Informed Machine Learning -- A Taxonomy and Survey of Integrating Knowledge into Learning Systems
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Abstract (arXiv)
Despite its great success, machine learning can have its limits when dealing with insufficient training data. A potential solution is the additional integration of prior knowledge into the training process which leads to the notion of informed machine learning. In this paper, we present a structured overview of various approaches in this field. We provide a definition and propose a concept for informed machine learning which illustrates its building blocks and distinguishes it from conventional machine learning. We introduce a taxonomy that serves as a classification framework for informed machine learning approaches. It considers the source of knowledge, its representation, and its integration into the machine learning pipeline. Based on this taxonomy, we survey related research and describe how different knowledge representations such as algebraic equations, logic rules, or simulation results can be used in learning systems. This evaluation of numerous papers on the basis of our taxonomy uncovers key methods in the field of informed machine learning.
Key facts. Cited by 205 papers in the map (data through 14 Oct 2026). First posted on arXiv 29 Mar 2019.
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Citing papers per year: 2021: 32; 2022: 37; 2023: 38; 2024: 47; 2025: 26; 2026: 25.
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- 2021Characterizing possible failure modes in physics-informed neural networkscited by 643
- 2022A Survey of Knowledge Enhanced Pre-trained Language Modelscited by 76
- 2022When Physics Meets Machine Learning: A Survey of Physics-Informed Machine Learningcited by 65
- 2021Learning in Sinusoidal Spaces with Physics-Informed Neural Networkscited by 62
- 2021Physics-Integrated Variational Autoencoders for Robust and Interpretable Generative Modelingcited by 59
- 2021Incorporating Domain Knowledge into Deep Neural Networkscited by 56
- 2021Explanation-Based Human Debugging of NLP Models: A Surveycited by 53
- 2022Leveraging Explanations in Interactive Machine Learning: An Overviewcited by 53
- 2022Deep Learning with Logical Constraintscited by 44
- 2021A Survey on Neural-symbolic Learning Systemscited by 39
- 2022Machine Learning in Aerodynamic Shape Optimizationcited by 39
- 2022A Survey on Explainable Anomaly Detectioncited by 39
38 more
- 2022Is Neuro-Symbolic AI Meeting its Promise in Natural Language Processing? A Structured Reviewcited by 38
- 2022Compute-Efficient Deep Learning: Algorithmic Trends and Opportunitiescited by 38
- 2022Towards Data-and Knowledge-Driven Artificial Intelligence: A Survey on Neuro-Symbolic Computingcited by 35
- 2021Constructing Neural Network-Based Models for Simulating Dynamical Systemscited by 31
- 2021Latent Space Data Assimilation by using Deep Learningcited by 30
- 2023TABLET: Learning From Instructions For Tabular Datacited by 28
- 2022Adaptive Self-supervision Algorithms for Physics-informed Neural Networkscited by 24
- 2022PIXEL: Physics-Informed Cell Representations for Fast and Accurate PDE Solverscited by 22
- 2021Injecting Knowledge in Data-driven Vehicle Trajectory Predictorscited by 18
- 2022Recognizing Object by Components with Human Prior Knowledge Enhances Adversarial Robustness of Deep Neural Networkscited by 18
- 2021Physically Consistent Neural Networks for building thermal modeling: theory and analysiscited by 17
- 2021Explainable Machine Learning with Prior Knowledge: An Overviewcited by 15
- 2023Toward Physically Plausible Data-Driven Models: A Novel Neural Network Approach to Symbolic Regressioncited by 14
- 2023A spectrum of physics-informed Gaussian processes for regression in engineeringcited by 14
- 2024Knowledge-guided Machine Learning: Current Trends and Future Prospectscited by 14
