Improved Generation of Synthetic Imaging Data Using Feature-Aligned Diffusion
On the map: Diffusion models → Medical imaging and segmentation
Abstract (arXiv)
Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential improvements to this pipeline through feature-aligned diffusion. Our approach aligns intermediate features of the diffusion model to the output features of an expert, and our preliminary findings show an improvement of 9% in generation accuracy and ~0.12 in SSIM diversity. Our approach is also synergistic with existing methods, and easily integrated into diffusion training pipelines for improvements. We make our code available at urlhttps://github.com/lnairGT/Feature-Aligned-Diffusion.
Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 10 of its 17 references that are in the map. First posted on arXiv 1 Oct 2024.
Builds on
10 of 17 references.
Closest ancestors · 4
Same direction, newest first
- 2024Understanding Hallucinations in Diffusion Models through Mode Interpolation13 Jun
- 2024Derm-T2IM: Harnessing Synthetic Skin Lesion Data via Stable Diffusion Models for Enhanced Skin Disease Classification using ViT and CNN10 Jan
- 2023MAM-E: Mammographic synthetic image generation with diffusion models16 Nov
- 2022Diffusion Models for Medical Image Analysis: A Comprehensive Survey14 Nov
Other references · 6
- 2015Deep Residual Learning for Image Recognitioncited by 52,096
- 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 30,186
- 2020Denoising Diffusion Probabilistic Modelscited by 21,076
- 2021High-Resolution Image Synthesis with Latent Diffusion Modelscited by 18,863
- 2022DreamBooth: Fine Tuning Text-to-Image Diffusion Models for Subject-Driven Generationcited by 3,300
- 2024Aligning Diffusion Models with Noise-Conditioned Perceptioncited by 9
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Citing papers per year: 2025: 1.
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- 2025Computationally Efficient Diffusion Models in Medical Imaging: A Comprehensive Review
- 2023Beware of diffusion models for synthesizing medical images -- A comparison with GANs in terms of memorizing brain MRI and chest x-ray images
- 2022Evaluating a Synthetic Image Dataset Generated with Stable Diffusion
- 2024DiNO-Diffusion. Scaling Medical Diffusion via Self-Supervised Pre-Training