AutoProSAM: Automated Prompting SAM for 3D Multi-Organ Segmentation
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Abstract (arXiv)
Segment Anything Model (SAM) is one of the pioneering prompt-based foundation models for image segmentation and has been rapidly adopted for various medical imaging applications. However, in clinical settings, creating effective prompts is notably challenging and time-consuming, requiring the expertise of domain specialists such as physicians. This requirement significantly diminishes SAM's primary advantage, its interactive capability with end users, in medical applications. Moreover, recent studies have indicated that SAM, originally designed for 2D natural images, performs suboptimally on 3D medical image segmentation tasks. This subpar performance is attributed to the domain gaps between natural and medical images and the disparities in spatial arrangements between 2D and 3D images, particularly in multi-organ segmentation applications. To overcome these challenges, we present a novel technique termed AutoProSAM. This method automates 3D multi-organ CT-based segmentation by leveraging SAM's foundational model capabilities without relying on domain experts for prompts. The approach utilizes parameter-efficient adaptation techniques to adapt SAM for 3D medical imagery and incorporates an effective automatic prompt learning paradigm specific to this domain. By eliminating the need for manual prompts, it enhances SAM's capabilities for 3D medical image segmentation and achieves state-of-the-art (SOTA) performance in CT-based multi-organ segmentation tasks. The code is in this hrefhttps://github.com/ChengyinLee/AutoProSAM2024link.
Key facts. Cited by 19 papers in the map (data through 14 Oct 2026). Builds on 29 of its 50 references that are in the map. First posted on arXiv 28 Aug 2023.
Builds on
29 of 50 references.
References · 29
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17 more
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- 2023AutoSAM: Adapting SAM to Medical Images by Overloading the Prompt Encodercited by 70
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Citing papers per year: 2023: 2; 2024: 5; 2025: 8; 2026: 4.
19 papers.
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- 2023MA-SAM: Modality-agnostic SAM Adaptation for 3D Medical Image Segmentationcited by 82
- 2024Unleashing the Potential of SAM for Medical Adaptation via Hierarchical Decodingcited by 48
- 2024Foundation Models for Biomedical Image Segmentation: A Surveycited by 28
- 2025Diffusion-empowered AutoPrompt MedSAMcited by 10
- 2023Enhancing the Reliability of Segment Anything Model for Auto-Prompting Medical Image Segmentation with Uncertainty Rectificationcited by 8
- 2024MulModSeg: Enhancing Unpaired Multi-Modal Medical Image Segmentation with Modality-Conditioned Text Embedding and Alternating Trainingcited by 6
- 2024SAMCT: Segment Any CT Allowing Labor-Free Task-Indicator Promptscited by 5
- 2025FluenceFormer: Transformer-Driven Multi-Beam Fluence Map Regression for Radiotherapy Planningcited by 4
- 2025Prompt Engineering in Segment Anything Model: Methodologies, Applications, and Emerging Challengescited by 3
- 2025Prompt learning with bounding box constraints for medical image segmentationcited by 2
- 2025Supervise Less, See More: Training-free Nuclear Instance Segmentation with Prototype-Guided Promptingcited by 2
- 2024Leveraging SAM for Single-Source Domain Generalization in Medical Image Segmentationcited by 1
7 more
- 2025BiPVL-Seg: Bidirectional Progressive Vision-Language Fusion with Global-Local Alignment for Medical Image Segmentationcited by 1
- 2025A Probabilistic Segment Anything Model for Ambiguity-Aware Medical Image Segmentationcited by 1
- 2025SwinTF3D: A Lightweight Multimodal Fusion Approach for Text-Guided 3D Medical Image Segmentationcited by 0
- 2026BLO-Inst: Bi-Level Optimization Based Alignment of YOLO and SAM for Robust Instance Segmentationcited by 0
- 2026BAP-MOS: Bandit-Based Adaptive Prompting for Boundary-Sensitive Multi-Organ Segmentationcited by 0
- 2026MedPlex: Deep Vision-Language Co-Adaptation for Clinically Grounded Medical Segmentationcited by 0
- 2026Bootstrapping a 4D LiDAR Annotation Tool from Video Foundation Modelscited by 0
- 2026Bootstrapping a 4D LiDAR Annotation Tool from Video Foundation Models26 Aug 2026
- 2026MedPlex: Deep Vision-Language Co-Adaptation for Clinically Grounded Medical Segmentation13 Aug 2026