- 2022Finite Element Method-enhanced Neural Network for Forward and Inverse Problemscited by 13
- 2024Geometry-Informed Neural Networkscited by 12
- 2024Physics-Enhanced Machine Learning: a position paper for dynamical systems investigationscited by 12
- 2024Generalizing 6-DoF Grasp Detection via Domain Prior Knowledgecited by 11
- 2025Evolutionary Optimization of Physics-Informed Neural Networks: Evo-PINN Frontiers and Opportunitiescited by 11
- 2022Knowledge-augmented Deep Learning and Its Applications: A Surveycited by 10
- 2023GLUECons: A Generic Benchmark for Learning Under Constraintscited by 9
- 2024ULLER: A Unified Language for Learning and Reasoningcited by 9
- 2021AI Descartes: Combining Data and Theory for Derivable Scientific Discoverycited by 8
- 2021A coarse space acceleration of deep-DDMcited by 8
- 2024Med-Real2Sim: Non-Invasive Medical Digital Twins using Physics-Informed Self-Supervised Learningcited by 8
- 2024Naturally Supervised 3D Visual Grounding with Language-Regularized Concept Learnerscited by 8
- 2022Requirements Engineering for Machine Learning: A Review and Reflectioncited by 7
- 2022Deep Grey-Box Modeling With Adaptive Data-Driven Models Toward Trustworthy Estimation of Theory-Driven Modelscited by 7
- 2023Unleashing the Power of Shared Label Structures for Human Activity Recognitioncited by 7
- 2024KID-PPG: Knowledge Informed Deep Learning for Extracting Heart Rate from a Smartwatchcited by 7
- 2024ATLAS: Adapter-Based Multi-Modal Continual Learning with a Two-Stage Learning Strategycited by 7
- 2025Symbolic Knowledge Extraction and Injection with Sub-symbolic Predictors: A Systematic Literature Reviewcited by 7
- 2022Causal Discovery and Knowledge Injection for Contestable Neural Networks (with Appendices)cited by 6
- 2023Navigating Alignment for Non-identical Client Class Sets: A Label Name-Anchored Federated Learning Frameworkcited by 6
- 2023From Model-Based to Data-Driven Simulation: Challenges and Trends in Autonomous Drivingcited by 6
- 2023Physics Inspired Hybrid Attention for SAR Target Recognitioncited by 6
- 2021Multicriteria interpretability driven Deep Learningcited by 5
50 most cited of 205 All 205 (JSON)
- 2026Joint Embedding with Dynamic Integration network (JEDI-net)12 Oct 2026
- 2026KITE: A Knowledge-Injected Temporal Encoder for Time-Series Event Forecasting8 Oct 2026
- 2026Co-PiLOT: Constrained Physics-Informed Latent Optimization for Target-Driven Inverse Design29 Sep 2026
- 2026Data-Driven Learning of Unknown Nonlinear Differential Equations Using Functional Analysis3 Sep 2026
- 2026Anatomy-Informed Neural Networks: Encoding Anatomic Priors in Loss and Architecture, with an SE(3) Formulation of Guidewire-Induced Aortoiliac Deformation21 Aug 2026
- 2026When does fusing hand-crafted knowledge with learned representations pay? A cost-normalized benchmark of stacking, substitution, and interference21 Aug 2026
- 2026Knowledge-guided Pattern Discovery via Coupled Tensor Factorizations13 Aug 2026
- 2026Accelerating nanodrug development in continuous flow systems using informed prediction models based on low-cost surrogate nanoparticles6 Aug 2026
- 2026The RAIL Principles for Neurosymbolic AI: Reasoning, Assurances, Interfacing and Learning4 Aug 2026
- 2026SHiPPO: Recurrent Memory with Transported Polynomial Projections3 Jul 2026
- 2026Domain Knowledge Based Temporal-Spatial Graph Convolution Network for ECG Recognition1 Jul 2026
- 2026The FIL Hypothesis: Inductive Biases Help with Kernel Engineering29 Jun 2026
38 more
- 2026Data Enrichment for Symbolic Regression Using Diffusion Models31 May 2026
- 2026Estimation of Motor Unit Parameters from Surface Electromyograms using an Informed Autoencoder8 May 2026
- 2026Using Large Language Models and Knowledge Graphs to Improve the Interpretability of Machine Learning Models in Manufacturing17 Apr 2026
