Advances in Medical Image Analysis with Vision Transformers: A Comprehensive Review
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Abstract (arXiv)
The remarkable performance of the Transformer architecture in natural language processing has recently also triggered broad interest in Computer Vision. Among other merits, Transformers are witnessed as capable of learning long-range dependencies and spatial correlations, which is a clear advantage over convolutional neural networks (CNNs), which have been the de facto standard in Computer Vision problems so far. Thus, Transformers have become an integral part of modern medical image analysis. In this review, we provide an encyclopedic review of the applications of Transformers in medical imaging. Specifically, we present a systematic and thorough review of relevant recent Transformer literature for different medical image analysis tasks, including classification, segmentation, detection, registration, synthesis, and clinical report generation. For each of these applications, we investigate the novelty, strengths and weaknesses of the different proposed strategies and develop taxonomies highlighting key properties and contributions. Further, if applicable, we outline current benchmarks on different datasets. Finally, we summarize key challenges and discuss different future research directions. In addition, we have provided cited papers with their corresponding implementations in https://github.com/mindflow-institue/Awesome-Transformer.
Key facts. Cited by 62 papers in the map (data through 7 Oct 2026). Builds on 128 of its 242 references that are in the map. First posted on arXiv 9 Jan 2023.
Builds on
128 of 242 references.
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50 most cited of 128 All 128 (JSON)
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Citing papers per year: 2023: 12; 2024: 20; 2025: 21; 2026: 9.
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- 2023Implicit Neural Representation in Medical Imaging: A Comparative Surveycited by 88
- 2023Foundational Models in Medical Imaging: A Comprehensive Survey and Future Visioncited by 74
- 2023Loss Functions in the Era of Semantic Segmentation: A Survey and Outlookcited by 33
- 2023Beyond Self-Attention: Deformable Large Kernel Attention for Medical Image Segmentationcited by 30
- 2024Evaluating LLM -- Generated Multimodal Diagnosis from Medical Images and Symptom Analysiscited by 23
- 2023A Recent Survey of Vision Transformers for Medical Image Segmentationcited by 22
- 2023Continual Learning in Medical Image Analysis: A Comprehensive Review of Recent Advancements and Future Prospectscited by 22
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- 2024Exploring the Synergies of Hybrid CNNs and ViTs Architectures for Computer Vision: A surveycited by 13
- 2023DermoSegDiff: A Boundary-aware Segmentation Diffusion Model for Skin Lesion Delineationcited by 12
- 2024xLSTM-UNet can be an Effective 2D & 3D Medical Image Segmentation Backbone with Vision-LSTM (ViL) better than its Mamba Counterpartcited by 12
- 2023Enhancing Medical Image Segmentation with TransCeption: A Multi-Scale Feature Fusion Approachcited by 11
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- 2024Comprehensive Multimodal Deep Learning Survival Prediction Enabled by a Transformer Architecture: A Multicenter Study in Glioblastomacited by 9
- 2025Recent Advances in Medical Imaging Segmentation: A Surveycited by 8
- 2024Tissue Concepts: supervised foundation models in computational pathologycited by 7
- 2025Collective Reasoning Among LLMs: A Framework for Answer Validation Without Ground Truthcited by 7
- 2023Self-supervised Few-shot Learning for Semantic Segmentation: An Annotation-free Approachcited by 6
- 2024Enhancing Answer Reliability Through Inter-Model Consensus of Large Language Modelscited by 6
