DrVD-Bench: Do Vision-Language Models Reason Like Human Doctors in Medical Image Diagnosis?
On the map: LLM reasoning → Clinical and biomedical applications
Abstract (arXiv)
Vision-language models (VLMs) exhibit strong zero-shot generalization on natural images and show early promise in interpretable medical image analysis. However, existing benchmarks do not systematically evaluate whether these models truly reason like human clinicians or merely imitate superficial patterns. To address this gap, we propose DrVD-Bench, the first multimodal benchmark for clinical visual reasoning. DrVD-Bench consists of three modules: Visual Evidence Comprehension, Reasoning Trajectory Assessment, and Report Generation Evaluation, comprising a total of 7,789 image-question pairs. Our benchmark covers 20 task types, 17 diagnostic categories, and five imaging modalities-CT, MRI, ultrasound, radiography, and pathology. DrVD-Bench is explicitly structured to reflect the clinical reasoning workflow from modality recognition to lesion identification and diagnosis. We benchmark 19 VLMs, including general-purpose and medical-specific, open-source and proprietary models, and observe that performance drops sharply as reasoning complexity increases. While some models begin to exhibit traces of human-like reasoning, they often still rely on shortcut correlations rather than grounded visual understanding. DrVD-Bench offers a rigorous and structured evaluation framework to guide the development of clinically trustworthy VLMs.
Key facts. Cited by 10 papers in the map (data through 14 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 36 of its 93 references that are in the map. First posted on arXiv 30 May 2025.
Builds on
36 of 93 references.
Closest ancestors · 1
Same direction, newest first
- 2025Med-R1: Reinforcement Learning for Generalizable Medical Reasoning in Vision-Language Models18 Mar
Other references · 35
- 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,744
- 2025Qwen2.5-VL Technical Reportcited by 5,587
- 2019BERTScore: Evaluating Text Generation with BERTcited by 5,512
- 2024GPT-4o System Cardcited by 4,588
- 2023Improved Baselines with Visual Instruction Tuningcited by 4,418
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Daycited by 1,305
- 2024OpenAI o1 System Cardcited by 1,244
- 2024ChatGLM: A Family of Large Language Models from GLM-130B to GLM-4 All Toolscited by 1,121
- 2024Are We on the Right Way for Evaluating Large Vision-Language Models?cited by 914
- 2025Janus-Pro: Unified Multimodal Understanding and Generation with Data and Model Scalingcited by 812
- 2024DeepSeek-V3 Technical Reportcited by 811
- 2024Phi-4 Technical Reportcited by 711
23 more
- 2018Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challengecited by 511
- 2022AMOS: A Large-Scale Abdominal Multi-Organ Benchmark for Versatile Medical Image Segmentationcited by 351
- 2023PMC-VQA: Visual Instruction Tuning for Medical Visual Question Answeringcited by 338
- 2023Reasoning or Reciting? Exploring the Capabilities and Limitations of Language Models Through Counterfactual Taskscited by 246
- 2023HuatuoGPT, towards Taming Language Model to Be a Doctorcited by 214
- 2024HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scalecited by 200
- 2023Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Datacited by 179
- 2024Vision-Language Models for Medical Report Generation and Visual Question Answering: A Reviewcited by 125
- 2025HealthGPT: A Medical Large Vision-Language Model for Unifying Comprehension and Generation via Heterogeneous Knowledge Adaptationcited by 114
- 2024Rethinking Interpretability in the Era of Large Language Modelscited by 111
- 2025MedSAM2: Segment Anything in 3D Medical Images and Videoscited by 96
- 2022Medical Image Understanding with Pretrained Vision Language Models: A Comprehensive Studycited by 66
- 2024TotalSegmentator MRI: Robust Sequence-independent Segmentation of Multiple Anatomic Structures in MRIcited by 59
- 2023SA-Med2D-20M Dataset: Segment Anything in 2D Medical Imaging with 20 Million maskscited by 55
- 2024PathMMU: A Massive Multimodal Expert-Level Benchmark for Understanding and Reasoning in Pathologycited by 43
- 2024CXPMRG-Bench: Pre-training and Benchmarking for X-ray Medical Report Generation on CheXpert Plus Datasetcited by 35
- 2025Position: Multimodal Large Language Models Can Significantly Advance Scientific Reasoningcited by 33
- 2024MultiMedEval: A Benchmark and a Toolkit for Evaluating Medical Vision-Language Modelscited by 29
- 2023GraphEcho: Graph-Driven Unsupervised Domain Adaptation for Echocardiogram Video Segmentationcited by 22
- 2017MURA: Large Dataset for Abnormality Detection in Musculoskeletal Radiographscited by 20
- 2024A Survey of Medical Vision-and-Language Applications and Their Techniquescited by 11
- 2022RESECT-SEG: Open access annotations of intra-operative brain tumor ultrasound imagescited by 6
- 2024Improving Medical Diagnostics with Vision-Language Models: Convex Hull-Based Uncertainty Analysiscited by 3
Built on by
Citing papers per year: 2025: 3; 2026: 7.
