What is Wrong with Continual Learning in Medical Image Segmentation?
Not on the map. Why?
Abstract (arXiv)
Continual learning protocols are attracting increasing attention from the medical imaging community. In continual environments, datasets acquired under different conditions arrive sequentially; and each is only available for a limited period of time. Given the inherent privacy risks associated with medical data, this setup reflects the reality of deployment for deep learning diagnostic radiology systems. Many techniques exist to learn continuously for image classification, and several have been adapted to semantic segmentation. Yet most struggle to accumulate knowledge in a meaningful manner. Instead, they focus on preventing the problem of catastrophic forgetting, even when this reduces model plasticity and thereon burdens the training process. This puts into question whether the additional overhead of knowledge preservation is worth it - particularly for medical image segmentation, where computation requirements are already high - or if maintaining separate models would be a better solution. We propose UNEG, a simple and widely applicable multi-model benchmark that maintains separate segmentation and autoencoder networks for each training stage. The autoencoder is built from the same architecture as the segmentation network, which in our case is a full-resolution nnU-Net, to bypass any additional design decisions. During inference, the reconstruction error is used to select the most appropriate segmenter for each test image. Open this concept, we develop a fair evaluation scheme for different continual learning settings that moves beyond the prevention of catastrophic forgetting. Our results across three regions of interest (prostate, hippocampus, and right ventricle) show that UNEG outperforms several continual learning methods, reinforcing the need for strong baselines in continual learning research.
Key facts. Cited by 25 papers in the map (data through 7 Oct 2026). First posted on arXiv 21 Oct 2020.
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Citing papers per year: 2021: 4; 2022: 3; 2023: 7; 2024: 8; 2025: 1; 2026: 2.
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- 2022LifeLonger: A Benchmark for Continual Disease Classificationcited by 28
- 2023Continual Learning in Medical Image Analysis: A Comprehensive Review of Recent Advancements and Future Prospectscited by 22
- 2023A Survey on Continual Semantic Segmentation: Theory, Challenge, Method and Applicationcited by 21
- 2023Rethinking Exemplars for Continual Semantic Segmentation in Endoscopy Scenes: Entropy-based Mini-Batch Pseudo-Replaycited by 20
- 2022Domain-incremental Cardiac Image Segmentation with Style-oriented Replay and Domain-sensitive Feature Whiteningcited by 16
- 2021Adversarial Continual Learning for Multi-Domain Hippocampal Segmentationcited by 14
- 2022Continual Hippocampus Segmentation with Transformerscited by 11
- 2021Continual Active Learning for Efficient Adaptation of Machine Learning Models to Changing Image Acquisitioncited by 9
- 2024Continual Learning in Medical Imaging: A Survey and Practical Analysiscited by 9
- 2023Generative appearance replay for continual unsupervised domain adaptationcited by 8
- 2024Controllable Continual Test-Time Adaptationcited by 6
- 2021Bristle: Decentralized Federated Learning in Byzantine, Non-i.i.d. Environmentscited by 4
13 more
- 2024Is Continual Learning Ready for Real-world Challenges?cited by 4
- 2021Continual Active Learning Using Pseudo-Domains for Limited Labelling Resources and Changing Acquisition Characteristicscited by 3
- 2024Memory-Efficient Prompt Tuning for Incremental Histopathology Classificationcited by 3
- 2024Distribution-Aware Replay for Continual MRI Segmentationcited by 3
- 2024Fairness Evolution in Continual Learning for Medical Imagingcited by 2
- 2024NCAdapt: Dynamic adaptation with domain-specific Neural Cellular Automata for continual hippocampus segmentationcited by 2
- 2025Decoupling Continual Semantic Segmentationcited by 2
- 2023TADIL: Task-Agnostic Domain-Incremental Learning through Task-ID Inference using Transformer Nearest-Centroid Embeddingscited by 1
- 2023A dynamic interactive learning framework for automated 3D medical image segmentationcited by 1
- 2023Exploring UMAP in hybrid models of entropy-based and representativeness sampling for active learning in biomedical segmentationcited by 1
- 2024From Lab to Pocket: A Novel Continual Learning-based Mobile Application for Screening COVID-19cited by 0
- 2026Beyond Forgetting in Continual Medical Image Segmentation: A Comprehensive Benchmark Studycited by 0
- 2026What to Preserve, Where to Adapt: A Depth-Wise Analysis of Forgetting in Continual Gynecological Image Segmentationcited by 0
- 2026What to Preserve, Where to Adapt: A Depth-Wise Analysis of Forgetting in Continual Gynecological Image Segmentation13 Aug 2026
