mlsanityData to 14 Oct 2026

You Cannot Recover What Was Never Measured: Quantifying the Information Ceiling of Ultra-Low-Field MRI Super-Resolution

arXiv 2609.36837 ↗First posted 29 Sep 2026cs.CV cs.LG physics.med-phcited by 0

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Abstract (arXiv)

Generative super-resolution models can turn portable 64 mT MRI into images that look like 3T scans, and the field evaluates them with PSNR, SSIM, and pixelwise uncertainty, most often on pairs built by synthetically degrading high-field images. Prior work acknowledges that these models hallucinate and that the problem is ill posed, but to our knowledge no study measures how much information about the individual subject the real low-field scan actually contains. We measure it. Using paired 64 mT and 3T scans of the same subjects from three public datasets, and a measurement protocol validated on tests whose correct answer is known in advance, we find that, judged over the whole brain, real 64 mT scans carry structure specific to the individual only down to approximately 3 to 4 mm half-pitch in plane, and coarser still through plane. Standard synthetic degradations preserve subject information roughly 1 mm beyond this ceiling, so models trained and benchmarked on synthetic pairs are evaluated on information that real scanners never record. We then test trained diffusion models and a publicly released external model on real paired acquisitions; 24 trained runs of five architectures (GAN, diffusion, and transformer families) give the coverage of the audit. On every subject where faithfulness can be measured, fine output detail is no more correlated with the subject's own 3T scan than with a stranger's, while sample-variance uncertainty does not distinguish fabricated structure from reconstruction difficulty. Because PSNR and SSIM score resemblance to a reference rather than whether detail belongs to the subject, a benchmark scored by them cannot tell recovery from fabrication. Code for the measurement protocol will be released so that recoverability claims can be tested for newer models.

Key facts. No citing papers in the map yet (data through 14 Oct 2026). Builds on 20 of its 37 references that are in the map. First posted on arXiv 29 Sep 2026.

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20 of 37 references.

References · 20

  1. 2020Denoising Diffusion Probabilistic Modelscited by 21,076
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8 more
  1. 2020Joint super-resolution and synthesis of 1 mm isotropic MP-RAGE volumes from clinical MRI exams with scans of different orientation, resolution and contrastcited by 45
  2. 2018Evaluating the Impact of Intensity Normalization on MR Image Synthesiscited by 26
  3. 2023Low-field magnetic resonance image enhancement via stochastic image quality transfercited by 19
  4. 2025MRI super-resolution reconstruction using efficient diffusion probabilistic model with residual shiftingcited by 10
  5. 2023DISGAN: Wavelet-informed Discriminator Guides GAN to MRI Super-resolution with Noise Cleaningcited by 5
  6. 2022Synthetic Low-Field MRI Super-Resolution Via Nested U-Net Architecturecited by 3
  7. 2025Deep learning of personalized priors from past MRI scans enables fast, quality-enhanced point-of-care MRI with low-cost systemscited by 3
  8. 2026ReDiff: Reliability-Guided Diffusion for Trustworthy Ultra-Low-Field to High-Field MRI Synthesiscited by 1

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  3. 2026Domain-Specific Latent Representations Improve the Fidelity of Diffusion-Based Medical Image Super-Resolution
  4. 2026CAHAL: Clinically Applicable resolution enHAncement for Low-resolution MRI scans
  5. 2024Enhance the Image: Super Resolution using Artificial Intelligence in MRI
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  7. 2023InverseSR: 3D Brain MRI Super-Resolution Using a Latent Diffusion Model
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