mlsanityData to 7 Oct 2026

Self-Supervision with Superpixels: Training Few-shot Medical Image Segmentation without Annotation

arXiv 2007.09886 ↗First posted 20 Jul 2020cs.CVcited by 128

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Abstract (arXiv)

Few-shot semantic segmentation (FSS) has great potential for medical imaging applications. Most of the existing FSS techniques require abundant annotated semantic classes for training. However, these methods may not be applicable for medical images due to the lack of annotations. To address this problem we make several contributions: (1) A novel self-supervised FSS framework for medical images in order to eliminate the requirement for annotations during training. Additionally, superpixel-based pseudo-labels are generated to provide supervision; (2) An adaptive local prototype pooling module plugged into prototypical networks, to solve the common challenging foreground-background imbalance problem in medical image segmentation; (3) We demonstrate the general applicability of the proposed approach for medical images using three different tasks: abdominal organ segmentation for CT and MRI, as well as cardiac segmentation for MRI. Our results show that, for medical image segmentation, the proposed method outperforms conventional FSS methods which require manual annotations for training.

Key facts. Cited by 128 papers in the map (data through 7 Oct 2026). First posted on arXiv 20 Jul 2020.

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Citing papers per year: 2021: 25; 2022: 24; 2023: 24; 2024: 28; 2025: 14; 2026: 13.

128 papers.

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  1. 2024Medical SAM 2: Segment medical images as video via Segment Anything Model 2cited by 151
  2. 2021Causality-inspired Single-source Domain Generalization for Medical Image Segmentationcited by 118
  3. 2022Self-Support Few-Shot Semantic Segmentationcited by 96
  4. 2023UniverSeg: Universal Medical Image Segmentationcited by 90
  5. 2021Mining Latent Classes for Few-shot Segmentationcited by 69
  6. 2021Recurrent Mask Refinement for Few-Shot Medical Image Segmentationcited by 63
  7. 2021Learning Meta-class Memory for Few-Shot Semantic Segmentationcited by 56
  8. 2024A Comprehensive Survey of Foundation Models in Medicinecited by 56
  9. 2023Domain Generalization for Medical Image Analysis: A Reviewcited by 47
  10. 2022Rethinking Data Augmentation for Single-source Domain Generalization in Medical Image Segmentationcited by 44
  11. 2021Local contrastive loss with pseudo-label based self-training for semi-supervised medical image segmentationcited by 43
  12. 2022Anomaly Detection-Inspired Few-Shot Medical Image Segmentation Through Self-Supervision With Supervoxelscited by 42
38 more
  1. 2022Generating Representative Samples for Few-Shot Classificationcited by 39
  2. 2023One-Prompt to Segment All Medical Imagescited by 38
  3. 2023MedFMC: A Real-world Dataset and Benchmark For Foundation Model Adaptation in Medical Image Classificationcited by 38
  4. 2021Reference-guided Pseudo-Label Generation for Medical Semantic Segmentationcited by 33
  5. 2022Few-shot Medical Image Segmentation with Cycle-resemblance Attentioncited by 33
  6. 2021One-Shot Medical Landmark Detectioncited by 31
  7. 2023Few-Shot Medical Image Segmentation via a Region-enhanced Prototypical Transformercited by 28
  8. 2022Q-Net: Query-Informed Few-Shot Medical Image Segmentationcited by 24
  9. 2021Medical Image Segmentation with Limited Supervision: A Review of Deep Network Modelscited by 21
  10. 2022Warm Start Active Learning with Proxy Labels & Selection via Semi-Supervised Fine-Tuningcited by 21
  11. 2022Prompt Tuning for Parameter-efficient Medical Image Segmentationcited by 21
  12. 2023Learning Expressive Prompting With Residuals for Vision Transformerscited by 21
  13. 2023Generating Features with Increased Crop-related Diversity for Few-Shot Object Detectioncited by 21
  14. 2022FHIST: A Benchmark for Few-shot Classification of Histological Imagescited by 20
  15. 2024Retrieval-augmented Few-shot Medical Image Segmentation with Foundation Modelscited by 20
  16. 2021Hierarchical Self-Supervised Learning for Medical Image Segmentation Based on Multi-Domain Data Aggregationcited by 18
  17. 2023Self-Sampling Meta SAM: Enhancing Few-shot Medical Image Segmentation with Meta-Learningcited by 18
  18. 2021A Location-Sensitive Local Prototype Network for Few-Shot Medical Image Segmentationcited by 17
  19. 2021Which images to label for few-shot medical landmark detection?cited by 16
  20. 2021Meta-learning with implicit gradients in a few-shot setting for medical image segmentationcited by 15
  21. 2021Squeezing Backbone Feature Distributions to the Max for Efficient Few-Shot Learningcited by 14
  22. 2022Prototypical few-shot segmentation for cross-institution male pelvic structures with spatial registrationcited by 14
  23. 2024Prototype Correlation Matching and Class-Relation Reasoning for Few-Shot Medical Image Segmentationcited by 13
  24. 2023G2D: From Global to Dense Radiography Representation Learning via Vision-Language Pre-trainingcited by 12
  25. 2024ProtoSAM: One-Shot Medical Image Segmentation With Foundational Modelscited by 12
  26. 2021Separated Contrastive Learning for Organ-at-Risk and Gross-Tumor-Volume Segmentation with Limited Annotationcited by 11
  27. 2024DINOv2 based Self Supervised Learning For Few Shot Medical Image Segmentationcited by 11
  28. 2021Self-Supervised Generative Style Transfer for One-Shot Medical Image Segmentationcited by 10
  29. 2023A Review of Predictive and Contrastive Self-supervised Learning for Medical Imagescited by 10
  30. 2022ML-BPM: Multi-teacher Learning with Bidirectional Photometric Mixing for Open Compound Domain Adaptation in Semantic Segmentationcited by 9
  31. 2022Unsupervised pre-training of graph transformers on patient population graphscited by 9
  32. 2024A Survey on Domain Generalization for Medical Image Analysiscited by 9
  33. 2024SAM-MPA: Applying SAM to Few-shot Medical Image Segmentation using Mask Propagation and Auto-promptingcited by 9
  34. 2025SynPo: Boosting Training-Free Few-Shot Medical Segmentation via High-Quality Negative Promptscited by 9
  35. 2022CUTS: A Deep Learning and Topological Framework for Multigranular Unsupervised Medical Image Segmentationcited by 8
  36. 2023Harmonizing Base and Novel Classes: A Class-Contrastive Approach for Generalized Few-Shot Segmentationcited by 8
  37. 2024ProtoS-ViT: Visual foundation models for sparse self-explainable classificationscited by 8
  38. 2025MAUP: Training-free Multi-center Adaptive Uncertainty-aware Prompting for Cross-domain Few-shot Medical Image Segmentationcited by 8

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