Neural Temporal Point Processes For Modelling Electronic Health Records
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Abstract (arXiv)
The modelling of Electronic Health Records (EHRs) has the potential to drive more efficient allocation of healthcare resources, enabling early intervention strategies and advancing personalised healthcare. However, EHRs are challenging to model due to their realisation as noisy, multi-modal data occurring at irregular time intervals. To address their temporal nature, we treat EHRs as samples generated by a Temporal Point Process (TPP), enabling us to model what happened in an event with when it happened in a principled way. We gather and propose neural network parameterisations of TPPs, collectively referred to as Neural TPPs. We perform evaluations on synthetic EHRs as well as on a set of established benchmarks. We show that TPPs significantly outperform their non-TPP counterparts on EHRs. We also show that an assumption of many Neural TPPs, that the class distribution is conditionally independent of time, reduces performance on EHRs. Finally, our proposed attention-based Neural TPP performs favourably compared to existing models, whilst aligning with real world interpretability requirements, an important step towards a component of clinical decision support systems.
Key facts. Cited by 39 papers in the map (data through 7 Oct 2026). First posted on arXiv 27 Jul 2020.
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Citing papers per year: 2021: 4; 2022: 5; 2023: 9; 2024: 10; 2025: 6; 2026: 5.
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- 2021Neural Temporal Point Processes: A Reviewcited by 113
- 2021Transformer Embeddings of Irregularly Spaced Events and Their Participantscited by 90
- 2022HYPRO: A Hybridly Normalized Probabilistic Model for Long-Horizon Prediction of Event Sequencescited by 57
- 2023Event Stream GPT: A Data Pre-processing and Modeling Library for Generative, Pre-trained Transformers over Continuous-time Sequences of Complex Eventscited by 46
- 2023Language Models Can Improve Event Prediction by Few-Shot Abductive Reasoningcited by 44
- 2023Anticipatory Music Transformercited by 35
- 2023Add and Thin: Diffusion for Temporal Point Processescited by 22
- 2022Cardinality-Regularized Hawkes-Granger Modelcited by 14
- 2023On the Predictive Accuracy of Neural Temporal Point Process Models for Continuous-time Event Datacited by 13
- 2023Spatio-Temporal Graph Neural Point Process for Traffic Congestion Event Predictioncited by 13
- 2021An Empirical Study: Extensive Deep Temporal Point Processcited by 10
- 2022Modeling Inter-Dependence Between Time and Mark in Multivariate Temporal Point Processescited by 7
27 more
- 2024Distribution-Free Conformal Joint Prediction Regions for Neural Marked Temporal Point Processescited by 7
- 2025Edit-Based Flow Matching for Temporal Point Processescited by 7
- 2021Detecting Anomalous Event Sequences with Temporal Point Processescited by 6
- 2022Probabilistic Querying of Continuous-Time Event Sequencescited by 5
- 2026One Loss to Rule Them All: Marked Time-to-Event for Structured EHR Foundation Modelscited by 5
- 2024TPP-Gaze: Modelling Gaze Dynamics in Space and Time with Neural Temporal Point Processescited by 4
- 2024TEE4EHR: Transformer Event Encoder for Better Representation Learning in Electronic Health Recordscited by 3
- 2024Federated Neural Nonparametric Point Processescited by 3
- 2023Proactive Resource Request for Disaster Response: A Deep Learning-based Optimization Modelcited by 2
- 2024Interpretable Neural Temporal Point Processes for Modelling Electronic Health Recordscited by 2
- 2024On Non-asymptotic Theory of Recurrent Neural Networks in Temporal Point Processescited by 2
- 2024Detecting Abnormal Operations in Concentrated Solar Power Plants from Irregular Sequences of Thermal Imagescited by 2
