mlsanityData to 7 Oct 2026

PCQC: Privileged Counterfactual Question Credit for Multi-Turn Medical Dialogue

arXiv 2609.27987 ↗First posted 23 Sep 2026cs.LGcited by 0

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Abstract (arXiv)

Large language models (LLMs) have made substantial progress on medical question-answering, yet effective medical dialogue also requires learning to ask questions that uncover relevant patient information. To train such dialogue policies, a common pipeline combines supervised fine-tuning with reinforcement learning (RL) based on final diagnostic correctness. However, this outcome-based supervision does not directly distinguish the contributions of individual questions and provides no question-level feedback for unexecuted alternatives. To address this gap, we introduce PCQC (Privileged Counterfactual Question Credit), which uses privileged patient information during training to learn from questions never asked. During training, PCQC makes alternative questions directly comparable at the same dialogue state by using privileged patient facts to construct their answers. A frozen diagnostic scorer evaluates the diagnostic utility of each resulting question-answer pair by how strongly it supports the correct diagnosis. PCQC turns these comparisons into relative question credit that teaches the policy which questions to favor, directly supervising both executed and unexecuted questions alongside outcome-based RL without requiring complete rollouts for the unexecuted alternatives. Extensive experiments across four medical benchmarks demonstrate that PCQC achieves 63.10% mean diagnostic accuracy, outperforming GRPO and ATPO by 4.38 and 4.21 percentage points, respectively. These gains are achieved with 33.1% fewer inquiry turns than GRPO.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Builds on 14 of its 21 references that are in the map. First posted on arXiv 23 Sep 2026.

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References · 14

  1. 2017Proximal Policy Optimization Algorithmscited by 14,441
  2. 2022Large Language Models Encode Clinical Knowledgecited by 1,807
  3. 2025Group-in-Group Policy Optimization for LLM Agent Trainingcited by 442
  4. 2019Learning by Cheatingcited by 361
  5. 2017Asymmetric Actor Critic for Image-Based Robot Learningcited by 202
  6. 2024VinePPO: Refining Credit Assignment in RL Training of LLMscited by 168
  7. 2024MediQ: Question-Asking LLMs and a Benchmark for Reliable Interactive Clinical Reasoningcited by 145
  8. 2025Information Gain-based Policy Optimization: A Simple and Effective Approach for Multi-Turn Search Agentscited by 43
  9. 2025ALFA: Aligning LLMs to Ask Good Questions A Case Study in Clinical Reasoningcited by 24
  10. 2026TIPS: Turn-Level Information-Potential Reward Shaping for Search-Augmented LLMscited by 24
  11. 2025ProMed: Shapley Information Gain Guided Reinforcement Learning for Proactive Medical LLMscited by 12
  12. 2025Doctor-R1: Mastering Clinical Inquiry with Experiential Agentic Reinforcement Learningcited by 11
2 more
  1. 2026InfoPO: Information-Driven Policy Optimization for User-Centric Agentscited by 8
  2. 2026ATPO: Adaptive Tree Policy Optimization for Multi-Turn Medical Dialoguecited by 8

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  1. 2026Aligning Medical Conversational AI through Online Reinforcement Learning with Information-Theoretic Rewards
  2. 2024Integrating Physician Diagnostic Logic into Large Language Models: Preference Learning from Process Feedback
  3. 2025Dialogue is Better Than Monologue: Instructing Medical LLMs via Strategical Conversations
  4. 2025Med-U1: Incentivizing Unified Medical Reasoning in LLMs via Large-scale Reinforcement Learning
  5. 2026ConRub-Med: Reinforcement Learning with Consensus Rubrics for Open-Ended Medical Question Answering
  6. 2023Zhongjing: Enhancing the Chinese Medical Capabilities of Large Language Model through Expert Feedback and Real-world Multi-turn Dialogue
  7. 2026PrivMedChat: End-to-End Differentially Private RLHF for Medical Dialogue Systems
  8. 2025GraphMed-LT: Patient-Specific Graph Memory with Latent Clinical Thought Refinement for Multi-Turn Medical Conversations