End-to-end Training for Whole Image Breast Cancer Diagnosis using An All Convolutional Design
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Abstract (arXiv)
We develop an end-to-end training algorithm for whole-image breast cancer diagnosis based on mammograms. It requires lesion annotations only at the first stage of training. After that, a whole image classifier can be trained using only image level labels. This greatly reduced the reliance on lesion annotations. Our approach is implemented using an all convolutional design that is simple yet provides superior performance in comparison with the previous methods. On DDSM, our best single-model achieves a per-image AUC score of 0.88 and three-model averaging increases the score to 0.91. On INbreast, our best single-model achieves a per-image AUC score of 0.96. Using DDSM as benchmark, our models compare favorably with the current state-of-the-art. We also demonstrate that a whole image model trained on DDSM can be easily transferred to INbreast without using its lesion annotations and using only a small amount of training data. Code availability: https://github.com/lishen/end2end-all-conv
Key facts. Cited by 88 papers in the map (data through 14 Oct 2026). First posted on arXiv 15 Nov 2017.
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Citing papers per year: 2021: 25; 2022: 21; 2023: 13; 2024: 7; 2025: 13; 2026: 9.
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- 2021Do Feature Attribution Methods Correctly Attribute Features?cited by 98
- 2022Selection by Prediction with Conformal p-valuescited by 69
- 2021Memory-aware curriculum federated learning for breast cancer classificationcited by 20
- 2021Machine Learning Towards Intelligent Systems: Applications, Challenges, and Opportunitiescited by 14
- 2021Breast Cancer Diagnosis in Two-View Mammography Using End-to-End Trained EfficientNet-Based Convolutional Networkcited by 13
- 2021Detection and severity classification of COVID-19 in CT images using deep learningcited by 12
- 2022Multi-view Local Co-occurrence and Global Consistency Learning Improve Mammogram Classification Generalisationcited by 12
- 2022Domain generalization in deep learning-based mass detection in mammography: A large-scale multi-center studycited by 10
- 2022Meta Ordinal Regression Forest for Medical Image Classification with Ordinal Labelscited by 7
- 2022Multi-View Hypercomplex Learning for Breast Cancer Screeningcited by 7
- 2023MammoDG: Generalisable Deep Learning Breaks the Limits of Cross-Domain Multi-Center Breast Cancer Screeningcited by 7
- 2021MEDUSA: Multi-scale Encoder-Decoder Self-Attention Deep Neural Network Architecture for Medical Image Analysiscited by 6
38 more
- 2022Three Applications of Conformal Prediction for Rating Breast Density in Mammographycited by 6
- 2023Attention-Map Augmentation for Hypercomplex Breast Cancer Classificationcited by 6
- 2023Generalizing Medical Image Representations via Quaternion Wavelet Networkscited by 6
- 2025Efficient Breast and Ovarian Cancer Classification via ViT-Based Preprocessing and Transfer Learningcited by 6
- 2021Beyond Fine-tuning: Classifying High Resolution Mammograms using Function-Preserving Transformationscited by 5
- 2022Breast Cancer Classification using Deep Learned Features Boosted with Handcrafted Featurescited by 5
- 2022Estimating and Controlling for Equalized Odds via Sensitive Attribute Predictorscited by 5
- 2022Learning to diagnose common thorax diseases on chest radiographs from radiology reports in Vietnamesecited by 5
- 2023Detection of Mild Cognitive Impairment Using Facial Features in Video Conversationscited by 5
- 2024Decoupling Feature Extraction and Classification Layers for Calibrated Neural Networkscited by 5
