FunBench: Benchmarking Fundus Reading Skills of MLLMs
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
Abstract (arXiv)
Multimodal Large Language Models (MLLMs) have shown significant potential in medical image analysis. However, their capabilities in interpreting fundus images, a critical skill for ophthalmology, remain under-evaluated. Existing benchmarks lack fine-grained task divisions and fail to provide modular analysis of its two key modules, i.e., large language model (LLM) and vision encoder (VE). This paper introduces FunBench, a novel visual question answering (VQA) benchmark designed to comprehensively evaluate MLLMs' fundus reading skills. FunBench features a hierarchical task organization across four levels (modality perception, anatomy perception, lesion analysis, and disease diagnosis). It also offers three targeted evaluation modes: linear-probe based VE evaluation, knowledge-prompted LLM evaluation, and holistic evaluation. Experiments on nine open-source MLLMs plus GPT-4o reveal significant deficiencies in fundus reading skills, particularly in basic tasks such as laterality recognition. The results highlight the limitations of current MLLMs and emphasize the need for domain-specific training and improved LLMs and VEs.
Key facts. Cited by 5 papers in the map (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 23 of its 36 references that are in the map. First posted on arXiv 2 Mar 2025.
Builds on
23 of 36 references.
Closest ancestors · 6
Same direction, newest first
- 2024LMOD: A Large Multimodal Ophthalmology Dataset and Benchmark for Large Vision-Language Models2 Oct
- 2024GMAI-MMBench: A Comprehensive Multimodal Evaluation Benchmark Towards General Medical AI6 Aug
- 2024HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scale27 Jun
- 2024OmniMedVQA: A New Large-Scale Comprehensive Evaluation Benchmark for Medical LVLM14 Feb
- 2023Qilin-Med-VL: Towards Chinese Large Vision-Language Model for General Healthcare27 Oct
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day1 Jun
Other references · 17
- 2019Sentence-BERT: Sentence Embeddings using Siamese BERT-Networkscited by 9,049
- 2023DINOv2: Learning Robust Visual Features without Supervisioncited by 7,764
- 2024GPT-4o System Cardcited by 4,467
- 2023Improved Baselines with Visual Instruction Tuningcited by 4,362
- 2024Qwen2-VL: Enhancing Vision-Language Model's Perception of the World at Any Resolutioncited by 4,151
- 2024Expanding Performance Boundaries of Open-Source Multimodal Models with Model, Data, and Test-Time Scalingcited by 1,573
- 2025Janus-Pro: Unified Multimodal Understanding and Generation with Data and Model Scalingcited by 787
- 2022Visual Query Tuning: Towards Effective Usage of Intermediate Representations for Parameter and Memory Efficient Transfer Learningcited by 57
- 2018OCTID: Optical Coherence Tomography Image Databasecited by 36
- 2021A Benchmark of Ocular Disease Intelligent Recognition: One Shot for Multi-disease Detectioncited by 34
- 2019Learn to Segment Retinal Lesions and Beyondcited by 33
- 2023OCTDL: Optical Coherence Tomography Dataset for Image-Based Deep Learning Methodscited by 28
5 more
- 2024PitVQA: Image-grounded Text Embedding LLM for Visual Question Answering in Pituitary Surgerycited by 22
- 2020Learning Two-Stream CNN for Multi-Modal Age-related Macular Degeneration Categorizationcited by 15
- 2021Multi-Scale Convolutional Neural Network for Automated AMD Classification using Retinal OCT Imagescited by 10
- 2024Insight: A Multi-Modal Diagnostic Pipeline using LLMs for Ocular Surface Disease Diagnosiscited by 6
- 2024Incorporating Clinical Guidelines through Adapting Multi-modal Large Language Model for Prostate Cancer PI-RADS Scoringcited by 2
Built on by
Citing papers per year: 2025: 2; 2026: 3.
5 papers.
- 2025EH-Benchmark Ophthalmic Hallucination Benchmark and Agent-Driven Top-Down Traceable Reasoning Workflowcited by 2
- 2025Benchmarking Large Multimodal Models for Ophthalmic Visual Question Answering with OphthalWeChatcited by 1
- 2026Towards Clinically Interpretable Ophthalmic VQA via Spatially-Grounded Lesion Evidencecited by 1
- 2026From Pixels to Explanations: Interpretable Diabetic Retinopathy Grading with CNN-Transformer Ensembles, Visual Explainability and Vision-Language Modelscited by 0
- 2026FOCUS: Benchmarking Retinal Model Generalization from Foundation Vision Encoders to Multimodal LLMscited by 0
- 2026FOCUS: Benchmarking Retinal Model Generalization from Foundation Vision Encoders to Multimodal LLMs27 Sep 2026
- 2026Towards Clinically Interpretable Ophthalmic VQA via Spatially-Grounded Lesion Evidence21 May 2026
- 2026From Pixels to Explanations: Interpretable Diabetic Retinopathy Grading with CNN-Transformer Ensembles, Visual Explainability and Vision-Language Models25 Apr 2026
- 2025EH-Benchmark Ophthalmic Hallucination Benchmark and Agent-Driven Top-Down Traceable Reasoning Workflow24 Jul 2025
- 2025Benchmarking Large Multimodal Models for Ophthalmic Visual Question Answering with OphthalWeChat26 May 2025
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- 2025A Novel Ophthalmic Benchmark for Evaluating Multimodal Large Language Models with Fundus Photographs and OCT Images
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