10 papers.
- 2026BabyVision: Visual Reasoning Beyond Languagecited by 49
- 20256 Fingers, 1 Kidney: Natural Adversarial Medical Images Reveal Critical Weaknesses of Vision-Language Modelscited by 3
- 2026Unveiling and Bridging the Functional Perception Gap in MLLMs: Atomic Visual Alignment and Hierarchical Evaluation via PET-Benchcited by 3
- 2026NeuroVLM-Bench: Evaluation of Vision-Enabled Large Language Models for Clinical Reasoning in Neurological Disorderscited by 1
- 2026CORTEX: A Structured Reasoning Benchmark for Trustworthy 3D Chest CT MLLMscited by 1
- 2025MedGEN-Bench: A Contextually Entangled Benchmark for Open-ended Multimodal Medical Generationcited by 0
- 2025MedVision: Benchmarking Quantitative Medical Image Analysiscited by 0
- 2026Med-R2: An Adversarial Benchmark for Evidence-Grounded Reasoning in Medical VLMscited by 0
- 2026How Good are Foundation Models in Longitudinal MRI Disease Progression Reasoning?cited by 0
- 2026DementiaCare-Bench: A Modality-Validated Video Benchmarkcited by 0
- 2026DementiaCare-Bench: A Modality-Validated Video Benchmark11 Sep 2026
- 2026How Good are Foundation Models in Longitudinal MRI Disease Progression Reasoning?13 Aug 2026
- 2026CORTEX: A Structured Reasoning Benchmark for Trustworthy 3D Chest CT MLLMs25 Jun 2026
- 2026Med-R2: An Adversarial Benchmark for Evidence-Grounded Reasoning in Medical VLMs23 May 2026
- 2026NeuroVLM-Bench: Evaluation of Vision-Enabled Large Language Models for Clinical Reasoning in Neurological Disorders25 Mar 2026
- 2026BabyVision: Visual Reasoning Beyond Language10 Jan 2026
- 2026Unveiling and Bridging the Functional Perception Gap in MLLMs: Atomic Visual Alignment and Hierarchical Evaluation via PET-Bench6 Jan 2026
- 20256 Fingers, 1 Kidney: Natural Adversarial Medical Images Reveal Critical Weaknesses of Vision-Language Models3 Dec 2025
- 2025MedVision: Benchmarking Quantitative Medical Image Analysis24 Nov 2025
- 2025MedGEN-Bench: A Contextually Entangled Benchmark for Open-ended Multimodal Medical Generation17 Nov 2025
Similar, not cited
Close in wording, no citation either way
- 2025How Far Have Medical Vision-Language Models Come? A Comprehensive Benchmarking Study
- 2025TemMed-Bench: Evaluating Temporal Medical Image Reasoning in Vision-Language Models
- 2025MedVLM-R1: Incentivizing Medical Reasoning Capability of Vision-Language Models (VLMs) via Reinforcement Learning
- 2026PathLang: A Language-Centered Benchmark for Vision-Language Models in Computational Pathology
- 2025Beyond Classification Accuracy: Neural-MedBench and the Need for Deeper Reasoning Benchmarks
- 2025Think Twice to See More: Iterative Visual Reasoning in Medical VLMs
- 2025The Illusion of Clinical Reasoning: A Benchmark Reveals the Pervasive Gap in Vision-Language Models for Clinical Competency
- 2026How Do Medical MLLMs Fail? A Study on Visual Grounding in Medical Images