- 2021Meta-repository of screening mammography classifierscited by 4
- 2021Multi-task fusion for improving mammography screening data classificationcited by 4
- 2022What is Your Metric Telling You? Evaluating Classifier Calibration under Context-Specific Definitions of Reliabilitycited by 4
- 2023Leveraging Transformers to Improve Breast Cancer Classification and Risk Assessment with Multi-modal and Longitudinal Datacited by 4
- 2021Low-Regret Active learningcited by 3
- 2021A Real Use Case of Semi-Supervised Learning for Mammogram Classification in a Local Clinic of Costa Ricacited by 3
- 2022Calibrating Histopathology Image Classifiers using Label Smoothingcited by 3
- 2023On the Feasibility of Machine Learning Augmented Magnetic Resonance for Point-of-Care Identification of Diseasecited by 3
- 2023MDF-Net for abnormality detection by fusing X-rays with clinical datacited by 3
- 2023The effect of data augmentation and 3D-CNN depth on Alzheimer's Disease detectioncited by 3
- 2024Prototype-based Interpretable Breast Cancer Prediction Models: Analysis and Challengescited by 3
- 2025Augmented Intelligence for Multimodal Virtual Biopsy in Breast Cancer Using Generative Artificial Intelligencecited by 3
- 2025Balancing Two Classifiers via A Simplex ETF Structure for Model Calibrationcited by 3
- 2021Invertible Residual Network with Regularization for Effective Medical Image Segmentationcited by 2
- 2021Deep Curriculum Learning in Task Space for Multi-Class Based Mammography Diagnosiscited by 2
- 2021Gradient Frequency Modulation for Visually Explaining Video Understanding Modelscited by 2
- 2022Towards Clinical Practice: Design and Implementation of Convolutional Neural Network-Based Assistive Diagnosis System for COVID-19 Case Detection from Chest X-Ray Imagescited by 2
- 2023On the Within-Group Fairness of Screening Classifierscited by 2
- 2025Dynamic Residual Encoding with Slide-Level Contrastive Learning for End-to-End Whole Slide Image Representationcited by 2
- 2021Interpretable COVID-19 Chest X-Ray Classification via Orthogonality Constraintcited by 1
- 2021Research on the Detection Method of Breast Cancer Deep Convolutional Neural Network Based on Computer Aidcited by 1
- 2021An XAI Approach to Deep Learning Models in the Detection of DCIScited by 1
- 2021Multimodal Breast Lesion Classification Using Cross-Attention Deep Networkscited by 1
- 2021Unsupervised multi-latent space reinforcement learning framework for video summarization in ultrasound imagingcited by 1
- 2021A Teacher-Student Markov Decision Process-based Framework for Online Correctional Learningcited by 1
- 2022Machine vision for vial positioning detection toward the safe automation of material synthesiscited by 1
- 2022Deep Learning Hyperparameter Optimization for Breast Mass Detection in Mammogramscited by 1
- 2022Slice-level Detection of Intracranial Hemorrhage on CT Using Deep Descriptors of Adjacent Slicescited by 1
50 most cited of 88 All 88 (JSON)
- 2026Lesion-Aware Attention for Mammography Segmentation with Heterogeneous Supervision11 Oct 2026
- 2026M3D-Net: Hierarchical Coordination of Spatial Context, Feature Reuse, and Differential Attention for Mammography Classification23 Sep 2026
- 2026Gradient-Based Latent Decomposition Reveals Mechanisms of Feature Degradation in Weakly Supervised Mammography24 Jul 2026
- 2026A Diagnostic Gap Framework for Evaluating Reconstruction Fidelity in Weakly Supervised Mammography22 Jul 2026
- 2026Unsupervised Domain Adaptation for Calcification Classification in Mammography Across Multi-Site Datasets7 Jul 2026
- 2026Deep Neural Networks with Ordinal Loss for Medical Applications24 Jun 2026
- 2026MAM-CLIP: Vision-Language Pretraining on Mammography Atlases for BI-RADS Classification19 May 2026
