Can LLMs Correct Physicians, Yet? Investigating Effective Interaction Methods in the Medical Domain
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Abstract (arXiv)
We explore the potential of Large Language Models (LLMs) to assist and potentially correct physicians in medical decision-making tasks. We evaluate several LLMs, including Meditron, Llama2, and Mistral, to analyze the ability of these models to interact effectively with physicians across different scenarios. We consider questions from PubMedQA and several tasks, ranging from binary (yes/no) responses to long answer generation, where the answer of the model is produced after an interaction with a physician. Our findings suggest that prompt design significantly influences the downstream accuracy of LLMs and that LLMs can provide valuable feedback to physicians, challenging incorrect diagnoses and contributing to more accurate decision-making. For example, when the physician is accurate 38% of the time, Mistral can produce the correct answer, improving accuracy up to 74% depending on the prompt being used, while Llama2 and Meditron models exhibit greater sensitivity to prompt choice. Our analysis also uncovers the challenges of ensuring that LLM-generated suggestions are pertinent and useful, emphasizing the need for further research in this area.
Key facts. Cited by 7 papers in the map (data through 7 Oct 2026). Builds on 12 of its 24 references that are in the map. First posted on arXiv 29 Mar 2024.
Builds on
12 of 24 references.
References · 12
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- 2023Can Generalist Foundation Models Outcompete Special-Purpose Tuning? Case Study in Medicinecited by 319
- 2023MedAgents: Large Language Models as Collaborators for Zero-shot Medical Reasoningcited by 311
- 2022Can large language models reason about medical questions?cited by 194
- 2023Empowering Psychotherapy with Large Language Models: Cognitive Distortion Detection through Diagnosis of Thought Promptingcited by 31
- 2024Few shot chain-of-thought driven reasoning to prompt LLMs for open ended medical question answeringcited by 31
- 2022Analogy Generation by Prompting Large Language Models: A Case Study of InstructGPTcited by 27
- 2023The Magic of IF: Investigating Causal Reasoning Abilities in Large Language Models of Codecited by 21
- 2023ChatGPT-HealthPrompt. Harnessing the Power of XAI in Prompt-Based Healthcare Decision Support using ChatGPTcited by 5
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Citing papers per year: 2024: 4; 2025: 3.
7 papers.
- 2024Fairness Testing of Large Language Models in Role-Playingcited by 10
- 2024Gradient Boosting Decision Trees on Medical Diagnosis over Tabular Datacited by 4
- 2024XAI4LLM. Let Machine Learning Models and LLMs Collaborate for Enhanced In-Context Learning in Healthcarecited by 2
- 2025The Epistemological Consequences of Large Language Models: Rethinking collective intelligence and institutional knowledgecited by 2
- 2024Language Models And A Second Opinion Use Case: The Pocket Professionalcited by 1
- 2025Zoom In Disparities in Healthcare LLM Q&Acited by 1
- 2025Investigating LLM Capabilities on Long Context Comprehension for Medical Question Answeringcited by 0
- 2025The Epistemological Consequences of Large Language Models: Rethinking collective intelligence and institutional knowledge22 Dec 2025
- 2025Investigating LLM Capabilities on Long Context Comprehension for Medical Question Answering21 Oct 2025
- 2025Zoom In Disparities in Healthcare LLM Q&A20 Oct 2025
- 2024Fairness Testing of Large Language Models in Role-Playing1 Nov 2024
- 2024Language Models And A Second Opinion Use Case: The Pocket Professional27 Oct 2024
- 2024Gradient Boosting Decision Trees on Medical Diagnosis over Tabular Data25 Sep 2024
- 2024XAI4LLM. Let Machine Learning Models and LLMs Collaborate for Enhanced In-Context Learning in Healthcare10 May 2024