- 2023Hawkes Process Based on Controlled Differential Equationscited by 1
- 2025Deep spatio-temporal point processes: Advances and new directionscited by 1
- 2022Challenges and opportunities in applying Neural Temporal Point Processes to large scale industry datacited by 0
- 2023Intensity-free Integral-based Learning of Marked Temporal Point Processescited by 0
- 2024On the Efficient Marginalization of Probabilistic Sequence Modelscited by 0
- 2024Marked Temporal Bayesian Flow Point Processescited by 0
- 2024Preventing Conflicting Gradients in Neural Marked Temporal Point Processescited by 0
- 2025Towards Unified Approaches in Self-Supervised Event Stream Modeling: Progress and Prospectscited by 0
- 2025Learning Marked Temporal Point Process Explanations based on Counterfactual and Factual Reasoningcited by 0
- 2025On Foundation Models for Temporal Point Processes to Accelerate Scientific Discoverycited by 0
- 2025Addressing Mark Imbalance in Integration-free Neural Marked Temporal Point Processescited by 0
- 2026Patient foundation model for risk stratification in low-risk overweight patientscited by 0
- 2026Latent Block-Diffusion Temporal Point Processes: A Semi-Autoregressive Framework for Asynchronous Event Sequence Generationcited by 0
- 2026ReDiTT: Retrieval Augmented Conditional Diffusion Transformers for Asynchronous Time Seriescited by 0
- 2026AdaPCLA: Adaptive Prior-Calibrated Logit Adjustment for Long-Tailed Longitudinal EHR Generationcited by 0
- 2026AdaPCLA: Adaptive Prior-Calibrated Logit Adjustment for Long-Tailed Longitudinal EHR Generation14 Jul 2026
- 2026ReDiTT: Retrieval Augmented Conditional Diffusion Transformers for Asynchronous Time Series14 Jul 2026
- 2026Latent Block-Diffusion Temporal Point Processes: A Semi-Autoregressive Framework for Asynchronous Event Sequence Generation23 Jun 2026
- 2026Patient foundation model for risk stratification in low-risk overweight patients9 Feb 2026
- 2026One Loss to Rule Them All: Marked Time-to-Event for Structured EHR Foundation Models31 Jan 2026
- 2025Addressing Mark Imbalance in Integration-free Neural Marked Temporal Point Processes23 Oct 2025
- 2025On Foundation Models for Temporal Point Processes to Accelerate Scientific Discovery14 Oct 2025
- 2025Edit-Based Flow Matching for Temporal Point Processes7 Oct 2025
- 2025Learning Marked Temporal Point Process Explanations based on Counterfactual and Factual Reasoning16 Aug 2025
- 2025Deep spatio-temporal point processes: Advances and new directions8 Apr 2025
- 2025Towards Unified Approaches in Self-Supervised Event Stream Modeling: Progress and Prospects7 Feb 2025
- 2024Preventing Conflicting Gradients in Neural Marked Temporal Point Processes11 Dec 2024
27 more
- 2024TPP-Gaze: Modelling Gaze Dynamics in Space and Time with Neural Temporal Point Processes30 Oct 2024
- 2024Marked Temporal Bayesian Flow Point Processes25 Oct 2024
- 2024Federated Neural Nonparametric Point Processes8 Oct 2024
- 2024Detecting Abnormal Operations in Concentrated Solar Power Plants from Irregular Sequences of Thermal Images23 Jun 2024
- 2024On Non-asymptotic Theory of Recurrent Neural Networks in Temporal Point Processes2 Jun 2024
- 2024Interpretable Neural Temporal Point Processes for Modelling Electronic Health Records9 Apr 2024
- 2024On the Efficient Marginalization of Probabilistic Sequence Models6 Mar 2024
- 2024TEE4EHR: Transformer Event Encoder for Better Representation Learning in Electronic Health Records9 Feb 2024
- 2024Distribution-Free Conformal Joint Prediction Regions for Neural Marked Temporal Point Processes9 Jan 2024
- 2023Spatio-Temporal Graph Neural Point Process for Traffic Congestion Event Prediction15 Nov 2023
- 2023Add and Thin: Diffusion for Temporal Point Processes2 Nov 2023
- 2023Intensity-free Integral-based Learning of Marked Temporal Point Processes4 Aug 2023