- 2026Beyond Forgetting in Continual Medical Image Segmentation: A Comprehensive Benchmark Study7 May 2026
- 2025Decoupling Continual Semantic Segmentation7 Aug 2025
- 2024NCAdapt: Dynamic adaptation with domain-specific Neural Cellular Automata for continual hippocampus segmentation30 Oct 2024
- 2024From Lab to Pocket: A Novel Continual Learning-based Mobile Application for Screening COVID-1916 Oct 2024
- 2024Distribution-Aware Replay for Continual MRI Segmentation30 Jul 2024
- 2024Controllable Continual Test-Time Adaptation23 May 2024
- 2024Continual Learning in Medical Imaging: A Survey and Practical Analysis22 May 2024
- 2024Fairness Evolution in Continual Learning for Medical Imaging10 Apr 2024
- 2024Is Continual Learning Ready for Real-world Challenges?15 Feb 2024
- 2024Memory-Efficient Prompt Tuning for Incremental Histopathology Classification22 Jan 2024
- 2023Continual Learning in Medical Image Analysis: A Comprehensive Review of Recent Advancements and Future Prospects28 Dec 2023
13 more
- 2023Exploring UMAP in hybrid models of entropy-based and representativeness sampling for active learning in biomedical segmentation16 Dec 2023
- 2023A dynamic interactive learning framework for automated 3D medical image segmentation11 Dec 2023
- 2023A Survey on Continual Semantic Segmentation: Theory, Challenge, Method and Application22 Oct 2023
- 2023Rethinking Exemplars for Continual Semantic Segmentation in Endoscopy Scenes: Entropy-based Mini-Batch Pseudo-Replay27 Aug 2023
- 2023TADIL: Task-Agnostic Domain-Incremental Learning through Task-ID Inference using Transformer Nearest-Centroid Embeddings21 Jun 2023
- 2023Generative appearance replay for continual unsupervised domain adaptation3 Jan 2023
- 2022Domain-incremental Cardiac Image Segmentation with Style-oriented Replay and Domain-sensitive Feature Whitening9 Nov 2022
- 2022Continual Hippocampus Segmentation with Transformers17 Apr 2022
- 2022LifeLonger: A Benchmark for Continual Disease Classification12 Apr 2022
- 2021Continual Active Learning Using Pseudo-Domains for Limited Labelling Resources and Changing Acquisition Characteristics25 Nov 2021
- 2021Bristle: Decentralized Federated Learning in Byzantine, Non-i.i.d. Environments21 Oct 2021
- 2021Adversarial Continual Learning for Multi-Domain Hippocampal Segmentation19 Jul 2021
- 2021Continual Active Learning for Efficient Adaptation of Machine Learning Models to Changing Image Acquisition7 Jun 2021
- 2022LifeLonger: A Benchmark for Continual Disease Classificationcited by 28
- 2023Continual Learning in Medical Image Analysis: A Comprehensive Review of Recent Advancements and Future Prospectscited by 22
- 2023A Survey on Continual Semantic Segmentation: Theory, Challenge, Method and Applicationcited by 21
- 2023Rethinking Exemplars for Continual Semantic Segmentation in Endoscopy Scenes: Entropy-based Mini-Batch Pseudo-Replaycited by 20
- 2022Domain-incremental Cardiac Image Segmentation with Style-oriented Replay and Domain-sensitive Feature Whiteningcited by 16
- 2021Adversarial Continual Learning for Multi-Domain Hippocampal Segmentationcited by 14
- 2022Continual Hippocampus Segmentation with Transformerscited by 11
- 2021Continual Active Learning for Efficient Adaptation of Machine Learning Models to Changing Image Acquisitioncited by 9
- 2024Continual Learning in Medical Imaging: A Survey and Practical Analysiscited by 9
- 2023Generative appearance replay for continual unsupervised domain adaptationcited by 8
- 2024Controllable Continual Test-Time Adaptationcited by 6
- 2021Bristle: Decentralized Federated Learning in Byzantine, Non-i.i.d. Environmentscited by 4
12 most cited of 25 All 25 (JSON)
- 2026What to Preserve, Where to Adapt: A Depth-Wise Analysis of Forgetting in Continual Gynecological Image Segmentation13 Aug 2026
- 2026Beyond Forgetting in Continual Medical Image Segmentation: A Comprehensive Benchmark Study7 May 2026
- 2025Decoupling Continual Semantic Segmentation7 Aug 2025
- 2024NCAdapt: Dynamic adaptation with domain-specific Neural Cellular Automata for continual hippocampus segmentation30 Oct 2024
- 2024From Lab to Pocket: A Novel Continual Learning-based Mobile Application for Screening COVID-1916 Oct 2024
- 2024Distribution-Aware Replay for Continual MRI Segmentation30 Jul 2024
- 2024Controllable Continual Test-Time Adaptation23 May 2024
- 2024Continual Learning in Medical Imaging: A Survey and Practical Analysis22 May 2024
- 2024Fairness Evolution in Continual Learning for Medical Imaging10 Apr 2024
- 2024Is Continual Learning Ready for Real-world Challenges?15 Feb 2024
- 2024Memory-Efficient Prompt Tuning for Incremental Histopathology Classification22 Jan 2024
- 2023Continual Learning in Medical Image Analysis: A Comprehensive Review of Recent Advancements and Future Prospects28 Dec 2023
12 newest of 25 All 25 (JSON)