-Analytic Agents15 Jun 2026
- 2026MedPRMBench: A Fine-grained Benchmark for Process Reward Models in Medical Reasoning19 Apr 2026
- 2026EHRWorld: A Patient-Centric Medical World Model for Long-Horizon Clinical Trajectories3 Feb 2026
Similar, not cited
Close in wording, no citation either way
- 2026Scaling Medical Reasoning Verification via Tool-Integrated Reinforcement Learning
- 2026Medical Reasoning with Large Language Models: A Survey and MR-Bench
- 2025Med-PRM: Medical Reasoning Models with Stepwise, Guideline-verified Process Rewards
- 2024Critique of Impure Reason: Unveiling the reasoning behaviour of medical Large Language Models
- 2025Fleming-R1: Toward Expert-Level Medical Reasoning via Reinforcement Learning
- 2025Medical Reasoning in the Era of LLMs: A Systematic Review of Enhancement Techniques and Applications
- 2026Eliciting Medical Reasoning with Knowledge-enhanced Data Synthesis: A Semi-Supervised Reinforcement Learning Approach
- 2025Automating Expert-Level Medical Reasoning Evaluation of Large Language Models