- 2026Expert-Guided Class-Conditional Goodness-of-Fit Scores for Interpretable Classification with Informative Missingness: An Application to Seismic Monitoring16 Apr 2026
- 2026A Hybrid Intelligent Framework for Uncertainty-Aware Condition Monitoring of Industrial Systems10 Apr 2026
- 2026Enhancing the Reliability of Medical AI through Expert-guided Uncertainty Modeling2 Apr 2026
- 2026Informed Machine Learning with Knowledge Landmarks31 Mar 2026
- 2026Gaussian Process Regression-based Knowledge Distillation Framework for Simultaneous Prediction of Physical and Mechanical Properties of Epoxy Polymers12 Mar 2026
- 2026Simultaneous estimation of multiple discrete unimodal distributions under stochastic order constraints12 Mar 2026
- 2026Knowledge-informed Bidding with Dual-process Control for Online Advertising5 Mar 2026
- 2026Structured Hybrid Mechanistic Models for Robust Estimation of Time-Dependent Intervention Outcomes11 Feb 2026
- 2026Knowledge Integration in Differentiable Models: A Comparative Study of Data-Driven, Soft-Constrained, and Hard-Constrained Paradigms for Identification and Control of the Single Machine Infinite Bus System10 Feb 2026
- 2026Aortic Valve Disease Screening from PPG via Physiology-Guided Self-Supervised Learning4 Feb 2026
- 2025LVLM-Aided Alignment of Task-Specific Vision Models26 Dec 2025
- 2025Neurosymbolic Inference On Foundation Models For Remote Sensing Text-to-image Retrieval With Complex Queries16 Dec 2025
- 2025Neurocircuitry-Inspired Hierarchical Graph Causal Attention Networks for Explainable Depression Identification18 Nov 2025
- 2025Generative AI Meets 6G and Beyond: Diffusion Models for Semantic Communications11 Nov 2025
- 2025LieSolver: PDE-Constrained Learning for IBVPs via Lie Symmetries29 Oct 2025
- 2025Complexity Dependent Error Rates for Physics-informed Statistical Learning via the Small-ball Method27 Oct 2025
- 2025Informed Learning for Estimating Drought Stress at Fine-Scale Resolution Enables Accurate Yield Prediction21 Oct 2025
- 2025R2T: Rule-Encoded Loss Functions for Sequence Tagging in Low-Resource Languages12 Oct 2025
- 2025PHASE: Physics-Integrated, Heterogeneity-Aware Surrogates for Scientific Simulations27 Sep 2025
- 2025Quantitative Estimation of Target Task Performance from Unsupervised Pretext Task in Semi/Self-Supervised Learning10 Aug 2025
- 2025ViPro-2: Unsupervised State Estimation via Integrated Dynamics for Guiding Video Prediction8 Aug 2025
- 2025Neural Ordinary Differential Equations for Learning and Extrapolating System Dynamics Across Bifurcations25 Jul 2025
- 2025Small Data Explainer -- The impact of small data methods in everyday life15 Jul 2025
- 2025Adversarial Disentanglement by Backpropagation with Physics-Informed Variational Autoencoder16 Jun 2025
- 2025Reliable and efficient inverse analysis using physics-informed neural networks with normalized distance functions and adaptive weight tuning25 Apr 2025
- 2025Neuro-Evolutionary Approach to Physics-Aware Symbolic Regression23 Apr 2025
- 2025Uncertainty-Aware Trajectory Prediction via Rule-Regularized Heteroscedastic Deep Classification17 Apr 2025
- 2025A discrete physics-informed training for projection-based reduced order models with neural networks31 Mar 2025
- 2025A Language Anchor-Guided Method for Robust Noisy Domain Generalization21 Mar 2025
- 2025A Learnability Analysis on Neuro-Symbolic Learning21 Mar 2025
- 2025Meta Learning not to Learn: Robustly Informing Meta-Learning under Nuisance-Varying Families6 Mar 2025
- 2025SUSTeR: Sparse Unstructured Spatio Temporal Reconstruction on Traffic Prediction24 Feb 2025
- 2025Factor Graph-based Interpretable Neural Networks20 Feb 2025
- 2025Symbolic Knowledge Extraction and Injection with Sub-symbolic Predictors: A Systematic Literature Review23 Jan 2025
- 2025SEANN: A Domain-Informed Neural Network for Epidemiological Insights17 Jan 2025