- 2023Self-supervised Semantic Segmentation: Consistency over Transformationcited by 5
- 2025Medical Image Classification with KAN-Integrated Transformers and Dilated Neighborhood Attentioncited by 5
- 2024Enhancing Efficiency in Vision Transformer Networks: Design Techniques and Insightscited by 4
- 2024LHU-Net: a Lean Hybrid U-Net for Cost-efficient, High-performance Volumetric Segmentationcited by 4
- 2024Deep Learning for Pancreas Segmentation: a Systematic Reviewcited by 4
- 2024MedVisionLlama: Leveraging Pre-Trained Large Language Model Layers to Enhance Medical Image Segmentationcited by 4
- 2025A Self-supervised Multimodal Deep Learning Approach to Differentiate Post-radiotherapy Progression from Pseudoprogression in Glioblastomacited by 4
- 2026Meningioma Analysis and Diagnosis using Limited Labeled Samplescited by 4
- 2023Unlocking Fine-Grained Details with Wavelet-based High-Frequency Enhancement in Transformerscited by 3
- 2024Key Patches Are All You Need: A Multiple Instance Learning Framework For Robust Medical Diagnosiscited by 3
- 2025GONet: A Generalizable Deep Learning Model for Glaucoma Detectioncited by 3
- 2025A Hybrid Fully Convolutional CNN-Transformer Model for Inherently Interpretable Disease Detection from Retinal Fundus Imagescited by 3
- 2025MedFormer: Hierarchical Medical Vision Transformer with Content-Aware Dual Sparse Selection Attentioncited by 3
- 2024Integrating Clinical Knowledge Graphs and Gradient-Based Neural Systems for Enhanced Melanoma Diagnosis via the 7-Point Checklistcited by 2
- 2024Advances in Transformers for Robotic Applications: A Reviewcited by 2
- 2025AutoRad-Lung: A Radiomic-Guided Prompting Autoregressive Vision-Language Model for Lung Nodule Malignancy Predictioncited by 2
- 2025WoundAmbit: Bridging State-of-the-Art Semantic Segmentation and Real-World Wound Carecited by 2
- 2025Structured Spectral Graph Learning for Anomaly Classification in 3D Chest CT Scanscited by 2
- 2024Multi-modality Regional Alignment Network for Covid X-Ray Survival Prediction and Report Generationcited by 1
- 2025Med-R2: Perception and Reflection-driven Complex Reasoning for Medical Report Generationcited by 1
- 2026MTFlow: Time-Conditioned Flow Matching for Microtubule Segmentation in Noisy Microscopy Imagescited by 1
- 2024Deep Spatiotemporal Clutter Filtering of Transthoracic Echocardiographic Images: Leveraging Contextual Attention and Residual Learningcited by 0
- 2024Channel Boosted CNN-Transformer-based Multi-Level and Multi-Scale Nuclei Segmentationcited by 0
- 2024Ultrasound-Based AI for COVID-19 Detection: A Comprehensive Review of Public and Private Lung Ultrasound Datasets and Studiescited by 0
- 2024Artificial Intelligence in Pediatric Echocardiography: Exploring Challenges, Opportunities, and Clinical Applications with Explainable AI and Federated Learningcited by 0
- 2025Shape Modeling of Longitudinal Medical Images: From Diffeomorphic Metric Mapping to Deep Learningcited by 0
- 2025MERA: Multimodal and Multiscale Self-Explanatory Model with Considerably Reduced Annotation for Lung Nodule Diagnosiscited by 0
- 2025Tetrahedron-Net for Medical Image Registrationcited by 0
- 2025DuoFormer: Leveraging Hierarchical Representations by Local and Global Attention Vision Transformercited by 0
50 most cited of 62 All 62 (JSON)
- 2026Beyond Classification: Structured Supervision Aligns Visual Evidence with Medical Semantics5 Sep 2026
- 2026Vision Foundation Models in Radiology: A Scoping Review of Data, Methodology, Evaluation and Clinical Translation8 Jul 2026
- 2026Attention-Guided Fusion of 1D and 2D CNNs for Robust ECG-Based Biometric Recognition17 May 2026
- 2026Multi-Dataset Cross-Domain Knowledge Distillation for Unified Medical Image Segmentation, Classification, and Detection2 May 2026
- 2026Towards interpretable AI with quantum annealing feature selection28 Apr 2026
