A sequence-to-sequence approach for document-level relation extraction
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Abstract (arXiv)
Motivated by the fact that many relations cross the sentence boundary, there has been increasing interest in document-level relation extraction (DocRE). DocRE requires integrating information within and across sentences, capturing complex interactions between mentions of entities. Most existing methods are pipeline-based, requiring entities as input. However, jointly learning to extract entities and relations can improve performance and be more efficient due to shared parameters and training steps. In this paper, we develop a sequence-to-sequence approach, seq2rel, that can learn the subtasks of DocRE (entity extraction, coreference resolution and relation extraction) end-to-end, replacing a pipeline of task-specific components. Using a simple strategy we call entity hinting, we compare our approach to existing pipeline-based methods on several popular biomedical datasets, in some cases exceeding their performance. We also report the first end-to-end results on these datasets for future comparison. Finally, we demonstrate that, under our model, an end-to-end approach outperforms a pipeline-based approach. Our code, data and trained models are available at urlhttps://github.com/johngiorgi/seq2rel. An online demo is available at urlhttps://share.streamlit.io/johngiorgi/seq2rel/main/demo.py.
Key facts. Cited by 25 papers in the map (data through 14 Oct 2026). Builds on 41 of its 81 references that are in the map. First posted on arXiv 3 Apr 2022.
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Citing papers per year: 2022: 5; 2023: 8; 2024: 9; 2025: 3.
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- 2023Document-Level In-Context Few-Shot Relation Extraction via Pre-Trained Language Models17 Oct 2023
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- 2023FactReranker: Fact-guided Reranker for Faithful Radiology Report Summarization15 Mar 2023
- 2022Structured information extraction from complex scientific text with fine-tuned large language models10 Dec 2022
- 2022DORE: Document Ordered Relation Extraction based on Generative Framework28 Oct 2022
- 2022Generative Knowledge Graph Construction: A Review23 Oct 2022
- 2022BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Mining19 Oct 2022
- 2022Joint Learning-based Causal Relation Extraction from Biomedical Literature2 Aug 2022
- 2022BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Miningcited by 538
- 2022Structured information extraction from complex scientific text with fine-tuned large language modelscited by 56
- 2022Generative Knowledge Graph Construction: A Reviewcited by 49
- 2024Consistency Guided Knowledge Retrieval and Denoising in LLMs for Zero-shot Document-level Relation Triplet Extractioncited by 14
- 2023Beyond Rule-based Named Entity Recognition and Relation Extraction for Process Model Generation from Natural Language Textcited by 8
- 2023FactReranker: Fact-guided Reranker for Faithful Radiology Report Summarizationcited by 6
- 2024An Autoregressive Text-to-Graph Framework for Joint Entity and Relation Extractioncited by 5
- 2023Rethinking Document-Level Relation Extraction: A Reality Checkcited by 4
- 2024Empirical Analysis of Dialogue Relation Extraction with Large Language Modelscited by 4
- 2022DORE: Document Ordered Relation Extraction based on Generative Frameworkcited by 3
- 2023End-to-End n-ary Relation Extraction for Combination Drug Therapiescited by 3
- 2023Document-Level In-Context Few-Shot Relation Extraction via Pre-Trained Language Modelscited by 2
12 most cited of 24 All 24 (JSON)
- 2025ComProScanner: A multi-agent based framework for composition-property structured data extraction from scientific literature23 Oct 2025
- 2025Question-Answer Extraction from Scientific Articles Using Knowledge Graphs and Large Language Models18 Jul 2025
- 2025A Benchmark for End-to-End Zero-Shot Biomedical Relation Extraction with LLMs: Experiments with OpenAI Models5 Apr 2025
- 2024On the Robustness of Document-Level Relation Extraction Models to Entity Name Variations11 Jun 2024
- 2024Predicting drug-gene relations via analogy tasks with word embeddings3 Jun 2024
- 2024Empirical Analysis of Dialogue Relation Extraction with Large Language Models27 Apr 2024
- 2024Automated Text Mining of Experimental Methodologies from Biomedical Literature21 Apr 2024
- 2024Extracting Polymer Nanocomposite Samples from Full-Length Documents1 Mar 2024
- 2024How Important is Domain Specificity in Language Models and Instruction Finetuning for Biomedical Relation Extraction?21 Feb 2024
- 2024Consistency Guided Knowledge Retrieval and Denoising in LLMs for Zero-shot Document-level Relation Triplet Extraction24 Jan 2024
- 2024Chem-FINESE: Validating Fine-Grained Few-shot Entity Extraction through Text Reconstruction18 Jan 2024
- 2024An Autoregressive Text-to-Graph Framework for Joint Entity and Relation Extraction2 Jan 2024
12 newest of 24 All 24 (JSON)