Artificial neural networks for neuroscientists: A primer
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Abstract (arXiv)
Artificial neural networks (ANNs) are essential tools in machine learning that have drawn increasing attention in neuroscience. Besides offering powerful techniques for data analysis, ANNs provide a new approach for neuroscientists to build models for complex behaviors, heterogeneous neural activity and circuit connectivity, as well as to explore optimization in neural systems, in ways that traditional models are not designed for. In this pedagogical Primer, we introduce ANNs and demonstrate how they have been fruitfully deployed to study neuroscientific questions. We first discuss basic concepts and methods of ANNs. Then, with a focus on bringing this mathematical framework closer to neurobiology, we detail how to customize the analysis, structure, and learning of ANNs to better address a wide range of challenges in brain research. To help the readers garner hands-on experience, this Primer is accompanied with tutorial-style code in PyTorch and Jupyter Notebook, covering major topics.
Key facts. Cited by 26 papers in the map (data through 7 Oct 2026). First posted on arXiv 1 Jun 2020.
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Citing papers per year: 2021: 2; 2022: 3; 2023: 4; 2024: 7; 2025: 8; 2026: 2.
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- 2024Orchestrate Latent Expertise: Advancing Online Continual Learning with Multi-Level Supervision and Reverse Self-Distillationcited by 16
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- 2021Slow manifolds in recurrent networks encode working memory efficiently and robustlycited by 1
- 2022Lightweight 3D Convolutional Neural Network for Schizophrenia diagnosis using MRI Images and Ensemble Bagging Classifiercited by 1
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14 more
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- 2025Mechanistic Interpretability of RNNs emulating Hidden Markov Modelscited by 0
- 2025AVM: Towards Structure-Preserving Neural Response Modeling in the Visual Cortex Across Stimuli and Individualscited by 0
- 2026A dimensional R2 regression metriccited by 0
- 2026Effective pruning of task-trained recurrent neural networks using noisy fluctuations and connection rescalingcited by 0
- 2026Effective pruning of task-trained recurrent neural networks using noisy fluctuations and connection rescaling5 Aug 2026
- 2026A dimensional R2 regression metric1 May 2026
- 2025AVM: Towards Structure-Preserving Neural Response Modeling in the Visual Cortex Across Stimuli and Individuals17 Dec 2025
- 2025Mechanistic Interpretability of RNNs emulating Hidden Markov Models29 Oct 2025
- 2025Emergence of hybrid computational dynamics through reinforcement learning13 Oct 2025
- 2025A mathematical theory for understanding when abstract representations emerge in neural networks10 Oct 2025
- 2025Pursuit of biomarkers of brain diseases: Beyond cohort comparisons8 Sep 2025
- 2025Flexible inference for animal learning rules using neural networks4 Sep 2025
- 2025Can Biologically Plausible Temporal Credit Assignment Rules Match BPTT for Neural Similarity? E-prop as an Example7 Jun 2025
- 2025Serious Games: Human-AI Interaction, Evolution, and Coevolution22 May 2025
- 2024Skewed Neuronal Heterogeneity Enhances Efficiency On Various Computing Systems6 Dec 2024
- 2024Network Representation Learning for Biophysical Neural Network Analysis15 Oct 2024
14 more
- 2024Neural timescales from a computational perspective4 Sep 2024
- 2024Disentangling Representations through Multi-task Learning15 Jul 2024
- 2024Items or Relations -- what do Artificial Neural Networks learn?15 Apr 2024
- 2024Orchestrate Latent Expertise: Advancing Online Continual Learning with Multi-Level Supervision and Reverse Self-Distillation30 Mar 2024
- 2024FPGA Deployment of LFADS for Real-time Neuroscience Experiments2 Feb 2024
- 2023How connectivity structure shapes rich and lazy learning in neural circuits12 Oct 2023
- 2023Why Linguistics Will Thrive in the 21st Century: A Reply to Piantadosi (2023)6 Aug 2023
- 2023A Versatile Hub Model For Efficient Information Propagation And Feature Selection5 Jul 2023
- 2023Temporal Conditioning Spiking Latent Variable Models of the Neural Response to Natural Visual Scenes21 Jun 2023
- 2022Scalar Invariant Networks with Zero Bias15 Nov 2022
- 2022Lightweight 3D Convolutional Neural Network for Schizophrenia diagnosis using MRI Images and Ensemble Bagging Classifier5 Nov 2022
- 2022Learning by non-interfering feedback chemical signaling in physical networks22 Mar 2022
- 2021Measuring and modeling the motor system with machine learning22 Mar 2021
- 2021Slow manifolds in recurrent networks encode working memory efficiently and robustly8 Jan 2021
- 2024Disentangling Representations through Multi-task Learning15 Jul 2024
- 2024Orchestrate Latent Expertise: Advancing Online Continual Learning with Multi-Level Supervision and Reverse Self-Distillationcited by 16
- 2023How connectivity structure shapes rich and lazy learning in neural circuitscited by 15
- 2022Learning by non-interfering feedback chemical signaling in physical networkscited by 10
- 2023Why Linguistics Will Thrive in the 21st Century: A Reply to Piantadosi (2023)cited by 9
- 2021Measuring and modeling the motor system with machine learningcited by 7
- 2023Temporal Conditioning Spiking Latent Variable Models of the Neural Response to Natural Visual Scenescited by 4
- 2024Neural timescales from a computational perspectivecited by 3
- 2025A mathematical theory for understanding when abstract representations emerge in neural networkscited by 3
- 2021Slow manifolds in recurrent networks encode working memory efficiently and robustlycited by 1
- 2022Lightweight 3D Convolutional Neural Network for Schizophrenia diagnosis using MRI Images and Ensemble Bagging Classifiercited by 1
- 2022Scalar Invariant Networks with Zero Biascited by 1
- 2024Items or Relations -- what do Artificial Neural Networks learn?cited by 1
12 most cited of 25 All 25 (JSON)
- 2026Effective pruning of task-trained recurrent neural networks using noisy fluctuations and connection rescaling5 Aug 2026
- 2026A dimensional R2 regression metric1 May 2026
- 2025AVM: Towards Structure-Preserving Neural Response Modeling in the Visual Cortex Across Stimuli and Individuals17 Dec 2025
- 2025Mechanistic Interpretability of RNNs emulating Hidden Markov Models29 Oct 2025
- 2025Emergence of hybrid computational dynamics through reinforcement learning13 Oct 2025
- 2025A mathematical theory for understanding when abstract representations emerge in neural networks10 Oct 2025
- 2025Pursuit of biomarkers of brain diseases: Beyond cohort comparisons8 Sep 2025
- 2025Flexible inference for animal learning rules using neural networks4 Sep 2025
- 2025Can Biologically Plausible Temporal Credit Assignment Rules Match BPTT for Neural Similarity? E-prop as an Example7 Jun 2025
- 2025Serious Games: Human-AI Interaction, Evolution, and Coevolution22 May 2025
- 2024Skewed Neuronal Heterogeneity Enhances Efficiency On Various Computing Systems6 Dec 2024
- 2024Network Representation Learning for Biophysical Neural Network Analysis15 Oct 2024
12 newest of 25 All 25 (JSON)