- 2026Interpretable Prostate Cancer Detection using a Small Cohort of MRI Images19 Mar 2026
- 2026Effect of Patch Size on Fine-Tuning Vision Transformers in Two-Dimensional and Three-Dimensional Medical Image Classification20 Feb 2026
- 2026Meningioma Analysis and Diagnosis using Limited Labeled Samples11 Feb 2026
- 2026MTFlow: Time-Conditioned Flow Matching for Microtubule Segmentation in Noisy Microscopy Images21 Jan 2026
- 2025Skin Cancer Classification: Hybrid CNN-Transformer Models with KAN-Based Fusion17 Aug 2025
- 2025TCSAFormer: Efficient Vision Transformer with Token Compression and Sparse Attention for Medical Image Segmentation6 Aug 2025
- 2025Structured Spectral Graph Learning for Anomaly Classification in 3D Chest CT Scans1 Aug 2025
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- 2025SwinECAT: A Transformer-based fundus disease classification model with Shifted Window Attention and Efficient Channel Attention29 Jul 2025
- 2025Enhancing Breast Cancer Detection with Vision Transformers and Graph Neural Networks11 Jul 2025
- 2025MedFormer: Hierarchical Medical Vision Transformer with Content-Aware Dual Sparse Selection Attention3 Jul 2025
- 2025HMSViT: A Hierarchical Masked Self-Supervised Vision Transformer for Corneal Nerve Segmentation and Diabetic Neuropathy Diagnosis24 Jun 2025
- 2025DuoFormer: Leveraging Hierarchical Representations by Local and Global Attention Vision Transformer15 Jun 2025
- 2025Recent Advances in Medical Imaging Segmentation: A Survey14 May 2025
- 2025Tetrahedron-Net for Medical Image Registration7 May 2025
- 2025MERA: Multimodal and Multiscale Self-Explanatory Model with Considerably Reduced Annotation for Lung Nodule Diagnosis27 Apr 2025
- 2025A Hybrid Fully Convolutional CNN-Transformer Model for Inherently Interpretable Disease Detection from Retinal Fundus Images11 Apr 2025
- 2025WoundAmbit: Bridging State-of-the-Art Semantic Segmentation and Real-World Wound Care8 Apr 2025
- 2025Med-R2: Perception and Reflection-driven Complex Reasoning for Medical Report Generation2 Apr 2025
- 2025Shape Modeling of Longitudinal Medical Images: From Diffeomorphic Metric Mapping to Deep Learning27 Mar 2025
- 2025AutoRad-Lung: A Radiomic-Guided Prompting Autoregressive Vision-Language Model for Lung Nodule Malignancy Prediction26 Mar 2025
- 2025Collective Reasoning Among LLMs: A Framework for Answer Validation Without Ground Truth28 Feb 2025
- 2025GONet: A Generalizable Deep Learning Model for Glaucoma Detection26 Feb 2025
- 2025Medical Image Classification with KAN-Integrated Transformers and Dilated Neighborhood Attention19 Feb 2025
- 2025A Self-supervised Multimodal Deep Learning Approach to Differentiate Post-radiotherapy Progression from Pseudoprogression in Glioblastoma6 Feb 2025
- 2025Circuit Complexity Bounds for Visual Autoregressive Model8 Jan 2025
- 2024Advances in Transformers for Robotic Applications: A Review13 Dec 2024
- 2024Enhancing Answer Reliability Through Inter-Model Consensus of Large Language Models25 Nov 2024
- 2024Artificial Intelligence in Pediatric Echocardiography: Exploring Challenges, Opportunities, and Clinical Applications with Explainable AI and Federated Learning15 Nov 2024
- 2024Ultrasound-Based AI for COVID-19 Detection: A Comprehensive Review of Public and Private Lung Ultrasound Datasets and Studies6 Nov 2024
- 2024MedVisionLlama: Leveraging Pre-Trained Large Language Model Layers to Enhance Medical Image Segmentation3 Oct 2024
- 2024Tissue Concepts: supervised foundation models in computational pathology5 Sep 2024
- 2024Channel Boosted CNN-Transformer-based Multi-Level and Multi-Scale Nuclei Segmentation27 Jul 2024
- 2024Integrating Clinical Knowledge Graphs and Gradient-Based Neural Systems for Enhanced Melanoma Diagnosis via the 7-Point Checklist23 Jul 2024
- 2024Deep Learning for Pancreas Segmentation: a Systematic Review23 Jul 2024
