mlsanityData to 7 Oct 2026

Virtual Agents for Alcohol Use Counseling: Exploring LLM-Powered Motivational Interviewing

arXiv 2407.08095 ↗First posted 10 Jul 2024cs.HC cs.CLcited by 17

On the map: LLM agents and tool use → Medical and scientific domain agents

Abstract (arXiv)

We introduce a novel application of large language models (LLMs) in developing a virtual counselor capable of conducting motivational interviewing (MI) for alcohol use counseling. Access to effective counseling remains limited, particularly for substance abuse, and virtual agents offer a promising solution by leveraging LLM capabilities to simulate nuanced communication techniques inherent in MI. Our approach combines prompt engineering and integration into a user-friendly virtual platform to facilitate realistic, empathetic interactions. We evaluate the effectiveness of our virtual agent through a series of studies focusing on replicating MI techniques and human counselor dialog. Initial findings suggest that our LLM-powered virtual agent matches human counselors' empathetic and adaptive conversational skills, presenting a significant step forward in virtual health counseling and providing insights into the design and implementation of LLM-based therapeutic interactions.

Key facts. Cited by 17 papers in the map (data through 7 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 5 of its 54 references that are in the map. First posted on arXiv 10 Jul 2024.

Builds on

5 of 54 references.

References · 5

  1. 2022Training a Helpful and Harmless Assistant with Reinforcement Learning from Human Feedbackcited by 3,634
  2. 2023Large Language Models Understand and Can be Enhanced by Emotional Stimulicited by 143
  3. 2024Large Language Models Produce Responses Perceived to be Empathiccited by 36
  4. 2024Polaris: A Safety-focused LLM Constellation Architecture for Healthcarecited by 27
  5. 2024Gemini Goes to Med School: Exploring the Capabilities of Multimodal Large Language Models on Medical Challenge Problems & Hallucinationscited by 26

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2025: 12; 2026: 5.

17 papers.

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  1. 2025Scaffolding Empathy: Training Counselors with Simulated Patients and Utterance-level Performance Visualizationscited by 14
  2. 2025Mitigating Response Delays in Free-Form Conversations with LLM-powered Intelligent Virtual Agentscited by 12
  3. 2025CAMI: A Counselor Agent Supporting Motivational Interviewing through State Inference and Topic Explorationcited by 11
  4. 2025Substance over Style: Evaluating Proactive Conversational Coaching Agentscited by 6
  5. 2025A Risk Ontology for Evaluating AI-Powered Psychotherapy Virtual Agentscited by 5
  6. 2025A Fully Generative Motivational Interviewing Counsellor Chatbot for Moving Smokers Towards the Decision to Quitcited by 5
  7. 2025Can LLMs Generate Behaviors for Embodied Virtual Agents Based on Personality Traits?cited by 5
  8. 2025Emotions, Context, and Substance Use in Adolescents: A Large Language Model Analysis of Reddit Postscited by 2
  9. 2025Tailored Conversations beyond LLMs: A RL-Based Dialogue Managercited by 1
  10. 2025HealthDial: A No-Code LLM-Assisted Dialogue Authoring Tool for Healthcare Virtual Agentscited by 1
  11. 2025When LLM Therapists Become Salespeople: Evaluating Large Language Models for Ethical Motivational Interviewingcited by 0
  12. 2025Controlled Yet Natural: A Hybrid BDI-LLM Conversational Agent for Child Helpline Trainingcited by 0
5 more
  1. 2026Initial Risk Probing and Feasibility Testing of Glow: a Generative AI-Powered Dialectical Behavior Therapy Skills Coach for Substance Use Recovery and HIV Preventioncited by 0
  2. 2026Benchmarking Motivational Interviewing Competence of Large Language Modelscited by 0
  3. 2026COACH meets QUORUM: A Framework and Pipeline for Aligning User, Expert and Developer Perspectives in LLM-generated Health Counsellingcited by 0
  4. 2026StoryMI: Steerable Multi-Agent Therapeutic Dialogue Generationcited by 0
  5. 2026MIThinker: A Plug-and-Play Policy-Optimized Thinker For Motivational Interviewing Counselingcited by 0

Similar, not cited

Close in wording, no citation either way

  1. 2025AI-Augmented LLMs Achieve Therapist-Level Responses in Motivational Interviewing
  2. 2024Interactive Agents: Simulating Counselor-Client Psychological Counseling via Role-Playing LLM-to-LLM Interactions
  3. 2026Can Virtual Agents Care? Designing an Empathetic and Personalized LLM-Driven Conversational Agent
  4. 2025Large Language Model-Powered Conversational Agent Delivering Problem-Solving Therapy (PST) for Family Caregivers: Enhancing Empathy and Therapeutic Alliance Using In-Context Learning
  5. 2025TheraMind: A Strategic and Adaptive Agent for Longitudinal Psychological Counseling
  6. 2025Psi-Arena: Interactive Assessment and Optimization of LLM-based Psychological Counselors with Tripartite Feedback
  7. 2026XInsight: Integrative Stage-Consistent Psychological Counseling Support Agents for Digital Well-Being
  8. 2024An LLM-based Simulation Framework for Embodied Conversational Agents in Psychological Counseling