- 2026Evaluating Federated Learning approaches for mammography under breast density heterogeneity9 May 2026
- 2026LUMINA: A Multi-Vendor Mammography Benchmark with Energy Harmonization Protocol15 Mar 2026
- 2025OncoVision: Integrating Mammography and Clinical Data through Attention-Driven Multimodal AI for Enhanced Breast Cancer Diagnosis24 Nov 2025
- 2025Dynamic Residual Encoding with Slide-Level Contrastive Learning for End-to-End Whole Slide Image Representation7 Nov 2025
- 2025Region-of-Interest Augmentation for Mammography Classification under Patient-Level Cross-Validation24 Sep 2025
38 more
- 2025Efficient Breast and Ovarian Cancer Classification via ViT-Based Preprocessing and Transfer Learning23 Sep 2025
- 2025Cross-Attention Multimodal Fusion for Breast Cancer Diagnosis: Integrating Mammography and Clinical Data with Explainability21 Aug 2025
- 2025MAMBO: High-Resolution Generative Approach for Mammography Images10 Jun 2025
- 2025Balancing Two Classifiers via A Simplex ETF Structure for Model Calibration14 Apr 2025
- 2025A Multi-Modal AI System for Screening Mammography: Integrating 2D and 3D Imaging to Improve Breast Cancer Detection in a Prospective Clinical Study8 Apr 2025
- 2025Optimizing Breast Cancer Detection in Mammograms: A Comprehensive Study of Transfer Learning, Resolution Reduction, and Multi-View Classification25 Mar 2025
- 2025Efficient Multi-scale Masked Autoencoders with Hybrid-Attention Mechanism for Breast Lesion Classification10 Mar 2025
- 2025Revisiting Invariant Learning for Out-of-Domain Generalization on Multi-Site Mammogram Datasets9 Mar 2025
- 2025Augmented Intelligence for Multimodal Virtual Biopsy in Breast Cancer Using Generative Artificial Intelligence31 Jan 2025
- 2025Bridging Contrastive Learning and Domain Adaptation: Theoretical Perspective and Practical Application28 Jan 2025
- 2024A Decade of Deep Learning: A Survey on The Magnificent Seven13 Dec 2024
- 2024MamT4: Multi-view Attention Networks for Mammography Cancer Classification3 Nov 2024
- 2024Evaluating Deep Learning Models for Breast Cancer Classification: A Comparative Study29 Aug 2024
- 2024Interpretable breast cancer classification using CNNs on mammographic images23 Aug 2024
- 2024A training regime to learn unified representations from complementary breast imaging modalities16 Aug 2024
- 2024Decoupling Feature Extraction and Classification Layers for Calibrated Neural Networks2 May 2024
- 2024Prototype-based Interpretable Breast Cancer Prediction Models: Analysis and Challenges29 Mar 2024
- 2023Leveraging Transformers to Improve Breast Cancer Classification and Risk Assessment with Multi-modal and Longitudinal Data6 Nov 2023
- 2023Case-level Breast Cancer Prediction for Real Hospital Settings19 Oct 2023
- 2023Generalizing Medical Image Representations via Quaternion Wavelet Networks16 Oct 2023
- 2023Attention-Map Augmentation for Hypercomplex Breast Cancer Classification11 Oct 2023
- 2023The effect of data augmentation and 3D-CNN depth on Alzheimer's Disease detection13 Sep 2023
- 2023Detection of Mild Cognitive Impairment Using Facial Features in Video Conversations29 Aug 2023
- 2023Improving Mass Detection in Mammography Images: A Study of Weakly Supervised Learning and Class Activation Map Methods7 Aug 2023
- 2023MammoDG: Generalisable Deep Learning Breaks the Limits of Cross-Domain Multi-Center Breast Cancer Screening2 Aug 2023
- 2023MDF-Net for abnormality detection by fusing X-rays with clinical data26 Feb 2023
- 2023Open-World Object Detection via Discriminative Class Prototype Learning23 Feb 2023
- 2023Semi-Supervised Approach for Early Stuck Sign Detection in Drilling Operations22 Feb 2023
- 2023On the Within-Group Fairness of Screening Classifiers31 Jan 2023
