Shape-Aware Organ Segmentation by Predicting Signed Distance Maps
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Abstract (arXiv)
In this work, we propose to resolve the issue existing in current deep learning based organ segmentation systems that they often produce results that do not capture the overall shape of the target organ and often lack smoothness. Since there is a rigorous mapping between the Signed Distance Map (SDM) calculated from object boundary contours and the binary segmentation map, we exploit the feasibility of learning the SDM directly from medical scans. By converting the segmentation task into predicting an SDM, we show that our proposed method retains superior segmentation performance and has better smoothness and continuity in shape. To leverage the complementary information in traditional segmentation training, we introduce an approximated Heaviside function to train the model by predicting SDMs and segmentation maps simultaneously. We validate our proposed models by conducting extensive experiments on a hippocampus segmentation dataset and the public MICCAI 2015 Head and Neck Auto Segmentation Challenge dataset with multiple organs. While our carefully designed backbone 3D segmentation network improves the Dice coefficient by more than 5% compared to current state-of-the-arts, the proposed model with SDM learning produces smoother segmentation results with smaller Hausdorff distance and average surface distance, thus proving the effectiveness of our method.
Key facts. Cited by 41 papers in the map (data through 7 Oct 2026). First posted on arXiv 9 Dec 2019.
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Citing papers per year: 2021: 11; 2022: 9; 2023: 7; 2024: 7; 2025: 4; 2026: 3.
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- 2021SimCVD: Simple Contrastive Voxel-Wise Representation Distillation for Semi-Supervised Medical Image Segmentationcited by 86
- 2021Momentum Contrastive Voxel-wise Representation Learning for Semi-supervised Volumetric Medical Image Segmentationcited by 49
- 2023Rethinking Semi-Supervised Medical Image Segmentation: A Variance-Reduction Perspectivecited by 43
- 2022Mine yOur owN Anatomy: Revisiting Medical Image Segmentation with Extremely Limited Labelscited by 30
- 2024Centerline Boundary Dice Loss for Vascular Segmentationcited by 27
- 2024FlowSDF: Flow Matching for Medical Image Segmentation Using Distance Transformscited by 25
- 2022NaviAirway: a Bronchiole-sensitive Deep Learning-based Airway Segmentation Pipelinecited by 17
- 2022BREAK: Bronchi Reconstruction by gEodesic transformation And sKeleton embeddingcited by 16
- 2021FDA: Feature Decomposition and Aggregation for Robust Airway Segmentationcited by 12
- 2022JPerceiver: Joint Perception Network for Depth, Pose and Layout Estimation in Driving Scenescited by 11
- 2023Multi-site, Multi-domain Airway Tree Modeling (ATM'22): A Public Benchmark for Pulmonary Airway Segmentationcited by 9
- 2023Score-Based Generative Models for Medical Image Segmentation using Signed Distance Functionscited by 8
29 more
- 2022Contour-Aware Equipotential Learning for Semantic Segmentationcited by 6
- 2022Leveraging Labeling Representations in Uncertainty-based Semi-supervised Segmentationcited by 5
- 2024SiNGR: Brain Tumor Segmentation via Signed Normalized Geodesic Transform Regressioncited by 4
- 2024Shape-intensity knowledge distillation for robust medical image segmentationcited by 4
- 2025Semi-MoE: Mixture-of-Experts meets Semi-Supervised Histopathology Segmentationcited by 4
- 2021CleftNet: Augmented Deep Learning for Synaptic Cleft Detection from Brain Electron Microscopycited by 3
- 2021Semantic-Aware Contrastive Learning for Multi-object Medical Image Segmentationcited by 3
- 2022Boundary-aware Information Maximization for Self-supervised Medical Image Segmentationcited by 2
- 2022Shape constrained CNN for segmentation guided prediction of myocardial shape and pose parameters in cardiac MRIcited by 2
- 2022Differentiable Topology-Preserved Distance Transform for Pulmonary Airway Segmentationcited by 2
- 2023Multi-organ segmentation: a progressive exploration of learning paradigms under scarce annotationcited by 2
