Retrieval-Augmented VLMs for Multimodal Melanoma Diagnosis
On the map: Retrieval-augmented generation → Medical and biomedical RAG
Abstract (arXiv)
Accurate and early diagnosis of malignant melanoma is critical for improving patient outcomes. While convolutional neural networks (CNNs) have shown promise in dermoscopic image analysis, they often neglect clinical metadata and require extensive preprocessing. Vision-language models (VLMs) offer a multimodal alternative but struggle to capture clinical specificity when trained on general-domain data. To address this, we propose a retrieval-augmented VLM framework that incorporates semantically similar patient cases into the diagnostic prompt. Our method enables informed predictions without fine-tuning and significantly improves classification accuracy and error correction over conventional baselines. These results demonstrate that retrieval-augmented prompting provides a robust strategy for clinical decision support.
Key facts. No citing papers in the map yet (data through 14 Oct 2026). Placed in Medical and biomedical RAG, one of 15 directions in Retrieval-augmented generation. Builds on 14 of its 23 references that are in the map. First posted on arXiv 10 Sep 2025.
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14 of 23 references.
References · 14
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- 2025Pathology Report Generation and Multimodal Representation Learning for Cutaneous Melanocytic Lesions
- 2026How Medical VLMs Underutilize Their Vision Encoders: A Dermatology Perspective
- 2025MM-Skin: Enhancing Dermatology Vision-Language Model with an Image-Text Dataset Derived from Textbooks
- 2025Grounding Multimodal Large Language Models with Quantitative Skin Attributes: A Retrieval Study
- 2025Breast Cancer VLMs: Clinically Practical Vision-Language Train-Inference Models
- 2024Knowledge-grounded Adaptation Strategy for Vision-language Models: Building Unique Case-set for Screening Mammograms for Residents Training
- 2026CNNs, Transformers, Hybrid, and Vision Language Models for Skin Cancer Detection
- 2025Taming Vision-Language Models for Medical Image Analysis: A Comprehensive Review