Trust Issues: Uncertainty Estimation Does Not Enable Reliable OOD Detection On Medical Tabular Data
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Abstract (arXiv)
When deploying machine learning models in high-stakes real-world environments such as health care, it is crucial to accurately assess the uncertainty concerning a model's prediction on abnormal inputs. However, there is a scarcity of literature analyzing this problem on medical data, especially on mixed-type tabular data such as Electronic Health Records. We close this gap by presenting a series of tests including a large variety of contemporary uncertainty estimation techniques, in order to determine whether they are able to identify out-of-distribution (OOD) patients. In contrast to previous work, we design tests on realistic and clinically relevant OOD groups, and run experiments on real-world medical data. We find that almost all techniques fail to achieve convincing results, partly disagreeing with earlier findings.
Key facts. Cited by 52 papers in the map (data through 7 Oct 2026). First posted on arXiv 6 Nov 2020.
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Citing papers per year: 2021: 6; 2022: 3; 2023: 14; 2024: 15; 2025: 9; 2026: 5.
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- 2021Deep Neural Networks and Tabular Data: A Surveycited by 489
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- 2023Constrained Adaptive Attacks: Realistic Evaluation of Adversarial Examples and Robust Training of Deep Neural Networks for Tabular Datacited by 1
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- 2025GLIP-OOD: Zero-Shot Graph OOD Detection with Graph Foundation Modelcited by 1
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50 most cited of 52 All 52 (JSON)
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- 2026FORESTLLM: Large Language Models Make Random Forest Great on Few-shot Tabular Learning16 Jan 2026
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- 2025MultiTab: A Comprehensive Benchmark Suite for Multi-Dimensional Evaluation in Tabular Domains20 May 2025
- 2025GLIP-OOD: Zero-Shot Graph OOD Detection with Graph Foundation Model29 Apr 2025
- 2025How to RETIRE Tabular Data in Favor of Discrete Digital Signal Representation25 Mar 2025
38 more
- 2025Prior-Fitted Networks Scale to Larger Datasets When Treated as Weak Learners3 Mar 2025
- 2025Outlier Synthesis via Hamiltonian Monte Carlo for Out-of-Distribution Detection28 Jan 2025
- 2024Understanding and Mitigating Memorization in Diffusion Models for Tabular Data15 Dec 2024
- 2024A Neural Network Alternative to Tree-based Models23 Oct 2024
- 2024MetaOOD: Automatic Selection of OOD Detection Models4 Oct 2024
- 2024TabKANet: Tabular Data Modeling with Kolmogorov-Arnold Network and Transformer13 Sep 2024
- 2024TabularBench: Benchmarking Adversarial Robustness for Tabular Deep Learning in Real-world Use-cases14 Aug 2024
- 2024Tabular Transfer Learning via Prompting LLMs9 Aug 2024
- 2024TabPFGen -- Tabular Data Generation with TabPFN7 Jun 2024
- 2024Retrieval & Fine-Tuning for In-Context Tabular Models7 Jun 2024
- 2024Constrained Adaptive Attack: Effective Adversarial Attack Against Deep Neural Networks for Tabular Data2 Jun 2024
- 2024Mitigating Overconfidence in Out-of-Distribution Detection by Capturing Extreme Activations21 May 2024
- 2024VI-OOD: A Unified Representation Learning Framework for Textual Out-of-distribution Detection9 Apr 2024
- 2024Calibrating Large Language Models Using Their Generations Only9 Mar 2024
- 2024Approximations to the Fisher Information Metric of Deep Generative Models for Out-Of-Distribution Detection3 Mar 2024
- 2024TuneTables: Context Optimization for Scalable Prior-Data Fitted Networks17 Feb 2024
- 2024How Useful is Continued Pre-Training for Generative Unsupervised Domain Adaptation?31 Jan 2024
- 2023Constrained Adaptive Attacks: Realistic Evaluation of Adversarial Examples and Robust Training of Deep Neural Networks for Tabular Data8 Nov 2023
- 2023Distribution-free risk assessment of regression-based machine learning algorithms5 Oct 2023