- 2023Hybrid Dual Mean-Teacher Network With Double-Uncertainty Guidance for Semi-Supervised Segmentation of MRI Scanscited by 2
- 2024Segment as You Wish -- Free-Form Language-Based Segmentation for Medical Imagescited by 2
- 2025A Dual-Task Synergy-Driven Generalization Framework for Pancreatic Cancer Segmentation in CT Scanscited by 2
- 2021Pushing the Envelope of Thin Crack Detectioncited by 1
- 2021HCDG: A Hierarchical Consistency Framework for Domain Generalization on Medical Image Segmentationcited by 1
- 2023FourierLoss: Shape-Aware Loss Function with Fourier Descriptorscited by 1
- 2024Uncertainty-aware retinal layer segmentation in OCT through probabilistic signed distance functionscited by 1
- 2021Brain Surface Reconstruction from MRI Images Based on Segmentation Networks Applying Signed Distance Mapscited by 0
- 2021Residual Moment Loss for Medical Image Segmentationcited by 0
- 2021A Dense Siamese U-Net trained with Edge Enhanced 3D IOU Loss for Image Co-segmentationcited by 0
- 2021Dual Shape Guided Segmentation Network for Organs-at-Risk in Head and Neck CT Imagescited by 0
- 2023Learning to In-paint: Domain Adaptive Shape Completion for 3D Organ Segmentationcited by 0
- 2024Image-level Regression for Uncertainty-aware Retinal Image Segmentationcited by 0
- 2025Neovascularization Segmentation via a Multilateral Interaction-Enhanced Graph Convolutional Networkcited by 0
- 2025FocusSDF: Boundary-Aware Learning for Medical Image Segmentation via Signed Distance Supervisioncited by 0
- 2026SC-MFJ: A Simple Haptic Quality Metric for Medical Image Segmentationcited by 0
- 2026From Gradient Clipping to Structural Refinement: Improving DPSGD for Medical Image Segmentationcited by 0
- 2026PSP: Harnessing Position and Shape Priors for Cross-Domain Few-Shot Medical Image Segmentationcited by 0
- 2026PSP: Harnessing Position and Shape Priors for Cross-Domain Few-Shot Medical Image Segmentation27 Jun 2026
- 2026From Gradient Clipping to Structural Refinement: Improving DPSGD for Medical Image Segmentation19 Jun 2026
- 2026SC-MFJ: A Simple Haptic Quality Metric for Medical Image Segmentation4 Jun 2026
- 2025FocusSDF: Boundary-Aware Learning for Medical Image Segmentation via Signed Distance Supervision14 Nov 2025
- 2025Semi-MoE: Mixture-of-Experts meets Semi-Supervised Histopathology Segmentation17 Sep 2025
- 2025Neovascularization Segmentation via a Multilateral Interaction-Enhanced Graph Convolutional Network5 Aug 2025
- 2025A Dual-Task Synergy-Driven Generalization Framework for Pancreatic Cancer Segmentation in CT Scans3 May 2025
- 2024Uncertainty-aware retinal layer segmentation in OCT through probabilistic signed distance functions6 Dec 2024
- 2024Segment as You Wish -- Free-Form Language-Based Segmentation for Medical Images2 Oct 2024
- 2024Shape-intensity knowledge distillation for robust medical image segmentation26 Sep 2024
- 2024Centerline Boundary Dice Loss for Vascular Segmentation1 Jul 2024
- 2024FlowSDF: Flow Matching for Medical Image Segmentation Using Distance Transforms28 May 2024
29 more
- 2024Image-level Regression for Uncertainty-aware Retinal Image Segmentation27 May 2024
- 2024SiNGR: Brain Tumor Segmentation via Signed Normalized Geodesic Transform Regression27 May 2024
- 2023FourierLoss: Shape-Aware Loss Function with Fourier Descriptors21 Sep 2023
- 2023Learning to In-paint: Domain Adaptive Shape Completion for 3D Organ Segmentation17 Aug 2023
- 2023Score-Based Generative Models for Medical Image Segmentation using Signed Distance Functions10 Mar 2023
- 2023Multi-site, Multi-domain Airway Tree Modeling (ATM'22): A Public Benchmark for Pulmonary Airway Segmentation10 Mar 2023
- 2023Hybrid Dual Mean-Teacher Network With Double-Uncertainty Guidance for Semi-Supervised Segmentation of MRI Scans9 Mar 2023
- 2023Multi-organ segmentation: a progressive exploration of learning paradigms under scarce annotation7 Feb 2023
- 2023Rethinking Semi-Supervised Medical Image Segmentation: A Variance-Reduction Perspective3 Feb 2023
- 2022Contour-Aware Equipotential Learning for Semantic Segmentation1 Oct 2022
- 2022Mine yOur owN Anatomy: Revisiting Medical Image Segmentation with Extremely Limited Labels27 Sep 2022
- 2022Differentiable Topology-Preserved Distance Transform for Pulmonary Airway Segmentation17 Sep 2022
