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Exploring the Trade-Offs: Unified Large Language Models vs Local Fine-Tuned Models for Highly-Specific Radiology NLI Task

arXiv 2304.09138 ↗First posted 18 Apr 2023cs.CLcited by 32

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Abstract (arXiv)

Recently, ChatGPT and GPT-4 have emerged and gained immense global attention due to their unparalleled performance in language processing. Despite demonstrating impressive capability in various open-domain tasks, their adequacy in highly specific fields like radiology remains untested. Radiology presents unique linguistic phenomena distinct from open-domain data due to its specificity and complexity. Assessing the performance of large language models (LLMs) in such specific domains is crucial not only for a thorough evaluation of their overall performance but also for providing valuable insights into future model design directions: whether model design should be generic or domain-specific. To this end, in this study, we evaluate the performance of ChatGPT/GPT-4 on a radiology NLI task and compare it to other models fine-tuned specifically on task-related data samples. We also conduct a comprehensive investigation on ChatGPT/GPT-4's reasoning ability by introducing varying levels of inference difficulty. Our results show that 1) GPT-4 outperforms ChatGPT in the radiology NLI task; 2) other specifically fine-tuned models require significant amounts of data samples to achieve comparable performance to ChatGPT/GPT-4. These findings demonstrate that constructing a generic model that is capable of solving various tasks across different domains is feasible.

Key facts. Cited by 32 papers in the map (data through 7 Oct 2026). Builds on 37 of its 56 references that are in the map. First posted on arXiv 18 Apr 2023.

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37 of 56 references.

References · 37

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Citing papers per year: 2023: 17; 2024: 10; 2025: 5.

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  1. 2024Revolutionizing Finance with LLMs: An Overview of Applications and Insightscited by 88
  2. 2023Review of Large Vision Models and Visual Prompt Engineeringcited by 77
  3. 2024Understanding LLMs: A Comprehensive Overview from Training to Inferencecited by 58
  4. 2023Prompt Engineering for Healthcare: Methodologies and Applicationscited by 52
  5. 2023Radiology-GPT: A Large Language Model for Radiologycited by 44
  6. 2023Radiology-Llama2: Best-in-Class Large Language Model for Radiologycited by 42
  7. 2023Artificial General Intelligence for Medical Imaging Analysiscited by 32
  8. 2023Exploring the Boundaries of GPT-4 in Radiologycited by 31
  9. 2024Data-Centric Foundation Models in Computational Healthcare: A Surveycited by 27
  10. 2023ChatABL: Abductive Learning via Natural Language Interaction with ChatGPTcited by 26
  11. 2023Segment Anything Model (SAM) for Radiation Oncologycited by 24
  12. 2023Exploring New Frontiers in Agricultural NLP: Investigating the Potential of Large Language Models for Food Applicationscited by 21
20 more
  1. 2023Holistic Evaluation of GPT-4V for Biomedical Imagingcited by 19
  2. 2023RadOnc-GPT: A Large Language Model for Radiation Oncologycited by 18
  3. 2023Evaluating Large Language Models for Radiology Natural Language Processingcited by 12
  4. 2024Towards Next-Generation Medical Agent: How o1 is Reshaping Decision-Making in Medical Scenarioscited by 10
  5. 2024Progressive Inference: Explaining Decoder-Only Sequence Classification Models Using Intermediate Predictionscited by 6
  6. 2023Hierarchical Semantic Tree Concept Whitening for Interpretable Image Classificationcited by 5
  7. 2023Chat2Brain: A Method for Mapping Open-Ended Semantic Queries to Brain Activation Mapscited by 5
  8. 2023Benchmarking a foundation LLM on its ability to re-label structure names in accordance with the AAPM TG-263 reportcited by 5
  9. 2024Analysing zero-shot temporal relation extraction on clinical notes using temporal consistencycited by 5
  10. 2024Can we obtain significant success in RST discourse parsing by using Large Language Models?cited by 4
  11. 2025RadOnc-GPT: An Autonomous LLM Agent for Real-Time Patient Outcomes Labeling at Scalecited by 4
  12. 2023PharmacyGPT: The AI Pharmacistcited by 3
  13. 2024Prompt2DeModel: Declarative Neuro-Symbolic Modeling with Natural Languagecited by 3
  14. 2025Large Language Models for Bioinformaticscited by 3
  15. 2025RAU: Reference-based Anatomical Understanding with Vision Language Modelscited by 3
  16. 2023Rethinking STS and NLI in Large Language Modelscited by 2
  17. 2024Retrospective Comparative Analysis of Prostate Cancer In-Basket Messages: Responses from Closed-Domain LLM vs. Clinical Teamscited by 2
  18. 2025Evaluating The Performance of Using Large Language Models to Automate Summarization of CT Simulation Orders in Radiation Oncologycited by 2
  19. 2025Predicate Renaming via Large Language Modelscited by 2
  20. 2024Evaluation of Language Models in the Medical Context Under Resource-Constrained Settingscited by 1

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