Synth-SBDH: A Synthetic Dataset of Social and Behavioral Determinants of Health for Clinical Text
On the map: Synthetic data and self-improvement for LLMs → Medical synthetic data and agents
Abstract (arXiv)
Social and behavioral determinants of health (SBDH) play a crucial role in health outcomes and are frequently documented in clinical text. Automatically extracting SBDH information from clinical text relies on publicly available good-quality datasets. However, existing SBDH datasets exhibit substantial limitations in their availability and coverage. In this study, we introduce Synth-SBDH, a novel synthetic dataset with detailed SBDH annotations, encompassing status, temporal information, and rationale across 15 SBDH categories. We showcase the utility of Synth-SBDH on three tasks using real-world clinical datasets from two distinct hospital settings, highlighting its versatility, generalizability, and distillation capabilities. Models trained on Synth-SBDH consistently outperform counterparts with no Synth-SBDH training, achieving up to 63.75% macro-F improvements. Additionally, Synth-SBDH proves effective for rare SBDH categories and under-resource constraints while being substantially cheaper than expert-annotated real-world data. Human evaluation reveals a 71.06% Human-LLM alignment and uncovers areas for future refinements.
Key facts. Cited by 3 papers in the map (data through 7 Oct 2026). Placed in Medical synthetic data and agents, one of 13 directions in Synthetic data and self-improvement for LLMs. Builds on 34 of its 97 references that are in the map. First posted on arXiv 10 Jun 2024.
Builds on
34 of 97 references.
References · 34
- 2023GPT-4 Technical Reportcited by 18,132
- 2019RoBERTa: A Robustly Optimized BERT Pretraining Approachcited by 13,266
- 2023Mamba: Linear-Time Sequence Modeling with Selective State Spacescited by 4,616
- 2022Scaling Instruction-Finetuned Language Modelscited by 2,997
- 2022Self-Instruct: Aligning Language Models with Self-Generated Instructionscited by 2,674
- 2022Large Language Models Encode Clinical Knowledgecited by 1,807
- 2023MetaGPT: Meta Programming for A Multi-Agent Collaborative Frameworkcited by 1,761
- 2020Making Pre-trained Language Models Better Few-shot Learnerscited by 1,255
- 2023Distilling Step-by-Step! Outperforming Larger Language Models with Less Training Data and Smaller Model Sizescited by 710
- 2023Capabilities of GPT-4 on Medical Challenge Problemscited by 630
- 2022ToxiGen: A Large-Scale Machine-Generated Dataset for Adversarial and Implicit Hate Speech Detectioncited by 419
- 2023Towards Expert-Level Medical Question Answering with Large Language Modelscited by 382
22 more
- 2022Large Language Models are Better Reasoners with Self-Verificationcited by 304
- 2023Language Modeling Is Compressioncited by 225
- 2021Generating Datasets with Pretrained Language Modelscited by 192
- 2021GPT3Mix: Leveraging Large-scale Language Models for Text Augmentationcited by 185
- 2023InstructUIE: Multi-task Instruction Tuning for Unified Information Extractioncited by 167
- 2023Increasing Diversity While Maintaining Accuracy: Text Data Generation with Large Language Models and Human Interventionscited by 121
- 2021Medically Aware GPT-3 as a Data Generator for Medical Dialogue Summarizationcited by 76
- 2021Prompt-Learning for Fine-Grained Entity Typingcited by 62
- 2023Large Language Models to Identify Social Determinants of Health in Electronic Health Recordscited by 55
- 2023Publicly Shareable Clinical Large Language Model Built on Synthetic Clinical Notescited by 51
- 2022Data Augmentation for Intent Classification with Off-the-shelf Large Language Modelscited by 49
- 2023NoteChat: A Dataset of Synthetic Doctor-Patient Conversations Conditioned on Clinical Notescited by 48
- 2024Addressing cognitive bias in medical language modelscited by 34
- 2023Two Directions for Clinical Data Generation with Large Language Models: Data-to-Label and Label-to-Datacited by 26
- 2024ClinicalMamba: A Generative Clinical Language Model on Longitudinal Clinical Notescited by 22
- 2023The 2022 n2c2/UW Shared Task on Extracting Social Determinants of Healthcited by 21
- 2021Social and behavioral determinants of health in the era of artificial intelligence with electronic health records: A scoping reviewcited by 8
- 2022Leveraging Natural Language Processing to Augment Structured Social Determinants of Health Data in the Electronic Health Recordcited by 7
- 2023Improving Small Language Models on PubMedQA via Generative Data Augmentationcited by 6
- 2022Associations Between Natural Language Processing (NLP) Enriched Social Determinants of Health and Suicide Death among US Veteranscited by 5
- 2023SDOH-NLI: a Dataset for Inferring Social Determinants of Health from Clinical Notescited by 4
- 2024Extracting Social Determinants of Health from Pediatric Patient Notes Using Large Language Models: Novel Corpus and Methodscited by 4
Built on by
Citing papers per year: 2024: 1; 2025: 0; 2026: 2.
3 papers.
- 2024Disease Entity Recognition and Normalization is Improved with Large Language Model Derived Synthetic Normalized Mentionscited by 3
- 2026Systematic Evaluation of the Quality of Synthetic Clinical Notes Rephrased by LLMs at Million-Note Scalecited by 0
- 2026Clinical Communication Processing with Models Trained on LLM-Generated Synthetic Data: A Structured Survey and Novel Application Case Studiescited by 0
- 2026Clinical Communication Processing with Models Trained on LLM-Generated Synthetic Data: A Structured Survey and Novel Application Case Studies6 Aug 2026
- 2026Systematic Evaluation of the Quality of Synthetic Clinical Notes Rephrased by LLMs at Million-Note Scale18 May 2026
- 2024Disease Entity Recognition and Normalization is Improved with Large Language Model Derived Synthetic Normalized Mentions10 Oct 2024
Similar, not cited
Close in wording, no citation either way
- 2025Spurious Correlations and Beyond: Understanding and Mitigating Shortcut Learning in SDOH Extraction with Large Language Models
- 2025Social Determinants of Health Prediction for ICD-9 Code with Reasoning Models
- 2025DualAlign: Generating Clinically Grounded Synthetic Data
- 2025A Multi-Stage Large Language Model Framework for Extracting Suicide-Related Social Determinants of Health
- 2026Marrying Generative Model of Healthcare Events with Digital Twin of Social Determinants of Health for Disease Reasoning
- 2023From Classification to Clinical Insights: Towards Analyzing and Reasoning About Mobile and Behavioral Health Data With Large Language Models
- 2025A Scoping Review of Synthetic Data Generation by Language Models in Biomedical Research and Application: Data Utility and Quality Perspectives
- 2026Structured Insight from Unstructured Data: Large Language Models for SDOH-Driven Diabetes Risk Prediction