- 2023Can Pre-trained Networks Detect Familiar Out-of-Distribution Data?2 Oct 2023
- 2023GRANDE: Gradient-Based Decision Tree Ensembles for Tabular Data29 Sep 2023
- 2023Unmasking the Chameleons: A Benchmark for Out-of-Distribution Detection in Medical Tabular Data28 Sep 2023
- 2023Generating tabular datasets under differential privacy28 Aug 2023
- 2023Homological Convolutional Neural Networks26 Aug 2023
- 2023Generating with Confidence: Uncertainty Quantification for Black-box Large Language Models30 May 2023
- 2023Is Fine-tuning Needed? Pre-trained Language Models Are Near Perfect for Out-of-Domain Detection22 May 2023
- 2023When Do Neural Nets Outperform Boosted Trees on Tabular Data?4 May 2023
- 2023MLHOps: Machine Learning for Healthcare Operations4 May 2023
- 2023Deep Anti-Regularized Ensembles provide reliable out-of-distribution uncertainty quantification8 Apr 2023
- 2023STUNT: Few-shot Tabular Learning with Self-generated Tasks from Unlabeled Tables2 Mar 2023
- 2023TT-TFHE: a Torus Fully Homomorphic Encryption-Friendly Neural Network Architecture3 Feb 2023
- 2022Exploring Predictive Uncertainty and Calibration in NLP: A Study on the Impact of Method & Data Scarcity20 Oct 2022
- 2022JAWS: Auditing Predictive Uncertainty Under Covariate Shift21 Jul 2022
- 2022Simple Calibration via Geodesic Kernels31 Jan 2022
- 2021Benchmarking Uncertainty Quantification on Biosignal Classification Tasks under Dataset Shift16 Dec 2021
- 2021Bi-Discriminator Class-Conditional Tabular GAN12 Nov 2021
- 2021Prior and Posterior Networks: A Survey on Evidential Deep Learning Methods For Uncertainty Estimation6 Oct 2021
- 2021Deep Neural Networks and Tabular Data: A Survey5 Oct 2021
50 newest of 52 All 52 (JSON)
- 2021Deep Neural Networks and Tabular Data: A Surveycited by 489
- 2023Generating with Confidence: Uncertainty Quantification for Black-box Large Language Modelscited by 286
- 2023When Do Neural Nets Outperform Boosted Trees on Tabular Data?cited by 218
- 2021Prior and Posterior Networks: A Survey on Evidential Deep Learning Methods For Uncertainty Estimationcited by 71
- 2024Calibrating Large Language Models Using Their Generations Onlycited by 63
- 2024Retrieval & Fine-Tuning for In-Context Tabular Modelscited by 58
- 2023STUNT: Few-shot Tabular Learning with Self-generated Tasks from Unlabeled Tablescited by 48
- 2024TuneTables: Context Optimization for Scalable Prior-Data Fitted Networkscited by 47
- 2023Is Fine-tuning Needed? Pre-trained Language Models Are Near Perfect for Out-of-Domain Detectioncited by 29
- 2024TabPFGen -- Tabular Data Generation with TabPFNcited by 26
- 2022Exploring Predictive Uncertainty and Calibration in NLP: A Study on the Impact of Method & Data Scarcitycited by 24
- 2024MetaOOD: Automatic Selection of OOD Detection Modelscited by 16
12 most cited of 50 All 50 (JSON)
- 2026CITBench: A Comprehensive Benchmark for Interactive Tabular Data Processing with LLMs29 Jun 2026
- 2026RelPrism: A Multi-Faceted Pre-training Framework with Self-Generated Tasks for Relational Databases22 May 2026
- 2026Rethinking external validation for the target population: Capturing patient-level similarity with a generative model11 May 2026
- 2026An Isotropic Approach to Efficient Uncertainty Quantification with Gradient Norms31 Mar 2026
- 2026FORESTLLM: Large Language Models Make Random Forest Great on Few-shot Tabular Learning16 Jan 2026
- 2025CatBack: Universal Backdoor Attacks on Tabular Data via Categorical Encoding8 Nov 2025
- 2025M3OOD: Automatic Selection of Multimodal OOD Detectors16 Aug 2025
- 2025LLM Empowered Prototype Learning for Zero and Few-Shot Tasks on Tabular Data12 Aug 2025
- 2025Doubling Your Data in Minutes: Ultra-fast Tabular Data Generation via LLM-Induced Dependency Graphs25 Jul 2025
- 2025MultiTab: A Comprehensive Benchmark Suite for Multi-Dimensional Evaluation in Tabular Domains20 May 2025
- 2025GLIP-OOD: Zero-Shot Graph OOD Detection with Graph Foundation Model29 Apr 2025
- 2025How to RETIRE Tabular Data in Favor of Discrete Digital Signal Representation25 Mar 2025
12 newest of 50 All 50 (JSON)