- 2026BAP-MOS: Bandit-Based Adaptive Prompting for Boundary-Sensitive Multi-Organ Segmentation8 Aug 2026
- 2026BLO-Inst: Bi-Level Optimization Based Alignment of YOLO and SAM for Robust Instance Segmentation29 Jan 2026
- 2025SwinTF3D: A Lightweight Multimodal Fusion Approach for Text-Guided 3D Medical Image Segmentation28 Dec 2025
- 2025FluenceFormer: Transformer-Driven Multi-Beam Fluence Map Regression for Radiotherapy Planning27 Dec 2025
- 2025Supervise Less, See More: Training-free Nuclear Instance Segmentation with Prototype-Guided Prompting25 Nov 2025
- 2025A Probabilistic Segment Anything Model for Ambiguity-Aware Medical Image Segmentation6 Sep 2025
- 2025Prompt Engineering in Segment Anything Model: Methodologies, Applications, and Emerging Challenges13 Jul 2025
- 2025Prompt learning with bounding box constraints for medical image segmentation3 Jul 2025
- 2025BiPVL-Seg: Bidirectional Progressive Vision-Language Fusion with Global-Local Alignment for Medical Image Segmentation30 Mar 2025
- 2025Diffusion-empowered AutoPrompt MedSAM5 Feb 2025
7 more
- 2024MulModSeg: Enhancing Unpaired Multi-Modal Medical Image Segmentation with Modality-Conditioned Text Embedding and Alternating Training23 Nov 2024
- 2024Unleashing the Potential of SAM for Medical Adaptation via Hierarchical Decoding27 Mar 2024
- 2024SAMCT: Segment Any CT Allowing Labor-Free Task-Indicator Prompts20 Mar 2024
- 2024Foundation Models for Biomedical Image Segmentation: A Survey15 Jan 2024
- 2024Leveraging SAM for Single-Source Domain Generalization in Medical Image Segmentation4 Jan 2024
- 2023Enhancing the Reliability of Segment Anything Model for Auto-Prompting Medical Image Segmentation with Uncertainty Rectification17 Nov 2023
- 2023MA-SAM: Modality-agnostic SAM Adaptation for 3D Medical Image Segmentation16 Sep 2023
- 2023MA-SAM: Modality-agnostic SAM Adaptation for 3D Medical Image Segmentationcited by 82
- 2024Unleashing the Potential of SAM for Medical Adaptation via Hierarchical Decodingcited by 48
- 2024Foundation Models for Biomedical Image Segmentation: A Surveycited by 28
- 2025Diffusion-empowered AutoPrompt MedSAMcited by 10
- 2023Enhancing the Reliability of Segment Anything Model for Auto-Prompting Medical Image Segmentation with Uncertainty Rectificationcited by 8
- 2024MulModSeg: Enhancing Unpaired Multi-Modal Medical Image Segmentation with Modality-Conditioned Text Embedding and Alternating Trainingcited by 6
- 2024SAMCT: Segment Any CT Allowing Labor-Free Task-Indicator Promptscited by 5
- 2025FluenceFormer: Transformer-Driven Multi-Beam Fluence Map Regression for Radiotherapy Planningcited by 4
- 2025Prompt Engineering in Segment Anything Model: Methodologies, Applications, and Emerging Challengescited by 3
- 2025Prompt learning with bounding box constraints for medical image segmentationcited by 2
- 2025Supervise Less, See More: Training-free Nuclear Instance Segmentation with Prototype-Guided Promptingcited by 2
- 2024Leveraging SAM for Single-Source Domain Generalization in Medical Image Segmentationcited by 1
12 most cited of 19 All 19 (JSON)
- 2026Bootstrapping a 4D LiDAR Annotation Tool from Video Foundation Models26 Aug 2026
- 2026MedPlex: Deep Vision-Language Co-Adaptation for Clinically Grounded Medical Segmentation13 Aug 2026
- 2026BAP-MOS: Bandit-Based Adaptive Prompting for Boundary-Sensitive Multi-Organ Segmentation8 Aug 2026
- 2026BLO-Inst: Bi-Level Optimization Based Alignment of YOLO and SAM for Robust Instance Segmentation29 Jan 2026
- 2025SwinTF3D: A Lightweight Multimodal Fusion Approach for Text-Guided 3D Medical Image Segmentation28 Dec 2025
- 2025FluenceFormer: Transformer-Driven Multi-Beam Fluence Map Regression for Radiotherapy Planning27 Dec 2025
- 2025Supervise Less, See More: Training-free Nuclear Instance Segmentation with Prototype-Guided Prompting25 Nov 2025
- 2025A Probabilistic Segment Anything Model for Ambiguity-Aware Medical Image Segmentation6 Sep 2025
- 2025Prompt Engineering in Segment Anything Model: Methodologies, Applications, and Emerging Challenges13 Jul 2025
- 2025Prompt learning with bounding box constraints for medical image segmentation3 Jul 2025
- 2025BiPVL-Seg: Bidirectional Progressive Vision-Language Fusion with Global-Local Alignment for Medical Image Segmentation30 Mar 2025
- 2025Diffusion-empowered AutoPrompt MedSAM5 Feb 2025
12 newest of 19 All 19 (JSON)