Memorize and Rank: Elevating Large Language Models for Clinical Diagnosis Prediction
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Abstract (arXiv)
Clinical diagnosis prediction models, when provided with a patient's medical history, aim to detect potential diseases early, facilitating timely intervention and improving prognostic outcomes. However, the inherent scarcity of patient data and large disease candidate space often pose challenges in developing satisfactory models for this intricate task. The exploration of leveraging Large Language Models (LLMs) for encapsulating clinical decision processes has been limited. We introduce MERA, a clinical diagnosis prediction model that bridges pertaining natural language knowledge with medical practice. We apply hierarchical contrastive learning on a disease candidate ranking list to alleviate the large decision space issue. With concept memorization through fine-tuning, we bridge the natural language clinical knowledge with medical codes. Experimental results on MIMIC-III and IV datasets show that MERA achieves the state-of-the-art diagnosis prediction performance and dramatically elevates the diagnosis prediction capabilities of generative LMs.
Key facts. Cited by 8 papers in the map (data through 14 Oct 2026). Builds on 34 of its 60 references that are in the map. First posted on arXiv 28 Jan 2025.
Builds on
34 of 60 references.
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Citing papers per year: 2025: 4; 2026: 4.
8 papers.
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- 2026The Taxonomies, Training, and Applications of Event Stream Modelling for Electronic Health Records14 Mar 2026
- 2026MIND: Unified Inquiry and Diagnosis RL with Criteria Grounded Clinical Supports for Psychiatric Consultation4 Mar 2026
- 2025Stable Prediction of Adverse Events in Medical Time-Series Data16 Oct 2025
- 2025DDO: Dual-Decision Optimization for LLM-Based Medical Consultation via Multi-Agent Collaboration24 May 2025
- 2025RuCCoD: Towards Automated ICD Coding in Russian28 Feb 2025
- 2025Large Language Models are Powerful Electronic Health Record Encoders24 Feb 2025