- 2024xLSTM-UNet can be an Effective 2D & 3D Medical Image Segmentation Backbone with Vision-LSTM (ViL) better than its Mamba Counterpart1 Jul 2024
- 2024Multimodal Data Integration for Precision Oncology: Challenges and Future Directions28 Jun 2024
- 2024Multi-modality Regional Alignment Network for Covid X-Ray Survival Prediction and Report Generation23 May 2024
- 2024Comprehensive Multimodal Deep Learning Survival Prediction Enabled by a Transformer Architecture: A Multicenter Study in Glioblastoma21 May 2024
- 2024Key Patches Are All You Need: A Multiple Instance Learning Framework For Robust Medical Diagnosis2 May 2024
- 2024LHU-Net: a Lean Hybrid U-Net for Cost-efficient, High-performance Volumetric Segmentation7 Apr 2024
- 2024Enhancing Efficiency in Vision Transformer Networks: Design Techniques and Insights28 Mar 2024
- 2024SDR-Former: A Siamese Dual-Resolution Transformer for Liver Lesion Classification Using 3D Multi-Phase Imaging27 Feb 2024
- 2024Exploring the Synergies of Hybrid CNNs and ViTs Architectures for Computer Vision: A survey5 Feb 2024
- 2024Evaluating LLM -- Generated Multimodal Diagnosis from Medical Images and Symptom Analysis28 Jan 2024
- 2024Deep Spatiotemporal Clutter Filtering of Transthoracic Echocardiographic Images: Leveraging Contextual Attention and Residual Learning23 Jan 2024
50 newest of 62 All 62 (JSON)
- 2023Implicit Neural Representation in Medical Imaging: A Comparative Surveycited by 88
- 2023Foundational Models in Medical Imaging: A Comprehensive Survey and Future Visioncited by 74
- 2023Loss Functions in the Era of Semantic Segmentation: A Survey and Outlookcited by 33
- 2023Beyond Self-Attention: Deformable Large Kernel Attention for Medical Image Segmentationcited by 30
- 2024Evaluating LLM -- Generated Multimodal Diagnosis from Medical Images and Symptom Analysiscited by 23
- 2023A Recent Survey of Vision Transformers for Medical Image Segmentationcited by 22
- 2023Continual Learning in Medical Image Analysis: A Comprehensive Review of Recent Advancements and Future Prospectscited by 22
- 2024SDR-Former: A Siamese Dual-Resolution Transformer for Liver Lesion Classification Using 3D Multi-Phase Imagingcited by 17
- 2024Exploring the Synergies of Hybrid CNNs and ViTs Architectures for Computer Vision: A surveycited by 13
- 2023Enhancing Medical Image Segmentation with TransCeption: A Multi-Scale Feature Fusion Approachcited by 11
- 2024Multimodal Data Integration for Precision Oncology: Challenges and Future Directionscited by 10
- 2025Circuit Complexity Bounds for Visual Autoregressive Modelcited by 10
12 most cited of 54 All 54 (JSON)
- 2026Beyond Classification: Structured Supervision Aligns Visual Evidence with Medical Semantics5 Sep 2026
- 2026Vision Foundation Models in Radiology: A Scoping Review of Data, Methodology, Evaluation and Clinical Translation8 Jul 2026
- 2026Attention-Guided Fusion of 1D and 2D CNNs for Robust ECG-Based Biometric Recognition17 May 2026
- 2026Multi-Dataset Cross-Domain Knowledge Distillation for Unified Medical Image Segmentation, Classification, and Detection2 May 2026
- 2026Towards interpretable AI with quantum annealing feature selection28 Apr 2026
- 2026Interpretable Prostate Cancer Detection using a Small Cohort of MRI Images19 Mar 2026
- 2026Meningioma Analysis and Diagnosis using Limited Labeled Samples11 Feb 2026
- 2025Skin Cancer Classification: Hybrid CNN-Transformer Models with KAN-Based Fusion17 Aug 2025
- 2025TCSAFormer: Efficient Vision Transformer with Token Compression and Sparse Attention for Medical Image Segmentation6 Aug 2025
- 2025Structured Spectral Graph Learning for Anomaly Classification in 3D Chest CT Scans1 Aug 2025
- 2025SwinECAT: A Transformer-based fundus disease classification model with Shifted Window Attention and Efficient Channel Attention29 Jul 2025
- 2025Enhancing Breast Cancer Detection with Vision Transformers and Graph Neural Networks11 Jul 2025
12 newest of 54 All 54 (JSON)