mlsanityData to 14 Oct 2026

Towards Self-Supervised Foundation Models for Critical Care Time Series

arXiv 2509.19885 ↗First posted 24 Sep 2025cs.LG cs.AIcited by 0

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Abstract (arXiv)

Domain-specific foundation models for healthcare have expanded rapidly in recent years, yet foundation models for critical care time series remain relatively underexplored due to the limited size and availability of datasets. In this work, we introduce an early-stage pre-trained foundation model for critical care time-series based on the Bi-Axial Transformer (BAT), trained on pooled electronic health record datasets. We demonstrate effective transfer learning by fine-tuning the model on a dataset distinct from the training sources for mortality prediction, where it outperforms supervised baselines, particularly for small datasets (<5,000). These contributions highlight the potential of self-supervised foundation models for critical care times series to support generalizable and robust clinical applications in resource-limited settings.

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References · 24

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12 more
  1. 2023EHRSHOT: An EHR Benchmark for Few-Shot Evaluation of Foundation Modelscited by 105
  2. 2021Self-Supervised Transformer for Sparse and Irregularly Sampled Multivariate Clinical Time-Seriescited by 96
  3. 2023Foundation Model for Endoscopy Video Analysis via Large-scale Self-supervised Pre-traincited by 75
  4. 2023Learning Multi-modal Representations by Watching Hundreds of Surgical Video Lecturescited by 68
  5. 2024A Comprehensive Survey of Foundation Models in Medicinecited by 56
  6. 2021HiRID-ICU-Benchmark -- A Comprehensive Machine Learning Benchmark on High-resolution ICU Datacited by 39
  7. 2024BrainSegFounder: Towards 3D Foundation Models for Neuroimage Segmentationcited by 39
  8. 2024EHRMamba: Towards Generalizable and Scalable Foundation Models for Electronic Health Recordscited by 32
  9. 2023Yet Another ICU Benchmark: A Flexible Multi-Center Framework for Clinical MLcited by 29
  10. 2023DuETT: Dual Event Time Transformer for Electronic Health Recordscited by 17
  11. 2024EMIT- Event-Based Masked Auto Encoding for Irregular Time Seriescited by 5
  12. 2025Bi-Axial Transformers: Addressing the Increasing Complexity of EHR Classificationcited by 2

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