mlsanityData to 14 Oct 2026

Large Language Model-Powered Conversational Agent Delivering Problem-Solving Therapy (PST) for Family Caregivers: Enhancing Empathy and Therapeutic Alliance Using In-Context Learning

arXiv 2506.11376 ↗First posted 13 Jun 2025cs.AI cs.CL cs.HCcited by 1

On the map: LLM agents and tool use → Medical and scientific domain agents

Abstract (arXiv)

Family caregivers often face substantial mental health challenges due to their multifaceted roles and limited resources. This study explored the potential of a large language model (LLM)-powered conversational agent to deliver evidence-based mental health support for caregivers, specifically Problem-Solving Therapy (PST) integrated with Motivational Interviewing (MI) and Behavioral Chain Analysis (BCA). A within-subject experiment was conducted with 28 caregivers interacting with four LLM configurations to evaluate empathy and therapeutic alliance. The best-performing models incorporated Few-Shot and Retrieval-Augmented Generation (RAG) prompting techniques, alongside clinician-curated examples. The models showed improved contextual understanding and personalized support, as reflected by qualitative responses and quantitative ratings on perceived empathy and therapeutic alliances. Participants valued the model's ability to validate emotions, explore unexpressed feelings, and provide actionable strategies. However, balancing thorough assessment with efficient advice delivery remains a challenge. This work highlights the potential of LLMs in delivering empathetic and tailored support for family caregivers.

Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 7 of its 45 references that are in the map. First posted on arXiv 13 Jun 2025.

Builds on

7 of 45 references.

References · 7

  1. 2021Retrieval Augmentation Reduces Hallucination in Conversationcited by 692
  2. 2021Towards Emotional Support Dialog Systemscited by 299
  3. 2020A Computational Approach to Understanding Empathy Expressed in Text-Based Mental Health Supportcited by 182
  4. 2024Are Large Language Models More Empathetic than Humans?cited by 18
  5. 2021An Evaluation of Generative Pre-Training Model-based Therapy Chatbot for Caregiverscited by 15
  6. 2024Development of a Reliable and Accessible Caregiving Language Model (CaLM)cited by 5
  7. 2024Toward Large Language Models as a Therapeutic Tool: Comparing Prompting Techniques to Improve GPT-Delivered Problem-Solving Therapycited by 5

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Cited by year (2026 to 14 Oct)

Citing papers per year: 2026: 1.

1 paper.

Similar, not cited

Close in wording, no citation either way

  1. 2025Beyond Empathy: Integrating Diagnostic and Therapeutic Reasoning with Large Language Models for Mental Health Counseling
  2. 2025Adaptive LLM Agents: Toward Personalized Empathetic Care
  3. 2026Can Virtual Agents Care? Designing an Empathetic and Personalized LLM-Driven Conversational Agent
  4. 2026Assessing the Effectiveness of LLMs in Delivering Cognitive Behavioral Therapy
  5. 2026Mind Companion: An Embodied Conversational Agent for Process-Based Psychotherapy
  6. 2023Understanding the Benefits and Challenges of Using Large Language Model-based Conversational Agents for Mental Well-being Support
  7. 2026CARE: Counselor-Aligned Response Engine for Online Mental-Health Support
  8. 2024Large Language Model Agents for Improving Engagement with Behavior Change Interventions: Application to Digital Mindfulness