mlsanityData to 14 Oct 2026

Evaluating the Robustness of Retrieval-Augmented Generation to Adversarial Evidence in the Health Domain

arXiv 2509.03787 ↗First posted 4 Sep 2025cs.IR cs.CLcited by 6

On the map: Retrieval-augmented generation → Medical and biomedical RAG

Abstract (arXiv)

Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce hallucinations and expand the ability of LLMs to accurately answer questions outside the scope of their training data. Unfortunately, this design introduces a critical vulnerability: LLMs may absorb and reproduce misinformation present in retrieved evidence. This problem is magnified if retrieved evidence contains adversarial material explicitly intended to promulgate misinformation. This paper presents a systematic evaluation of RAG robustness in the health domain and examines alignment between model outputs and ground-truth answers. We focus on the health domain due to the potential for harm caused by incorrect responses, as well as the availability of evidence-based ground truth for many common health-related questions. We conduct controlled experiments using common health questions, varying both the type and composition of the retrieved documents (helpful, harmful, and adversarial) as well as the framing of the question by the user (consistent, neutral, and inconsistent). Our findings reveal that adversarial documents substantially degrade alignment, but robustness can be preserved when helpful evidence is also present in the retrieval pool. These findings offer actionable insights for designing safer RAG systems in high-stakes domains by highlighting the need for retrieval safeguards. To enable reproducibility and facilitate future research, all experimental results are publicly available in our github repository. https://github.com/shakibaam/RAG_ROBUSTNESS_EVAL

Key facts. Cited by 6 papers in the map (data through 14 Oct 2026). Placed in Medical and biomedical RAG, one of 15 directions in Retrieval-augmented generation. Builds on 65 of its 80 references that are in the map. First posted on arXiv 4 Sep 2025.

Builds on

65 of 80 references.

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  1. 2024Benchmarking Retrieval-Augmented Generation for Medicine20 Feb