- 2022JPerceiver: Joint Perception Network for Depth, Pose and Layout Estimation in Driving Scenes16 Jul 2022
- 2022Leveraging Labeling Representations in Uncertainty-based Semi-supervised Segmentation10 Mar 2022
- 2022NaviAirway: a Bronchiole-sensitive Deep Learning-based Airway Segmentation Pipeline8 Mar 2022
- 2022Shape constrained CNN for segmentation guided prediction of myocardial shape and pose parameters in cardiac MRI2 Mar 2022
- 2022Boundary-aware Information Maximization for Self-supervised Medical Image Segmentation4 Feb 2022
- 2022BREAK: Bronchi Reconstruction by gEodesic transformation And sKeleton embedding29 Jan 2022
- 2021Dual Shape Guided Segmentation Network for Organs-at-Risk in Head and Neck CT Images23 Oct 2021
- 2021HCDG: A Hierarchical Consistency Framework for Domain Generalization on Medical Image Segmentation13 Sep 2021
- 2021FDA: Feature Decomposition and Aggregation for Robust Airway Segmentation7 Sep 2021
- 2021A Dense Siamese U-Net trained with Edge Enhanced 3D IOU Loss for Image Co-segmentation17 Aug 2021
- 2021SimCVD: Simple Contrastive Voxel-Wise Representation Distillation for Semi-Supervised Medical Image Segmentation13 Aug 2021
- 2021Residual Moment Loss for Medical Image Segmentation27 Jun 2021
- 2021Semantic-Aware Contrastive Learning for Multi-object Medical Image Segmentation3 Jun 2021
- 2021Momentum Contrastive Voxel-wise Representation Learning for Semi-supervised Volumetric Medical Image Segmentation14 May 2021
- 2021Brain Surface Reconstruction from MRI Images Based on Segmentation Networks Applying Signed Distance Maps9 Apr 2021
- 2021CleftNet: Augmented Deep Learning for Synaptic Cleft Detection from Brain Electron Microscopy12 Jan 2021
- 2021Pushing the Envelope of Thin Crack Detection9 Jan 2021
- 2021SimCVD: Simple Contrastive Voxel-Wise Representation Distillation for Semi-Supervised Medical Image Segmentationcited by 86
- 2021Momentum Contrastive Voxel-wise Representation Learning for Semi-supervised Volumetric Medical Image Segmentationcited by 49
- 2023Rethinking Semi-Supervised Medical Image Segmentation: A Variance-Reduction Perspectivecited by 43
- 2022Mine yOur owN Anatomy: Revisiting Medical Image Segmentation with Extremely Limited Labelscited by 30
- 2024Centerline Boundary Dice Loss for Vascular Segmentationcited by 27
- 2022NaviAirway: a Bronchiole-sensitive Deep Learning-based Airway Segmentation Pipelinecited by 17
- 2022BREAK: Bronchi Reconstruction by gEodesic transformation And sKeleton embeddingcited by 16
- 2021FDA: Feature Decomposition and Aggregation for Robust Airway Segmentationcited by 12
- 2023Multi-site, Multi-domain Airway Tree Modeling (ATM'22): A Public Benchmark for Pulmonary Airway Segmentationcited by 9
- 2022Contour-Aware Equipotential Learning for Semantic Segmentationcited by 6
- 2022Leveraging Labeling Representations in Uncertainty-based Semi-supervised Segmentationcited by 5
- 2024SiNGR: Brain Tumor Segmentation via Signed Normalized Geodesic Transform Regressioncited by 4
12 most cited of 37 All 37 (JSON)
- 2026PSP: Harnessing Position and Shape Priors for Cross-Domain Few-Shot Medical Image Segmentation27 Jun 2026
- 2026From Gradient Clipping to Structural Refinement: Improving DPSGD for Medical Image Segmentation19 Jun 2026
- 2026SC-MFJ: A Simple Haptic Quality Metric for Medical Image Segmentation4 Jun 2026
- 2025FocusSDF: Boundary-Aware Learning for Medical Image Segmentation via Signed Distance Supervision14 Nov 2025
- 2025Neovascularization Segmentation via a Multilateral Interaction-Enhanced Graph Convolutional Network5 Aug 2025
- 2025A Dual-Task Synergy-Driven Generalization Framework for Pancreatic Cancer Segmentation in CT Scans3 May 2025
- 2024Uncertainty-aware retinal layer segmentation in OCT through probabilistic signed distance functions6 Dec 2024
- 2024Segment as You Wish -- Free-Form Language-Based Segmentation for Medical Images2 Oct 2024
- 2024Shape-intensity knowledge distillation for robust medical image segmentation26 Sep 2024
- 2024Centerline Boundary Dice Loss for Vascular Segmentation1 Jul 2024
- 2024Image-level Regression for Uncertainty-aware Retinal Image Segmentation27 May 2024
- 2024SiNGR: Brain Tumor Segmentation via Signed Normalized Geodesic Transform Regression27 May 2024
12 newest of 37 All 37 (JSON)