Talk Before You Retrieve: Agent-Led Discussions for Better RAG in Medical QA
On the map: Retrieval-augmented generation → Medical and biomedical RAG
also in 1 more
Abstract (arXiv)
Medical question answering (QA) is a reasoning-intensive task that remains challenging for large language models (LLMs) due to hallucinations and outdated domain knowledge. Retrieval-Augmented Generation (RAG) provides a promising post-training solution by leveraging external knowledge. However, existing medical RAG systems suffer from two key limitations: (1) a lack of modeling for human-like reasoning behaviors during information retrieval, and (2) reliance on suboptimal medical corpora, which often results in the retrieval of irrelevant or noisy snippets. To overcome these challenges, we propose Discuss-RAG, a plug-and-play module designed to enhance the medical QA RAG system through collaborative agent-based reasoning. Our method introduces a summarizer agent that orchestrates a team of medical experts to emulate multi-turn brainstorming, thereby improving the relevance of retrieved content. Additionally, a decision-making agent evaluates the retrieved snippets before their final integration. Experimental results on four benchmark medical QA datasets show that Discuss-RAG consistently outperforms MedRAG, especially significantly improving answer accuracy by up to 16.67% on BioASQ and 12.20% on PubMedQA. The code is available at: https://github.com/LLM-VLM-GSL/Discuss-RAG.
Key facts. Cited by 6 papers in the map (data through 14 Oct 2026). Placed in Medical and biomedical RAG, one of 15 directions in Retrieval-augmented generation. Builds on 10 of its 18 references that are in the map. First posted on arXiv 30 Apr 2025.
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10 of 18 references.
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Other references · 9
- 2020Measuring Massive Multitask Language Understandingcited by 7,963
- 2020REALM: Retrieval-Augmented Language Model Pre-Trainingcited by 2,141
- 2022Large Language Models Encode Clinical Knowledgecited by 1,830
- 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,356
- 2019PubMedQA: A Dataset for Biomedical Research Question Answeringcited by 1,288
- 2020Leveraging Passage Retrieval with Generative Models for Open Domain Question Answeringcited by 1,210
- 2023Capabilities of GPT-4 on Medical Challenge Problemscited by 638
- 2023MedCPT: Contrastive Pre-trained Transformers with Large-scale PubMed Search Logs for Zero-shot Biomedical Information Retrievalcited by 185
- 2024Seven Failure Points When Engineering a Retrieval Augmented Generation Systemcited by 139
Built on by
Citing papers per year: 2025: 2; 2026: 4.
6 papers.
- 2026EZBlender: Efficient 3D Editing with Plan-and-ReAct Agentcited by 4
- 2025Empowering Real-World: A Survey on the Technology, Practice, and Evaluation of LLM-driven Industry Agentscited by 2
- 2025Contradictions in Context: Challenges for Retrieval-Augmented Generation in Healthcarecited by 1
- 2026OphIn-500K: Curating Web-Scale Visual Instructions for Scaling Ophthalmic Multimodal Large Language Modelscited by 1
- 2026Self-MedRAG: a Self-Reflective Hybrid Retrieval-Augmented Generation Framework for Reliable Medical Question Answeringcited by 0
- 2026When Cases Get Rare: A Retrieval Benchmark for Off-Guideline Clinical Question Answeringcited by 0
- 2026OphIn-500K: Curating Web-Scale Visual Instructions for Scaling Ophthalmic Multimodal Large Language Models27 May 2026
- 2026When Cases Get Rare: A Retrieval Benchmark for Off-Guideline Clinical Question Answering20 May 2026
- 2026EZBlender: Efficient 3D Editing with Plan-and-ReAct Agent12 Jan 2026
- 2026Self-MedRAG: a Self-Reflective Hybrid Retrieval-Augmented Generation Framework for Reliable Medical Question Answering8 Jan 2026
- 2025Contradictions in Context: Challenges for Retrieval-Augmented Generation in Healthcare10 Nov 2025
- 2025Empowering Real-World: A Survey on the Technology, Practice, and Evaluation of LLM-driven Industry Agents20 Oct 2025
Similar, not cited
Close in wording, no citation either way
- 2024Comprehensive and Practical Evaluation of Retrieval-Augmented Generation Systems for Medical Question Answering
- 2026RAG-X: Systematic Diagnosis of Retrieval-Augmented Generation for Medical Question Answering
- 2026SEMA-RAG: A Self-Evolving Multi-Agent Retrieval-Augmented Generation Framework for Medical Reasoning
- 2026From Conflict to Consensus: Boosting Medical Reasoning via Multi-Round Agentic RAG
- 2025Agentic Medical Knowledge Graphs Enhance Medical Question Answering: Bridging the Gap Between LLMs and Evolving Medical Knowledge
- 2026When Retrieval Doesn't Help: A Large-Scale Study of Biomedical RAG
- 2026A Systematic Study of Retrieval Pipeline Design for Retrieval-Augmented Medical Question Answering
- 2024Rationale-Guided Retrieval Augmented Generation for Medical Question Answering