- 2023On the Feasibility of Machine Learning Augmented Magnetic Resonance for Point-of-Care Identification of Disease27 Jan 2023
- 2022Introduction to Machine Learning for Physicians: A Survival Guide for Data Deluge23 Dec 2022
- 2022Selection by Prediction with Conformal p-values4 Oct 2022
- 2022Multi-view Local Co-occurrence and Global Consistency Learning Improve Mammogram Classification Generalisation21 Sep 2022
- 2022Learning to diagnose common thorax diseases on chest radiographs from radiology reports in Vietnamese11 Sep 2022
- 2022Slice-level Detection of Intracranial Hemorrhage on CT Using Deep Descriptors of Adjacent Slices5 Aug 2022
- 2022Leveraging Smartphone Sensors for Detecting Abnormal Gait for Smart Wearable Mobile Technologies3 Aug 2022
- 2022Estimating and Controlling for Equalized Odds via Sensitive Attribute Predictors25 Jul 2022
- 2022Deep Learning Hyperparameter Optimization for Breast Mass Detection in Mammograms22 Jul 2022
50 newest of 88 All 88 (JSON)
- 2021Do Feature Attribution Methods Correctly Attribute Features?cited by 98
- 2022Selection by Prediction with Conformal p-valuescited by 69
- 2021Memory-aware curriculum federated learning for breast cancer classificationcited by 20
- 2021Machine Learning Towards Intelligent Systems: Applications, Challenges, and Opportunitiescited by 14
- 2021Breast Cancer Diagnosis in Two-View Mammography Using End-to-End Trained EfficientNet-Based Convolutional Networkcited by 13
- 2021Detection and severity classification of COVID-19 in CT images using deep learningcited by 12
- 2022Multi-view Local Co-occurrence and Global Consistency Learning Improve Mammogram Classification Generalisationcited by 12
- 2022Domain generalization in deep learning-based mass detection in mammography: A large-scale multi-center studycited by 10
- 2022Meta Ordinal Regression Forest for Medical Image Classification with Ordinal Labelscited by 7
- 2022Multi-View Hypercomplex Learning for Breast Cancer Screeningcited by 7
- 2023MammoDG: Generalisable Deep Learning Breaks the Limits of Cross-Domain Multi-Center Breast Cancer Screeningcited by 7
- 2021MEDUSA: Multi-scale Encoder-Decoder Self-Attention Deep Neural Network Architecture for Medical Image Analysiscited by 6
12 most cited of 85 All 85 (JSON)
- 2026Lesion-Aware Attention for Mammography Segmentation with Heterogeneous Supervision11 Oct 2026
- 2026M3D-Net: Hierarchical Coordination of Spatial Context, Feature Reuse, and Differential Attention for Mammography Classification23 Sep 2026
- 2026Gradient-Based Latent Decomposition Reveals Mechanisms of Feature Degradation in Weakly Supervised Mammography24 Jul 2026
- 2026A Diagnostic Gap Framework for Evaluating Reconstruction Fidelity in Weakly Supervised Mammography22 Jul 2026
- 2026Unsupervised Domain Adaptation for Calcification Classification in Mammography Across Multi-Site Datasets7 Jul 2026
- 2026Deep Neural Networks with Ordinal Loss for Medical Applications24 Jun 2026
- 2026Evaluating Federated Learning approaches for mammography under breast density heterogeneity9 May 2026
- 2026LUMINA: A Multi-Vendor Mammography Benchmark with Energy Harmonization Protocol15 Mar 2026
- 2025OncoVision: Integrating Mammography and Clinical Data through Attention-Driven Multimodal AI for Enhanced Breast Cancer Diagnosis24 Nov 2025
- 2025Dynamic Residual Encoding with Slide-Level Contrastive Learning for End-to-End Whole Slide Image Representation7 Nov 2025
- 2025Region-of-Interest Augmentation for Mammography Classification under Patient-Level Cross-Validation24 Sep 2025
- 2025Efficient Breast and Ovarian Cancer Classification via ViT-Based Preprocessing and Transfer Learning23 Sep 2025
12 newest of 85 All 85 (JSON)