mlsanityData to 14 Oct 2026

AutoProSAM: Automated Prompting SAM for 3D Multi-Organ Segmentation

arXiv 2308.14936 ↗First posted 28 Aug 2023cs.CV cs.AIcited by 19

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Abstract (arXiv)

Segment Anything Model (SAM) is one of the pioneering prompt-based foundation models for image segmentation and has been rapidly adopted for various medical imaging applications. However, in clinical settings, creating effective prompts is notably challenging and time-consuming, requiring the expertise of domain specialists such as physicians. This requirement significantly diminishes SAM's primary advantage, its interactive capability with end users, in medical applications. Moreover, recent studies have indicated that SAM, originally designed for 2D natural images, performs suboptimally on 3D medical image segmentation tasks. This subpar performance is attributed to the domain gaps between natural and medical images and the disparities in spatial arrangements between 2D and 3D images, particularly in multi-organ segmentation applications. To overcome these challenges, we present a novel technique termed AutoProSAM. This method automates 3D multi-organ CT-based segmentation by leveraging SAM's foundational model capabilities without relying on domain experts for prompts. The approach utilizes parameter-efficient adaptation techniques to adapt SAM for 3D medical imagery and incorporates an effective automatic prompt learning paradigm specific to this domain. By eliminating the need for manual prompts, it enhances SAM's capabilities for 3D medical image segmentation and achieves state-of-the-art (SOTA) performance in CT-based multi-organ segmentation tasks. The code is in this hrefhttps://github.com/ChengyinLee/AutoProSAM2024link.

Key facts. Cited by 19 papers in the map (data through 14 Oct 2026). Builds on 29 of its 50 references that are in the map. First posted on arXiv 28 Aug 2023.

Builds on

29 of 50 references.

References · 29

  1. 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,744
  2. 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 30,186
  3. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,713
  4. 2014Microsoft COCO: Common Objects in Contextcited by 17,608
  5. 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,380
  6. 2023Segment Anythingcited by 8,234
  7. 2023DINOv2: Learning Robust Visual Features without Supervisioncited by 7,974
  8. 2021Pre-train, Prompt, and Predict: A Systematic Survey of Prompting Methods in Natural Language Processingcited by 2,234
  9. 2022Visual Prompt Tuningcited by 1,681
  10. 2020Rethinking Semantic Segmentation from a Sequence-to-Sequence Perspective with Transformerscited by 1,369
  11. 2021BitFit: Simple Parameter-efficient Fine-tuning for Transformer-based Masked Language-modelscited by 1,245
  12. 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 959
17 more
  1. 2019Self-supervised Visual Feature Learning with Deep Neural Networks: A Surveycited by 657
  2. 2019UNet++: Redesigning Skip Connections to Exploit Multiscale Features in Image Segmentationcited by 586
  3. 2023Medical SAM Adapter: Adapting Segment Anything Model for Medical Image Segmentationcited by 490
  4. 2021Recent Advances in Natural Language Processing via Large Pre-Trained Language Models: A Surveycited by 463
  5. 2021Self-Supervised Pre-Training of Swin Transformers for 3D Medical Image Analysiscited by 422
  6. 2020Parameter-Efficient Transfer Learning with Diff Pruningcited by 352
  7. 2022AMOS: A Large-Scale Abdominal Multi-Organ Benchmark for Versatile Medical Image Segmentationcited by 351
  8. 2023Segment Anything Model for Medical Image Analysis: an Experimental Studycited by 291
  9. 2023Customized Segment Anything Model for Medical Image Segmentationcited by 280
  10. 2022ST-Adapter: Parameter-Efficient Image-to-Video Transfer Learningcited by 193
  11. 2021nnFormer: Interleaved Transformer for Volumetric Segmentationcited by 180
  12. 2019Evaluation of Algorithms for Multi-Modality Whole Heart Segmentation: An Open-Access Grand Challengecited by 100
  13. 2021Contrastive Learning with Stronger Augmentationscited by 100
  14. 2018Deep learning to achieve clinically applicable segmentation of head and neck anatomy for radiotherapycited by 77
  15. 2023AutoSAM: Adapting SAM to Medical Images by Overloading the Prompt Encodercited by 70
  16. 2023A Comprehensive Survey on Segment Anything Model for Vision and Beyondcited by 64
  17. 2022FocalUNETR: A Focal Transformer for Boundary-aware Segmentation of CT Imagescited by 9

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Cited by year (2026 to 14 Oct)

Citing papers per year: 2023: 2; 2024: 5; 2025: 8; 2026: 4.

19 papers.

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  1. 2023MA-SAM: Modality-agnostic SAM Adaptation for 3D Medical Image Segmentationcited by 82
  2. 2024Unleashing the Potential of SAM for Medical Adaptation via Hierarchical Decodingcited by 48
  3. 2024Foundation Models for Biomedical Image Segmentation: A Surveycited by 28
  4. 2025Diffusion-empowered AutoPrompt MedSAMcited by 10
  5. 2023Enhancing the Reliability of Segment Anything Model for Auto-Prompting Medical Image Segmentation with Uncertainty Rectificationcited by 8
  6. 2024MulModSeg: Enhancing Unpaired Multi-Modal Medical Image Segmentation with Modality-Conditioned Text Embedding and Alternating Trainingcited by 6
  7. 2024SAMCT: Segment Any CT Allowing Labor-Free Task-Indicator Promptscited by 5
  8. 2025FluenceFormer: Transformer-Driven Multi-Beam Fluence Map Regression for Radiotherapy Planningcited by 4
  9. 2025Prompt Engineering in Segment Anything Model: Methodologies, Applications, and Emerging Challengescited by 3
  10. 2025Prompt learning with bounding box constraints for medical image segmentationcited by 2
  11. 2025Supervise Less, See More: Training-free Nuclear Instance Segmentation with Prototype-Guided Promptingcited by 2
  12. 2024Leveraging SAM for Single-Source Domain Generalization in Medical Image Segmentationcited by 1
7 more
  1. 2025BiPVL-Seg: Bidirectional Progressive Vision-Language Fusion with Global-Local Alignment for Medical Image Segmentationcited by 1
  2. 2025A Probabilistic Segment Anything Model for Ambiguity-Aware Medical Image Segmentationcited by 1
  3. 2025SwinTF3D: A Lightweight Multimodal Fusion Approach for Text-Guided 3D Medical Image Segmentationcited by 0
  4. 2026BLO-Inst: Bi-Level Optimization Based Alignment of YOLO and SAM for Robust Instance Segmentationcited by 0
  5. 2026BAP-MOS: Bandit-Based Adaptive Prompting for Boundary-Sensitive Multi-Organ Segmentationcited by 0
  6. 2026MedPlex: Deep Vision-Language Co-Adaptation for Clinically Grounded Medical Segmentationcited by 0
  7. 2026Bootstrapping a 4D LiDAR Annotation Tool from Video Foundation Modelscited by 0