Towards Interpretable Classification of Leukocytes based on Deep Learning
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Abstract (arXiv)
Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify cells with high accuracy where the human observer has little chance to discriminate cells. In order to better integrate these workflows into the clinical decision making process, this work investigates the calibration of confidence estimation for the automated classification of leukocytes. In addition, different visual explanation approaches are compared, which should bring machine decision making closer to professional healthcare applications. Furthermore, we were able to identify general detection patterns in neural networks and demonstrate the utility of the presented approaches in different scenarios of blood cell analysis.
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References · 22
- 2016Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localizationcited by 6,690
- 2016"Why Should I Trust You?": Explaining the Predictions of Any Classifiercited by 5,040
- 2017On Calibration of Modern Neural Networkscited by 4,860
- 2015Learning Deep Features for Discriminative Localizationcited by 2,430
- 2013Deep Inside Convolutional Networks: Visualising Image Classification Models and Saliency Mapscited by 2,348
- 2013Visualizing and Understanding Convolutional Networkscited by 2,278
- 2016Identity Mappings in Deep Residual Networkscited by 1,960
- 2017Interpretability Beyond Feature Attribution: Quantitative Testing with Concept Activation Vectors (TCAV)cited by 1,309
- 2014Striving for Simplicity: The All Convolutional Netcited by 983
- 2017Interpretable Explanations of Black Boxes by Meaningful Perturbationcited by 611
- 2017Deep Learning for Medical Image Analysiscited by 399
- 2019Unmasking Clever Hans Predictors and Assessing What Machines Really Learncited by 359
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- 2019Beyond temperature scaling: Obtaining well-calibrated multiclass probabilities with Dirichlet calibrationcited by 359
- 2016Model-Agnostic Interpretability of Machine Learningcited by 219
- 2018An overview of deep learning in medical imaging focusing on MRIcited by 140
- 2019Smooth Grad-CAM++: An Enhanced Inference Level Visualization Technique for Deep Convolutional Neural Network Modelscited by 118
- 2017Towards better understanding of gradient-based attribution methods for Deep Neural Networkscited by 51
- 2020DeepOpht: Medical Report Generation for Retinal Images via Deep Models and Visual Explanationcited by 43
- 2022Guidelines and Evaluation of Clinical Explainable AI in Medical Image Analysiscited by 34
- 2018Local Interpretable Model-agnostic Explanations of Bayesian Predictive Models via Kullback-Leibler Projectionscited by 10
- 2020Interpretable and synergistic deep learning for visual explanation and statistical estimations of segmentation of disease features from medical imagescited by 3
- 2022Outlier Detection using Self-Organizing Maps for Automated Blood Cell Analysiscited by 1
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