Model Agnostic Interpretability for Multiple Instance Learning
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Abstract (arXiv)
In Multiple Instance Learning (MIL), models are trained using bags of instances, where only a single label is provided for each bag. A bag label is often only determined by a handful of key instances within a bag, making it difficult to interpret what information a classifier is using to make decisions. In this work, we establish the key requirements for interpreting MIL models. We then go on to develop several model-agnostic approaches that meet these requirements. Our methods are compared against existing inherently interpretable MIL models on several datasets, and achieve an increase in interpretability accuracy of up to 30%. We also examine the ability of the methods to identify interactions between instances and scale to larger datasets, improving their applicability to real-world problems.
Key facts. Cited by 10 papers in the map (data through 7 Oct 2026). Builds on 12 of its 30 references that are in the map. First posted on arXiv 27 Jan 2022.
Builds on
12 of 30 references.
References · 12
- 2017A Unified Approach to Interpreting Model Predictionscited by 6,488
- 2016"Why Should I Trust You?": Explaining the Predictions of Any Classifiercited by 5,040
- 2018Attention-based Deep Multiple Instance Learningcited by 1,077
- 2018Explaining Explanations: An Overview of Interpretability of Machine Learningcited by 508
- 2015Evaluating the visualization of what a Deep Neural Network has learnedcited by 416
- 2016Model-Agnostic Interpretability of Machine Learningcited by 219
- 2016Multiple Instance Learning: A Survey of Problem Characteristics and Applicationscited by 163
- 2020Improving KernelSHAP: Practical Shapley Value Estimation via Linear Regressioncited by 153
- 2016Revisiting Multiple Instance Neural Networkscited by 119
- 2019Multiple instance learning with graph neural networkscited by 25
- 2018Learning and Interpreting Multi-Multi-Instance Learning Networkscited by 9
- 2021Nested Multiple Instance Learning with Attention Mechanismscited by 7
Built on by
Citing papers per year: 2022: 2; 2023: 1; 2024: 4; 2025: 0; 2026: 3.
10 papers.
- 2024Explainable and Interpretable Multimodal Large Language Models: A Comprehensive Surveycited by 52
- 2023Inherently Interpretable Time Series Classification via Multiple Instance Learningcited by 23
- 2024xMIL: Insightful Explanations for Multiple Instance Learning in Histopathologycited by 15
- 2022Non-Markovian Reward Modelling from Trajectory Labels via Interpretable Multiple Instance Learningcited by 13
- 2024Multiple Instance Verificationcited by 2
- 2026Beyond Attention Heatmaps: How to Get Better Explanations for Multiple Instance Learning Models in Histopathologycited by 2
- 2022Scene-to-Patch Earth Observation: Multiple Instance Learning for Land Cover Classificationcited by 1
- 2024Explaining Black-box Model Predictions via Two-level Nested Feature Attributions with Consistency Propertycited by 0
- 2026Symb-xMIL: Symbolic Explanations for Multiple Instance Learning in Digital Pathologycited by 0
- 2026CAR-MIL: Counterfactual Attention Regularization for Multiple Instance Learningcited by 0
- 2026CAR-MIL: Counterfactual Attention Regularization for Multiple Instance Learning8 Sep 2026
- 2026Symb-xMIL: Symbolic Explanations for Multiple Instance Learning in Digital Pathology4 Jun 2026
- 2026Beyond Attention Heatmaps: How to Get Better Explanations for Multiple Instance Learning Models in Histopathology9 Mar 2026
- 2024Explainable and Interpretable Multimodal Large Language Models: A Comprehensive Survey3 Dec 2024
- 2024Multiple Instance Verification9 Jul 2024
- 2024xMIL: Insightful Explanations for Multiple Instance Learning in Histopathology6 Jun 2024
- 2024Explaining Black-box Model Predictions via Two-level Nested Feature Attributions with Consistency Property23 May 2024
- 2023Inherently Interpretable Time Series Classification via Multiple Instance Learning16 Nov 2023
- 2022Scene-to-Patch Earth Observation: Multiple Instance Learning for Land Cover Classification15 Nov 2022
- 2022Non-Markovian Reward Modelling from Trajectory Labels via Interpretable Multiple Instance Learning30 May 2022