Other references · 64

  1. 2024The Llama 3 Herd of Modelscited by 14,715
  2. 2020Retrieval-Augmented Generation for Knowledge-Intensive NLP Taskscited by 9,297
  3. 2019BART: Denoising Sequence-to-Sequence Pre-training for Natural Language Generation, Translation, and Comprehensioncited by 5,893
  4. 2023Lost in the Middle: How Language Models Use Long Contextscited by 3,455
  5. 2023Universal and Transferable Adversarial Attacks on Aligned Language Modelscited by 3,104
  6. 2023Retrieval-Augmented Generation for Large Language Models: A Surveycited by 2,212
  7. 2023Jailbroken: How Does LLM Safety Training Fail?cited by 1,651
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  9. 2023Not what you've signed up for: Compromising Real-World LLM-Integrated Applications with Indirect Prompt Injectioncited by 1,443
  10. 2023Jailbreaking Black Box Large Language Models in Twenty Queriescited by 1,420
  11. 2020Leveraging Passage Retrieval with Generative Models for Open Domain Question Answeringcited by 1,210
  12. 2022Atlas: Few-shot Learning with Retrieval Augmented Language Modelscited by 952
38 more
  1. 2023ChatGPT Outperforms Crowd-Workers for Text-Annotation Taskscited by 870
  2. 2023Can Large Language Models Be an Alternative to Human Evaluations?cited by 734
  3. 2023Baseline Defenses for Adversarial Attacks Against Aligned Language Modelscited by 651
  4. 2023SmoothLLM: Defending Large Language Models Against Jailbreaking Attackscited by 469
  5. 2020Document Ranking with a Pretrained Sequence-to-Sequence Modelcited by 376
  6. 2023Multi-step Jailbreaking Privacy Attacks on ChatGPTcited by 333
  7. 2023How Language Model Hallucinations Can Snowballcited by 311
  8. 2023State of What Art? A Call for Multi-Prompt LLM Evaluationcited by 310
  9. 2020Overview of the TREC 2019 deep learning trackcited by 286
  10. 2024The Power of Noise: Redefining Retrieval for RAG Systemscited by 281
  11. 2024PoisonedRAG: Knowledge Corruption Attacks to Retrieval-Augmented Generation of Large Language Modelscited by 267
  12. 2023Certifying LLM Safety against Adversarial Promptingcited by 266
  13. 2023LLM Self Defense: By Self Examination, LLMs Know They Are Being Trickedcited by 244
  14. 2024SecAlign: Defending Against Prompt Injection with Preference Optimizationcited by 210
  15. 2021Overview of the TREC 2020 deep learning trackcited by 196
  16. 2025Constitutional Classifiers: Defending against Universal Jailbreaks across Thousands of Hours of Red Teamingcited by 181
  17. 2022DocPrompting: Generating Code by Retrieving the Docscited by 153
  18. 2024AutoDefense: Multi-Agent LLM Defense against Jailbreak Attackscited by 145
  19. 2024Optimization-based Prompt Injection Attack to LLM-as-a-Judgecited by 143
  20. 2022Improving the Domain Adaptation of Retrieval Augmented Generation (RAG) Models for Open Domain Question Answeringcited by 127
  21. 2025PromptArmor: Simple yet Effective Prompt Injection Defensescited by 108
  22. 2023Jatmo: Prompt Injection Defense by Task-Specific Finetuningcited by 106
  23. 2024Defending Against Unforeseen Failure Modes with Latent Adversarial Trainingcited by 88
  24. 2024RigorLLM: Resilient Guardrails for Large Language Models against Undesired Contentcited by 68
  25. 2024Typos that Broke the RAG's Back: Genetic Attack on RAG Pipeline by Simulating Documents in the Wild via Low-level Perturbationscited by 65
  26. 2023A Multi-Task Embedder For Retrieval Augmented LLMscited by 64
  27. 2022Entity Cloze By Date: What LMs Know About Unseen Entitiescited by 55
  28. 2023From Prompt Injections to SQL Injection Attacks: How Protected is Your LLM-Integrated Web Application?cited by 55
  29. 2025JBShield: Defending Large Language Models from Jailbreak Attacks through Activated Concept Analysis and Manipulationcited by 54
  30. 2025PromptShield: Deployable Detection for Prompt Injection Attackscited by 50
  31. 2024Phantom: General Backdoor Attacks on Retrieval Augmented Language Generationcited by 49
  32. 2022PRADA: Practical Black-Box Adversarial Attacks against Neural Ranking Modelscited by 44
  33. 2023LeanContext: Cost-Efficient Domain-Specific Question Answering Using LLMscited by 40
  34. 2022Order-Disorder: Imitation Adversarial Attacks for Black-box Neural Ranking Modelscited by 37
  35. 2024Ragnar"ok: A Reusable RAG Framework and Baselines for TREC 2024 Retrieval-Augmented Generation Trackcited by 32
  36. 2025Poison-RAG: Adversarial Data Poisoning Attacks on Retrieval-Augmented Generation in Recommender Systemscited by 32
  37. 2023Black-box Adversarial Attacks against Dense Retrieval Models: A Multi-view Contrastive Learning Methodcited by 29
  38. 2024Embedding-based classifiers can detect prompt injection attackscited by 27

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Cited by year (2026 to 14 Oct)

Citing papers per year: 2026: 6.

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  1. 2024Enhancing Large Language Models with Domain-specific Retrieval Augment Generation: A Case Study on Long-form Consumer Health Question Answering in Ophthalmology
  2. 2024Towards More Robust Retrieval-Augmented Generation: Evaluating RAG Under Adversarial Poisoning Attacks
  3. 2024Adversarial Databases Improve Success in Retrieval-based Large Language Models
  4. 2024LLM Robustness Against Misinformation in Biomedical Question Answering
  5. 2026Healthier LLMs: Retrieval-Augmented Generation for Public Health Question Answering
  6. 2024On the Vulnerability of Applying Retrieval-Augmented Generation within Knowledge-Intensive Application Domains
  7. 2025Retrieval-Augmented Generation: A Comprehensive Survey of Architectures, Enhancements, and Robustness Frontiers
  8. 2025Contradictions in Context: Challenges for Retrieval-Augmented Generation in Healthcare