50 newest of 205 All 205 (JSON)
- 2022Is Neuro-Symbolic AI Meeting its Promise in Natural Language Processing? A Structured Reviewcited by 38
- 2023Learning by Applying: A General Framework for Mathematical Reasoning via Enhancing Explicit Knowledge Learningcited by 5
- 2024Combining Machine Learning and Ontology: A Systematic Literature Reviewcited by 3
- 2024Improving Neural-based Classification with Logical Background Knowledgecited by 2
- 2026The RAIL Principles for Neurosymbolic AI: Reasoning, Assurances, Interfacing and Learningcited by 1
- 2023Causal Reasoning through Two Layers of Cognition for Improving Generalization in Visual Question Answeringcited by 0
- 2024A Complexity Map of Probabilistic Reasoning for Neurosymbolic Classification Techniquescited by 0
- 2026The RAIL Principles for Neurosymbolic AI: Reasoning, Assurances, Interfacing and Learning4 Aug 2026
- 2024A Complexity Map of Probabilistic Reasoning for Neurosymbolic Classification Techniques12 Apr 2024
- 2024Improving Neural-based Classification with Logical Background Knowledge20 Feb 2024
- 2024Combining Machine Learning and Ontology: A Systematic Literature Review15 Jan 2024
- 2023Causal Reasoning through Two Layers of Cognition for Improving Generalization in Visual Question Answering9 Oct 2023
- 2023Learning by Applying: A General Framework for Mathematical Reasoning via Enhancing Explicit Knowledge Learning11 Feb 2023
- 2022Is Neuro-Symbolic AI Meeting its Promise in Natural Language Processing? A Structured Review24 Feb 2022
- 2021Characterizing possible failure modes in physics-informed neural networkscited by 643
- 2022A Survey of Knowledge Enhanced Pre-trained Language Modelscited by 76
- 2022When Physics Meets Machine Learning: A Survey of Physics-Informed Machine Learningcited by 65
- 2021Learning in Sinusoidal Spaces with Physics-Informed Neural Networkscited by 62
- 2021Physics-Integrated Variational Autoencoders for Robust and Interpretable Generative Modelingcited by 59
- 2021Incorporating Domain Knowledge into Deep Neural Networkscited by 56
- 2021Explanation-Based Human Debugging of NLP Models: A Surveycited by 53
- 2022Leveraging Explanations in Interactive Machine Learning: An Overviewcited by 53
- 2022Deep Learning with Logical Constraintscited by 44
- 2021A Survey on Neural-symbolic Learning Systemscited by 39
- 2022Machine Learning in Aerodynamic Shape Optimizationcited by 39
- 2022A Survey on Explainable Anomaly Detectioncited by 39
12 most cited of 194 All 194 (JSON)
- 2026Joint Embedding with Dynamic Integration network (JEDI-net)12 Oct 2026
- 2026KITE: A Knowledge-Injected Temporal Encoder for Time-Series Event Forecasting8 Oct 2026
- 2026Data-Driven Learning of Unknown Nonlinear Differential Equations Using Functional Analysis3 Sep 2026
- 2026Anatomy-Informed Neural Networks: Encoding Anatomic Priors in Loss and Architecture, with an SE(3) Formulation of Guidewire-Induced Aortoiliac Deformation21 Aug 2026
- 2026When does fusing hand-crafted knowledge with learned representations pay? A cost-normalized benchmark of stacking, substitution, and interference21 Aug 2026
- 2026Knowledge-guided Pattern Discovery via Coupled Tensor Factorizations13 Aug 2026
- 2026Accelerating nanodrug development in continuous flow systems using informed prediction models based on low-cost surrogate nanoparticles6 Aug 2026
- 2026SHiPPO: Recurrent Memory with Transported Polynomial Projections3 Jul 2026
- 2026Domain Knowledge Based Temporal-Spatial Graph Convolution Network for ECG Recognition1 Jul 2026
- 2026The FIL Hypothesis: Inductive Biases Help with Kernel Engineering29 Jun 2026
- 2026Estimation of Motor Unit Parameters from Surface Electromyograms using an Informed Autoencoder8 May 2026
- 2026Using Large Language Models and Knowledge Graphs to Improve the Interpretability of Machine Learning Models in Manufacturing17 Apr 2026
12 newest of 194 All 194 (JSON)