Retrieval-augmented systems can be dangerous medical communicators
On the map: Retrieval-augmented generation → Medical and biomedical RAG
Abstract (arXiv)
Patients have long sought health information online, and increasingly, they are turning to generative AI to answer their health-related queries. Given the high stakes of the medical domain, techniques like retrieval-augmented generation and citation grounding have been widely promoted as methods to reduce hallucinations and improve the accuracy of AI-generated responses and have been widely adopted into search engines. This paper argues that even when these methods produce literally accurate content drawn from source documents sans hallucinations, they can still be highly misleading. Patients may derive significantly different interpretations from AI-generated outputs than they would from reading the original source material, let alone consulting a knowledgeable clinician. Through a large-scale query analysis on topics including disputed diagnoses and procedure safety, we support our argument with quantitative and qualitative evidence of the suboptimal answers resulting from current systems. In particular, we highlight how these models tend to decontextualize facts, omit critical relevant sources, and reinforce patient misconceptions or biases. We propose a series of recommendations -- such as the incorporation of communication pragmatics and enhanced comprehension of source documents -- that could help mitigate these issues and extend beyond the medical domain.
Key facts. Cited by 5 papers in the map (data through 7 Oct 2026). Placed in Medical and biomedical RAG, one of 15 directions in Retrieval-augmented generation. Builds on 15 of its 41 references that are in the map. First posted on arXiv 18 Feb 2025.
Builds on
15 of 41 references.
References · 15
- 2021Retrieval Augmentation Reduces Hallucination in Conversationcited by 691
- 2024WildChat: 1M ChatGPT Interaction Logs in the Wildcited by 598
- 2023ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledgecited by 324
- 2024Building Machines that Learn and Think with Peoplecited by 73
- 2024OpenScholar: Synthesizing Scientific Literature with Retrieval-augmented LMscited by 64
- 2023When Large Language Models contradict humans? Large Language Models' Sycophantic Behaviourcited by 61
- 2023Grounding Gaps in Language Model Generationscited by 45
- 2024Pragmatic Instruction Following and Goal Assistance via Cooperative Language-Guided Inverse Planningcited by 28
- 2024Search Engines in an AI Era: The False Promise of Factual and Verifiable Source-Cited Responsescited by 15
- 2024Argumentative Experience: Reducing Confirmation Bias on Controversial Issues through LLM-Generated Multi-Persona Debatescited by 15
- 2024Human-like Affective Cognition in Foundation Modelscited by 13
- 2023The Usability of Pragmatic Communication in Regular Expression Synthesiscited by 4
Built on by
Citing papers per year: 2025: 2; 2026: 3.
5 papers.
- 2025Forecasting Clinical Risk from Textual Time Series: Structuring Narratives for Temporal AI in Healthcarecited by 5
- 2025Revealing the Numeracy Gap: An Empirical Investigation of Text Embedding Modelscited by 1
- 2026Deceptive Grounding: Entity Attribution Failure in Clinical Retrieval-Augmented Generationcited by 0
- 2026An Investigation of the NeurIPS and ICML 2025 Position Trackscited by 0
- 2026CLEAR: Cross-Source Evidence Adjudication for Large Language Models in Medicinecited by 0
- 2026CLEAR: Cross-Source Evidence Adjudication for Large Language Models in Medicine14 Sep 2026
- 2026Deceptive Grounding: Entity Attribution Failure in Clinical Retrieval-Augmented Generation10 Jul 2026
- 2026An Investigation of the NeurIPS and ICML 2025 Position Tracks6 Jul 2026
- 2025Revealing the Numeracy Gap: An Empirical Investigation of Text Embedding Models6 Sep 2025
- 2025Forecasting Clinical Risk from Textual Time Series: Structuring Narratives for Temporal AI in Healthcare14 Apr 2025
Similar, not cited
Close in wording, no citation either way
- 2025Contradictions in Context: Challenges for Retrieval-Augmented Generation in Healthcare
- 2025Evaluating the Robustness of Retrieval-Augmented Generation to Adversarial Evidence in the Health Domain
- 2025Rethinking Retrieval-Augmented Generation for Medicine: A Large-Scale, Systematic Expert Evaluation and Practical Insights
- 2025Enhancing Health Information Retrieval with RAG by Prioritizing Topical Relevance and Factual Accuracy
- 2026When Retrieval Doesn't Help: A Large-Scale Study of Biomedical RAG
- 2026Evaluating Factual Density in Multi-Source RAG: A Study in Medical AI Accuracy
- 2025Multi-Agent Retrieval-Augmented Framework for Evidence-Based Counterspeech Against Health Misinformation
- 2024Towards Reliable Medical Question Answering: Techniques and Challenges in Mitigating Hallucinations in Language Models