Editing Factual Knowledge and Explanatory Ability of Medical Large Language Models
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Abstract (arXiv)
Model editing aims to precisely alter the behaviors of large language models (LLMs) in relation to specific knowledge, while leaving unrelated knowledge intact. This approach has proven effective in addressing issues of hallucination and outdated information in LLMs. However, the potential of using model editing to modify knowledge in the medical field remains largely unexplored, even though resolving hallucination is a pressing need in this area. Our observations indicate that current methods face significant challenges in dealing with specialized and complex knowledge in medical domain. Therefore, we propose MedLaSA, a novel Layer-wise Scalable Adapter strategy for medical model editing. MedLaSA harnesses the strengths of both adding extra parameters and locate-then-edit methods for medical model editing. We utilize causal tracing to identify the association of knowledge in neurons across different layers, and generate a corresponding scale set from the association value for each piece of knowledge. Subsequently, we incorporate scalable adapters into the dense layers of LLMs. These adapters are assigned scaling values based on the corresponding specific knowledge, which allows for the adjustment of the adapter's weight and rank. The more similar the content, the more consistent the scale between them. This ensures precise editing of semantically identical knowledge while avoiding impact on unrelated knowledge. To evaluate the editing impact on the behaviours of LLMs, we propose two model editing studies for medical domain: (1) editing factual knowledge for medical specialization and (2) editing the explanatory ability for complex knowledge. We build two novel medical benchmarking datasets and introduce a series of challenging and comprehensive metrics. Extensive experiments on medical LLMs demonstrate the editing efficiency of MedLaSA, without affecting unrelated knowledge.
Key facts. Cited by 10 papers in the map (data through 7 Oct 2026). Builds on 27 of its 50 references that are in the map. First posted on arXiv 28 Feb 2024.
Builds on
27 of 50 references.
References · 27
- 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,084
- 2023Llama 2: Open Foundation and Fine-Tuned Chat Modelscited by 12,865
- 2022Locating and Editing Factual Associations in GPTcited by 2,609
- 2019BioBERT: a pre-trained biomedical language representation model for biomedical text miningcited by 1,935
- 2019Language Models as Knowledge Bases?cited by 1,922
- 2020Transformer Feed-Forward Layers Are Key-Value Memoriescited by 1,307
- 2023A Survey on Evaluation of Large Language Modelscited by 1,227
- 2022Mass-Editing Memory in a Transformercited by 976
- 2019RotatE: Knowledge Graph Embedding by Relational Rotation in Complex Spacecited by 893
- 2021Editing Factual Knowledge in Language Modelscited by 548
- 2022Transformer Feed-Forward Layers Build Predictions by Promoting Concepts in the Vocabulary Spacecited by 522
- 2022Memory-Based Model Editing at Scalecited by 443
15 more
- 2023Editing Large Language Models: Problems, Methods, and Opportunitiescited by 367
- 2023HaluEval: A Large-Scale Hallucination Evaluation Benchmark for Large Language Modelscited by 329
- 2023ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledgecited by 324
- 2023Can We Edit Factual Knowledge by In-Context Learning?cited by 284
- 2022Aging with GRACE: Lifelong Model Editing with Discrete Key-Value Adaptorscited by 267
- 2023Transformer-Patcher: One Mistake worth One Neuroncited by 196
- 2023Knowledge Editing for Large Language Models: A Surveycited by 189
- 2023Large Language Models for Generative Information Extraction: A Surveycited by 183
- 2023PMET: Precise Model Editing in a Transformercited by 170
- 2023A Survey of Large Language Models for Healthcare: from Data, Technology, and Applications to Accountability and Ethicscited by 162
- 2023When MOE Meets LLMs: Parameter Efficient Fine-tuning for Multi-task Medical Applicationscited by 110
- 2023MELO: Enhancing Model Editing with Neuron-Indexed Dynamic LoRAcited by 80
- 2023DEPN: Detecting and Editing Privacy Neurons in Pretrained Language Modelscited by 75
- 2023Trends in Integration of Knowledge and Large Language Models: A Survey and Taxonomy of Methods, Benchmarks, and Applicationscited by 28
- 2024AutoPRM: Automating Procedural Supervision for Multi-Step Reasoning via Controllable Question Decompositioncited by 24
Built on by
Citing papers per year: 2024: 4; 2025: 4; 2026: 2.
10 papers.
- 2024Decoding by Contrasting Knowledge: Enhancing LLMs' Confidence on Edited Factscited by 36
- 2024Can Knowledge Editing Really Correct Hallucinations?cited by 28
- 2024Can Editing LLMs Inject Harm?cited by 22
- 2024Is Factuality Enhancement a Free Lunch For LLMs? Better Factuality Can Lead to Worse Context-Faithfulnesscited by 17
- 2025MedREK: Retrieval-Based Editing for Medical LLMs with Key-Aware Promptscited by 5
- 2026BAS: A Decision-Theoretic Approach to Evaluating Large Language Model Confidencecited by 5
- 2025A Scoping Review of Natural Language Processing in Addressing Medically Inaccurate Information: Errors, Misinformation, and Hallucinationcited by 2
- 2025Triadic Fusion of Cognitive, Functional, and Causal Dimensions for Explainable LLMs: The TAXAL Frameworkcited by 1
- 2025ADS-Edit: A Multimodal Knowledge Editing Dataset for Autonomous Driving Systemscited by 0
- 2026MedKIT: Evaluating Knowledge Integration and Generalization in Large Language Modelscited by 0
- 2026MedKIT: Evaluating Knowledge Integration and Generalization in Large Language Models29 Sep 2026
- 2026BAS: A Decision-Theoretic Approach to Evaluating Large Language Model Confidence3 Apr 2026
- 2025MedREK: Retrieval-Based Editing for Medical LLMs with Key-Aware Prompts15 Oct 2025
- 2025Triadic Fusion of Cognitive, Functional, and Causal Dimensions for Explainable LLMs: The TAXAL Framework5 Sep 2025
- 2025A Scoping Review of Natural Language Processing in Addressing Medically Inaccurate Information: Errors, Misinformation, and Hallucination16 Apr 2025
- 2025ADS-Edit: A Multimodal Knowledge Editing Dataset for Autonomous Driving Systems26 Mar 2025
- 2024Can Knowledge Editing Really Correct Hallucinations?21 Oct 2024
- 2024Can Editing LLMs Inject Harm?29 Jul 2024
- 2024Decoding by Contrasting Knowledge: Enhancing LLMs' Confidence on Edited Facts19 May 2024
- 2024Is Factuality Enhancement a Free Lunch For LLMs? Better Factuality Can Lead to Worse Context-Faithfulness30 Mar 2024