- 2023Proactive Resource Request for Disaster Response: A Deep Learning-based Optimization Model31 Jul 2023
- 2023On the Predictive Accuracy of Neural Temporal Point Process Models for Continuous-time Event Data29 Jun 2023
- 2023Event Stream GPT: A Data Pre-processing and Modeling Library for Generative, Pre-trained Transformers over Continuous-time Sequences of Complex Events20 Jun 2023
- 2023Anticipatory Music Transformer14 Jun 2023
- 2023Language Models Can Improve Event Prediction by Few-Shot Abductive Reasoning26 May 2023
- 2023Hawkes Process Based on Controlled Differential Equations9 May 2023
- 2022Probabilistic Querying of Continuous-Time Event Sequences15 Nov 2022
- 2022Modeling Inter-Dependence Between Time and Mark in Multivariate Temporal Point Processes27 Oct 2022
- 2022HYPRO: A Hybridly Normalized Probabilistic Model for Long-Horizon Prediction of Event Sequences4 Oct 2022
- 2022Cardinality-Regularized Hawkes-Granger Model23 Aug 2022
- 2022Challenges and opportunities in applying Neural Temporal Point Processes to large scale industry data18 Aug 2022
- 2021Transformer Embeddings of Irregularly Spaced Events and Their Participants31 Dec 2021
- 2021An Empirical Study: Extensive Deep Temporal Point Process19 Oct 2021
- 2021Detecting Anomalous Event Sequences with Temporal Point Processes8 Jun 2021
- 2021Neural Temporal Point Processes: A Review8 Apr 2021
- 2025Edit-Based Flow Matching for Temporal Point Processescited by 7
- 2025Edit-Based Flow Matching for Temporal Point Processes7 Oct 2025
- 2021Neural Temporal Point Processes: A Reviewcited by 113
- 2021Transformer Embeddings of Irregularly Spaced Events and Their Participantscited by 90
- 2022HYPRO: A Hybridly Normalized Probabilistic Model for Long-Horizon Prediction of Event Sequencescited by 57
- 2023Event Stream GPT: A Data Pre-processing and Modeling Library for Generative, Pre-trained Transformers over Continuous-time Sequences of Complex Eventscited by 46
- 2023Anticipatory Music Transformercited by 35
- 2023Add and Thin: Diffusion for Temporal Point Processescited by 22
- 2022Cardinality-Regularized Hawkes-Granger Modelcited by 14
- 2023On the Predictive Accuracy of Neural Temporal Point Process Models for Continuous-time Event Datacited by 13
- 2023Spatio-Temporal Graph Neural Point Process for Traffic Congestion Event Predictioncited by 13
- 2021An Empirical Study: Extensive Deep Temporal Point Processcited by 10
- 2022Modeling Inter-Dependence Between Time and Mark in Multivariate Temporal Point Processescited by 7
- 2024Distribution-Free Conformal Joint Prediction Regions for Neural Marked Temporal Point Processescited by 7
12 most cited of 36 All 36 (JSON)
- 2026AdaPCLA: Adaptive Prior-Calibrated Logit Adjustment for Long-Tailed Longitudinal EHR Generation14 Jul 2026
- 2026Latent Block-Diffusion Temporal Point Processes: A Semi-Autoregressive Framework for Asynchronous Event Sequence Generation23 Jun 2026
- 2026Patient foundation model for risk stratification in low-risk overweight patients9 Feb 2026
- 2026One Loss to Rule Them All: Marked Time-to-Event for Structured EHR Foundation Models31 Jan 2026
- 2025Addressing Mark Imbalance in Integration-free Neural Marked Temporal Point Processes23 Oct 2025
- 2025On Foundation Models for Temporal Point Processes to Accelerate Scientific Discovery14 Oct 2025
- 2025Learning Marked Temporal Point Process Explanations based on Counterfactual and Factual Reasoning16 Aug 2025
- 2025Deep spatio-temporal point processes: Advances and new directions8 Apr 2025
- 2025Towards Unified Approaches in Self-Supervised Event Stream Modeling: Progress and Prospects7 Feb 2025
- 2024Preventing Conflicting Gradients in Neural Marked Temporal Point Processes11 Dec 2024
- 2024TPP-Gaze: Modelling Gaze Dynamics in Space and Time with Neural Temporal Point Processes30 Oct 2024
- 2024Marked Temporal Bayesian Flow Point Processes25 Oct 2024
12 newest of 36 All 36 (JSON)